hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00516
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| TMEM242 | Transmembrane protein 242 | UniProt NCBI |
| SLC22A9 | Solute carrier family 22 member 9 (Organic anion transporter 7) | UniProt NCBI |
| TRIM13 | E3 ubiquitin-protein ligase TRIM13 (EC 2.3.2.27) (B-cell chronic lymphocytic leukemia tumor suppressor Leu5) (Leukemia-associated protein 5) (Putative tumor suppressor RFP2) (RING finger protein 77) (RING-type E3 ubiquitin transferase TRIM13) (Ret finger protein 2) (Tripartite motif-containing protein 13) | UniProt NCBI |
| SLC29A2 | Equilibrative nucleoside transporter 2 (36 kDa nucleolar protein HNP36) (Delayed-early response protein 12) (Equilibrative nitrobenzylmercaptopurine riboside-insensitive nucleoside transporter) (Equilibrative NBMPR-insensitive nucleoside transporter) (Hydrophobic nucleolar protein, 36 kDa) (Nucleoside transporter, ei-type) (Solute carrier family 29 member 2) | UniProt NCBI |
| ELOVL2 | Elongation of very long chain fatty acids protein 2 (EC 2.3.1.199) (3-keto acyl-CoA synthase ELOVL2) (ELOVL fatty acid elongase 2) (ELOVL FA elongase 2) (Very long chain 3-ketoacyl-CoA synthase 2) (Very long chain 3-oxoacyl-CoA synthase 2) | UniProt NCBI |
| ELOVL5 | Elongation of very long chain fatty acids protein 5 (EC 2.3.1.199) (3-keto acyl-CoA synthase ELOVL5) (ELOVL fatty acid elongase 5) (ELOVL FA elongase 5) (Fatty acid elongase 1) (hELO1) (Very long chain 3-ketoacyl-CoA synthase 5) (Very long chain 3-oxoacyl-CoA synthase 5) | UniProt NCBI |
| ORMDL1 | ORM1-like protein 1 (Adoplin-1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-2046105 | 0.000664182971726 | 0.285714285714 | ELOVL2 ELOVL5 | Linoleic acid (LA) metabolism |
| REAC:R-HSA-2046104 | 0.00173796966748 | 0.285714285714 | ELOVL2 ELOVL5 | alpha-linolenic (omega3) and linoleic (omega6) acid metabolism |
| REAC:R-HSA-2046106 | 0.00173796966748 | 0.285714285714 | ELOVL2 ELOVL5 | alpha-linolenic acid (ALA) metabolism |
| KEGG:00062 | 0.00249893990045 | 0.285714285714 | ELOVL2 ELOVL5 | Fatty acid elongation |
| KEGG:01040 | 0.00272550577162 | 0.285714285714 | ELOVL2 ELOVL5 | Biosynthesis of unsaturated fatty acids |
| REAC:R-HSA-75876 | 0.00599180765553 | 0.285714285714 | ELOVL2 ELOVL5 | Synthesis of very long-chain fatty acyl-CoAs |
| KEGG:01212 | 0.0135196539521 | 0.285714285714 | ELOVL2 ELOVL5 | Fatty acid metabolism |
| REAC:R-HSA-75105 | 0.0146280770201 | 0.285714285714 | ELOVL2 ELOVL5 | Fatty acyl-CoA biosynthesis |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| TMEM242 | SLC22A9 | 0.081 | 0.35 | bioplex (SLC22A9) bioplex_WMM |
| ELOVL2 | SLC22A9 | 0.068 | 0.35 | bioplex (SLC22A9) bioplex_WMM |
| SLC22A9 | SLC29A2 | 0.039 | 0.266 | bioplex (SLC22A9) bioplex_WMM |
| ELOVL2 | TRIM13 | 0.034 | 0.262 | bioplex (TRIM13) bioplex_WMM youn_WMM |
| ORMDL1 | SLC22A9 | 0.021 | 0.186 | bioplex (SLC22A9) bioplex_WMM |
| SLC22A9 | ELOVL5 | 0.02 | 0.188 | bioplex (SLC22A9) bioplex_WMM |
| ORMDL1 | SLC29A2 | 0.008 | 0.091 | bioplex_WMM WMM_only |
| TMEM242 | SLC29A2 | 0.008 | 0.087 | bioplex_WMM WMM_only |
| ELOVL5 | SLC29A2 | 0.008 | 0.085 | bioplex_WMM WMM_only |
| ORMDL1 | ELOVL5 | 0.008 | 0.073 | bioplex_WMM gupta_WMM WMM_only |
| TMEM242 | ORMDL1 | 0.008 | 0.067 | bioplex_WMM WMM_only |
| ELOVL2 | SLC29A2 | 0.008 | 0.06 | bioplex_WMM WMM_only |
| TMEM242 | ELOVL5 | 0.008 | 0.04 | bioplex_WMM WMM_only |
| ORMDL1 | ELOVL2 | 0.008 | 0.025 | bioplex_WMM WMM_only |
| TMEM242 | ELOVL2 | 0.008 | 0.015 | bioplex_WMM WMM_only |
| ELOVL2 | ELOVL5 | 0.007 | 0.012 | bioplex_WMM WMM_only |
| ELOVL5 | TRIM13 | 0.007 | 0.0 | gupta_WMM WMM_only |
| ORMDL1 | TRIM13 | 0.007 | 0.001 | gupta_WMM WMM_only |
Images
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Complex HuMAP2_00516 has an average edge precision of 0.12 which is ranked 6870 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| TMEM242 | HuMAP2_00516 HuMAP2_01900 |
| SLC22A9 | HuMAP2_00516 HuMAP2_01900 |
| TRIM13 | HuMAP2_00516 HuMAP2_03135 |
| SLC29A2 | HuMAP2_00516 |
| ELOVL2 | HuMAP2_00516 HuMAP2_01900 HuMAP2_03135 |
| ELOVL5 | HuMAP2_00516 HuMAP2_02958 |
| ORMDL1 | HuMAP2_00516 |