hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00525
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ADA2 | Adenosine deaminase 2 (EC 3.5.4.4) (Cat eye syndrome critical region protein 1) | UniProt NCBI |
| GSS | Glutathione synthetase (GSH synthetase) (GSH-S) (EC 6.3.2.3) (Glutathione synthase) | UniProt NCBI |
| PCNP | PEST proteolytic signal-containing nuclear protein (PCNP) (PEST-containing nuclear protein) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| MIRNA:hsa-miR-3656 | 0.0166420052318 | 0.666666666667 | PCNP ADA2 | hsa-miR-3656 |
| MIRNA:hsa-miR-610 | 0.0215875890757 | 0.666666666667 | GSS PCNP | hsa-miR-610 |
| WP:WP4518 | 0.0428416541517 | 0.333333333333 | GSS | Gamma-Glutamyl Cycle for the biosynthesis and degradation of glutathione, including diseases |
| REAC:R-HSA-5579006 | 0.0498572752401 | 0.333333333333 | GSS | Defective GSS causes Glutathione synthetase deficiency (GSS deficiency) |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| GSS | ADA2 | 0.061 | 0.339 | fraction |
| GSS | PCNP | 0.022 | 0.208 | bioplex_WMM fraction |
Images
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Complex HuMAP2_00525 has an average edge precision of 0.274 which is ranked 4974 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ADA2 | HuMAP2_00525 HuMAP2_05142 |
| GSS | HuMAP2_00525 HuMAP2_03318 HuMAP2_05142 |
| PCNP | HuMAP2_00525 HuMAP2_05120 |