hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00517
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| WDR26 | WD repeat-containing protein 26 (CUL4- and DDB1-associated WDR protein 2) (Myocardial ischemic preconditioning up-regulated protein 2) | UniProt NCBI |
| MAEA | E3 ubiquitin-protein transferase MAEA (EC 2.3.2.27) (Cell proliferation-inducing gene 5 protein) (Erythroblast macrophage protein) (Human lung cancer oncogene 10 protein) (HLC-10) (Macrophage erythroblast attacher) (P44EMLP) | UniProt NCBI |
| GID8 | Glucose-induced degradation protein 8 homolog (Two hybrid-associated protein 1 with RanBPM) (Twa1) | UniProt NCBI |
| RANBP9 | Ran-binding protein 9 (RanBP9) (BPM-L) (BPM90) (Ran-binding protein M) (RanBPM) (RanBP7) | UniProt NCBI |
| RANBP10 | Ran-binding protein 10 (RanBP10) | UniProt NCBI |
| ARMC8 | Armadillo repeat-containing protein 8 | UniProt NCBI |
| YPEL5 | Protein yippee-like 5 | UniProt NCBI |
| MKLN1 | Muskelin | UniProt NCBI |
| RMND5A | E3 ubiquitin-protein transferase RMND5A (EC 2.3.2.27) (P44CTLH) (Protein RMD5 homolog A) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:3071 | 8.53043734036e-16 | 0.555555555556 | RANBP9 MKLN1 ARMC8 RMND5A MAEA | CTLH complex |
| WP:WP4352 | 1.21199306326e-15 | 1.0 | RANBP9 ARMC8 GID8 MAEA RANBP10 RMND5A MKLN1 WDR26 YPEL5 | Ciliary landscape |
| GO:0000151 | 5.89927862092e-12 | 1.0 | RANBP9 ARMC8 GID8 MAEA RANBP10 RMND5A MKLN1 WDR26 YPEL5 | ubiquitin ligase complex |
| CORUM:639 | 2.52114215054e-08 | 0.333333333333 | RANBP9 MKLN1 GID8 | RANBPM-Muskelin-TWA1-HSMpp8 complex |
| GO:1990234 | 5.25719457291e-08 | 1.0 | RANBP9 ARMC8 GID8 MAEA RANBP10 RMND5A MKLN1 WDR26 YPEL5 | transferase complex |
| GO:1902494 | 6.70061170383e-06 | 1.0 | RANBP9 ARMC8 GID8 MAEA RANBP10 RMND5A MKLN1 WDR26 YPEL5 | catalytic complex |
| GO:0034657 | 3.05058200216e-05 | 0.333333333333 | MAEA ARMC8 RMND5A | GID complex |
| REAC:R-HSA-8851805 | 0.00232265605894 | 0.222222222222 | RANBP9 RANBP10 | MET activates RAS signaling |
| WP:000000 | 0.00566194757866 | 1.0 | RANBP9 ARMC8 GID8 MAEA RANBP10 RMND5A MKLN1 WDR26 YPEL5 | WIKIPATHWAYS |
| TF:M03896_1 | 0.0151052972756 | 0.888888888889 | RANBP9 YPEL5 GID8 MAEA RANBP10 RMND5A MKLN1 WDR26 | Factor: EGR1; motif: NACGCCCACGCANW; match class: 1 |
| CORUM:641 | 0.0249698419797 | 0.111111111111 | RANBP9 | RANBPM-SMP1 complex |
| HPA:013010_22 | 0.0298007920886 | 0.555555555556 | RANBP9 MAEA YPEL5 ARMC8 GID8 | endometrium 1; cells in endometrial stroma[Approved,Medium] |
| CORUM:0000000 | 0.0319384059855 | 0.777777777778 | RANBP9 ARMC8 GID8 MAEA RMND5A MKLN1 WDR26 | CORUM root |
| CORUM:5757 | 0.0499262710315 | 0.111111111111 | RANBP9 | PLXNA1-RANBPM complex |
| CORUM:5758 | 0.0499262710315 | 0.111111111111 | RANBP9 | PLXNA2-RANBPM complex |
| CORUM:5759 | 0.0499262710315 | 0.111111111111 | RANBP9 | PLXNA3-RANBPM complex |
| CORUM:5760 | 0.0499262710315 | 0.111111111111 | RANBP9 | PLXNA4-RANBPM complex |
| CORUM:6961 | 0.0499262710315 | 0.111111111111 | GID8 | CTNNB1-GID8 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RANBP9 | GID8 | 1.0 | 0.949 | hein_WMM bioplex_WMM boldt (GID8,RANBP9) youn_WMM Malo fraction boldt_WMM |
| RMND5A | WDR26 | 1.0 | 0.949 | bioplex (RMND5A) bioplex_WMM boldt (RMND5A,WDR26) youn_WMM boldt_WMM |
| RMND5A | RANBP10 | 1.0 | 0.949 | hein_WMM bioplex (RMND5A) bioplex_WMM boldt (RANBP10,RMND5A) boldt_WMM |
| RMND5A | YPEL5 | 1.0 | 0.949 | hein_WMM bioplex (RMND5A) bioplex_WMM boldt hein (YPEL5) boldt_WMM |
| RMND5A | ARMC8 | 1.0 | 0.949 | hein_WMM bioplex (RMND5A) bioplex_WMM boldt (ARMC8,RMND5A) boldt_WMM |
| RANBP9 | MAEA | 1.0 | 0.949 | hein_WMM bioplex_WMM boldt (MAEA,RANBP9) youn_WMM Malo fraction boldt_WMM |
| RMND5A | RANBP9 | 1.0 | 0.949 | hein_WMM bioplex (RMND5A) bioplex_WMM boldt (RANBP9,RMND5A) youn_WMM boldt_WMM |
| GID8 | RANBP10 | 1.0 | 0.949 | hein_WMM bioplex_WMM boldt Malo fraction boldt_WMM |
| RMND5A | MKLN1 | 1.0 | 0.949 | hein_WMM bioplex (RMND5A) bioplex_WMM boldt (MKLN1,RMND5A) youn_WMM boldt_WMM |
| RMND5A | MAEA | 1.0 | 0.949 | hein_WMM bioplex (RMND5A) bioplex_WMM boldt youn_WMM boldt_WMM |
| WDR26 | RANBP10 | 1.0 | 0.949 | bioplex_WMM boldt (RANBP10,WDR26) Malo fraction boldt_WMM |
| RANBP10 | YPEL5 | 1.0 | 0.949 | hein_WMM bioplex_WMM boldt (RANBP10,YPEL5) hein (YPEL5) boldt_WMM |
| RANBP9 | MKLN1 | 1.0 | 0.949 | hein_WMM bioplex_WMM boldt (MKLN1,RANBP9) youn_WMM hein (MKLN1) boldt_WMM |
| RANBP9 | YPEL5 | 1.0 | 0.949 | hein_WMM bioplex_WMM boldt (RANBP9,YPEL5) hein (YPEL5) boldt_WMM |
| ARMC8 | YPEL5 | 1.0 | 0.949 | hein_WMM bioplex_WMM boldt (ARMC8,YPEL5) hein (YPEL5) boldt_WMM |
| RMND5A | GID8 | 1.0 | 0.949 | hein_WMM bioplex (RMND5A) bioplex_WMM boldt (GID8,RMND5A) youn_WMM boldt_WMM |
| MAEA | YPEL5 | 1.0 | 0.949 | hein_WMM bioplex_WMM boldt hein (YPEL5) boldt_WMM |
| GID8 | YPEL5 | 0.999 | 0.949 | hein_WMM bioplex_WMM boldt hein (YPEL5) boldt_WMM |
| GID8 | MKLN1 | 0.995 | 0.923 | hein_WMM bioplex_WMM boldt youn_WMM hein (MKLN1) boldt_WMM |
| RANBP9 | RANBP10 | 0.958 | 0.863 | hein_WMM bioplex_WMM boldt (RANBP10,RANBP9) boldt_WMM |
| RANBP10 | ARMC8 | 0.942 | 0.855 | hein_WMM bioplex_WMM boldt (ARMC8,RANBP10) boldt_WMM |
| MAEA | ARMC8 | 0.939 | 0.85 | hein_WMM bioplex_WMM boldt (ARMC8,MAEA) youn_WMM boldt_WMM |
| MAEA | RANBP10 | 0.937 | 0.85 | hein_WMM bioplex_WMM boldt (MAEA,RANBP10) boldt_WMM |
| RANBP9 | ARMC8 | 0.929 | 0.845 | hein_WMM bioplex_WMM boldt (ARMC8,RANBP9) youn_WMM boldt_WMM |
| MKLN1 | YPEL5 | 0.908 | 0.831 | hein_WMM bioplex_WMM boldt hein (YPEL5) boldt_WMM |
| RANBP9 | WDR26 | 0.845 | 0.789 | bioplex_WMM boldt (RANBP9,WDR26) youn_WMM boldt_WMM |
| MAEA | MKLN1 | 0.787 | 0.757 | hein_WMM bioplex_WMM boldt (MAEA,MKLN1) youn_WMM boldt_WMM |
| WDR26 | MAEA | 0.737 | 0.738 | bioplex_WMM boldt (MAEA,WDR26) youn_WMM boldt_WMM |
| ARMC8 | MKLN1 | 0.736 | 0.738 | hein_WMM bioplex_WMM boldt (ARMC8,MKLN1) boldt_WMM |
| GID8 | MAEA | 0.728 | 0.735 | hein_WMM bioplex_WMM boldt (GID8,MAEA) youn_WMM boldt_WMM |
| WDR26 | ARMC8 | 0.531 | 0.636 | bioplex_WMM boldt (ARMC8,WDR26) youn_WMM boldt_WMM |
| WDR26 | YPEL5 | 0.397 | 0.557 | bioplex_WMM boldt (WDR26,YPEL5) boldt_WMM |
| GID8 | ARMC8 | 0.374 | 0.546 | hein_WMM bioplex_WMM boldt (ARMC8) youn_WMM boldt_WMM |
| WDR26 | GID8 | 0.336 | 0.527 | bioplex_WMM boldt (GID8,WDR26) youn_WMM boldt_WMM |
| RANBP10 | MKLN1 | 0.116 | 0.387 | hein_WMM bioplex_WMM boldt boldt_WMM |
| WDR26 | MKLN1 | 0.095 | 0.359 | bioplex_WMM boldt (MKLN1) youn_WMM boldt_WMM |
Images
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Complex HuMAP2_00517 has an average edge precision of 0.83 which is ranked 835 out of all 6965 complexes.
Related Complexes