hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00532
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DAB2 | Disabled homolog 2 (Adaptor molecule disabled-2) (Differentially expressed in ovarian carcinoma 2) (DOC-2) (Differentially-expressed protein 2) | UniProt NCBI |
| FCHO1 | F-BAR domain only protein 1 | UniProt NCBI |
| SLC25A41 | Solute carrier family 25 member 41 | UniProt NCBI |
| FCHO2 | F-BAR domain only protein 2 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-8856825 | 0.000152699585722 | 0.75 | DAB2 FCHO1 FCHO2 | Cargo recognition for clathrin-mediated endocytosis |
| REAC:R-HSA-8856828 | 0.000468996589794 | 0.75 | DAB2 FCHO1 FCHO2 | Clathrin-mediated endocytosis |
| GO:0072583 | 0.00163061517788 | 0.75 | DAB2 FCHO1 FCHO2 | clathrin-dependent endocytosis |
| GO:0005905 | 0.00197902980402 | 0.75 | DAB2 FCHO1 FCHO2 | clathrin-coated pit |
| REAC:R-HSA-199991 | 0.0426366599823 | 0.75 | DAB2 FCHO1 FCHO2 | Membrane Trafficking |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DAB2 | FCHO2 | 0.925 | 0.843 | hein_WMM bioplex (DAB2) bioplex_WMM |
| FCHO2 | FCHO1 | 0.267 | 0.483 | bioplex (FCHO1) bioplex_WMM |
| DAB2 | SLC25A41 | 0.043 | 0.269 | bioplex (SLC25A41) bioplex_WMM |
| FCHO2 | SLC25A41 | 0.031 | 0.238 | bioplex (SLC25A41) bioplex_WMM |
Images
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Complex HuMAP2_00532 has an average edge precision of 0.458 which is ranked 2814 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| DAB2 | HuMAP2_00137 HuMAP2_00532 HuMAP2_01298 HuMAP2_04526 HuMAP2_06848 |
| FCHO1 | HuMAP2_00137 HuMAP2_00532 HuMAP2_01298 |
| SLC25A41 | HuMAP2_00137 HuMAP2_00532 HuMAP2_01298 HuMAP2_01870 |
| FCHO2 | HuMAP2_00137 HuMAP2_00532 HuMAP2_01298 HuMAP2_03002 HuMAP2_04526 |