hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_00541
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SEC13 | Protein SEC13 homolog (GATOR complex protein SEC13) (SEC13-like protein 1) (SEC13-related protein) | UniProt NCBI |
| AHCTF1 | Protein ELYS (Embryonic large molecule derived from yolk sac) (Protein MEL-28) (Putative AT-hook-containing transcription factor 1) | UniProt NCBI |
| SMPD4 | Sphingomyelin phosphodiesterase 4 (EC 3.1.4.12) (Neutral sphingomyelinase 3) (nSMase-3) (nSMase3) (Neutral sphingomyelinase III) | UniProt NCBI |
| AAAS | Aladin (Adracalin) | UniProt NCBI |
| SEH1L | Nucleoporin SEH1 (GATOR complex protein SEH1) (Nup107-160 subcomplex subunit SEH1) (SEC13-like protein) | UniProt NCBI |
| NUP160 | Nuclear pore complex protein Nup160 (160 kDa nucleoporin) (Nucleoporin Nup160) | UniProt NCBI |
| NUP85 | Nuclear pore complex protein Nup85 (85 kDa nucleoporin) (FROUNT) (Nucleoporin Nup75) (Nucleoporin Nup85) (Pericentrin-1) | UniProt NCBI |
| WDR24 | GATOR complex protein WDR24 (WD repeat-containing protein 24) | UniProt NCBI |
| SESN2 | Sestrin-2 (EC 1.11.1.15) (Hypoxia-induced gene) | UniProt NCBI |
| NUP98 | Nuclear pore complex protein Nup98-Nup96 (EC 3.4.21.-) [Cleaved into: Nuclear pore complex protein Nup98 (98 kDa nucleoporin) (Nucleoporin Nup98) (Nup98); Nuclear pore complex protein Nup96 (96 kDa nucleoporin) (Nucleoporin Nup96) (Nup96)] | UniProt NCBI |
| MIOS | GATOR complex protein MIOS (Missing oocyte meiosis regulator homolog) | UniProt NCBI |
| NUP43 | Nucleoporin Nup43 (Nup107-160 subcomplex subunit Nup43) (p42) | UniProt NCBI |
| NUP107 | Nuclear pore complex protein Nup107 (107 kDa nucleoporin) (Nucleoporin Nup107) | UniProt NCBI |
| NUP133 | Nuclear pore complex protein Nup133 (133 kDa nucleoporin) (Nucleoporin Nup133) | UniProt NCBI |
| NUP37 | Nucleoporin Nup37 (p37) (Nup107-160 subcomplex subunit Nup37) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0031080 | 1.01738963647e-27 | 0.666666666667 | NUP98 SEH1L NUP160 NUP43 AHCTF1 NUP107 NUP85 NUP133 NUP37 SEC13 | nuclear pore outer ring |
| CORUM:87 | 2.49898428034e-27 | 0.6 | NUP98 SEH1L NUP160 NUP43 NUP107 NUP85 NUP133 NUP37 SEC13 | Nup 107-160 subcomplex |
| GO:0071431 | 9.35109769629e-20 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | tRNA-containing ribonucleoprotein complex export from nucleus |
| GO:0006409 | 9.35109769629e-20 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | tRNA export from nucleus |
| GO:0051031 | 1.85350019511e-19 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | tRNA transport |
| GO:0097064 | 3.51474683152e-19 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | ncRNA export from nucleus |
| GO:0005643 | 2.24671166234e-18 | 0.733333333333 | NUP98 NUP107 NUP160 NUP43 AHCTF1 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | nuclear pore |
| GO:0075733 | 2.40214331693e-17 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | intracellular transport of virus |
| GO:0046794 | 4.33069174837e-17 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | transport of virus |
| REAC:R-HSA-170822 | 8.89435206275e-17 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Regulation of Glucokinase by Glucokinase Regulatory Protein |
| REAC:R-HSA-168333 | 8.89435206275e-17 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | NEP/NS2 Interacts with the Cellular Export Machinery |
| REAC:R-HSA-168271 | 8.89435206275e-17 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Transport of Ribonucleoproteins into the Host Nucleus |
| REAC:R-HSA-5619107 | 8.89435206275e-17 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC) |
| REAC:R-HSA-168274 | 8.89435206275e-17 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Export of Viral Ribonucleoproteins from Nucleus |
| GO:0006110 | 1.5158240859e-16 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | regulation of glycolytic process |
| REAC:R-HSA-180746 | 1.67350896293e-16 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Nuclear import of Rev protein |
| REAC:R-HSA-159227 | 1.67350896293e-16 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Transport of the SLBP independent Mature mRNA |
| REAC:R-HSA-180910 | 1.67350896293e-16 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Vpr-mediated nuclear import of PICs |
| REAC:R-HSA-4085377 | 2.25465506884e-16 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | SUMOylation of SUMOylation proteins |
| REAC:R-HSA-165054 | 2.25465506884e-16 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Rev-mediated nuclear export of HIV RNA |
| REAC:R-HSA-159230 | 2.25465506884e-16 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Transport of the SLBP Dependant Mature mRNA |
| REAC:R-HSA-3301854 | 3.00494859144e-16 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Nuclear Pore Complex (NPC) Disassembly |
| GO:0043470 | 3.39756577159e-16 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | regulation of carbohydrate catabolic process |
| GO:0044766 | 3.39756577159e-16 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | multi-organism transport |
| GO:1902579 | 3.39756577159e-16 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | multi-organism localization |
| REAC:R-HSA-176033 | 3.96487196354e-16 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Interactions of Vpr with host cellular proteins |
| REAC:R-HSA-177243 | 3.96487196354e-16 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Interactions of Rev with host cellular proteins |
| REAC:R-HSA-3232142 | 5.18266235548e-16 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | SUMOylation of ubiquitinylation proteins |
| GO:1900034 | 9.5170782311e-16 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | regulation of cellular response to heat |
| REAC:R-HSA-168276 | 1.10067694595e-15 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | NS1 Mediated Effects on Host Pathways |
| REAC:R-HSA-159231 | 1.10067694595e-15 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Transport of Mature mRNA Derived from an Intronless Transcript |
| REAC:R-HSA-168253 | 1.39360710352e-15 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Host Interactions with Influenza Factors |
| REAC:R-HSA-159234 | 1.39360710352e-15 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Transport of Mature mRNAs Derived from Intronless Transcripts |
| KEGG:03013 | 1.49228361147e-15 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | RNA transport |
| REAC:R-HSA-168325 | 2.18972474462e-15 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Viral Messenger RNA Synthesis |
| REAC:R-HSA-4615885 | 3.35788659338e-15 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | SUMOylation of DNA replication proteins |
| REAC:R-HSA-4570464 | 3.35788659338e-15 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | SUMOylation of RNA binding proteins |
| GO:1900542 | 3.51962584198e-15 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | regulation of purine nucleotide metabolic process |
| GO:0006140 | 4.48380369337e-15 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | regulation of nucleotide metabolic process |
| REAC:R-HSA-2980766 | 6.12465511369e-15 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Nuclear Envelope Breakdown |
| GO:1903578 | 7.15417028679e-15 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | regulation of ATP metabolic process |
| GO:0006096 | 8.0136585487e-15 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | glycolytic process |
| GO:0006757 | 8.96491338193e-15 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | ATP generation from ADP |
| GO:0046031 | 1.11778152818e-14 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | ADP metabolic process |
| GO:0009135 | 1.38703094771e-14 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | purine nucleoside diphosphate metabolic process |
| GO:0009179 | 1.38703094771e-14 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | purine ribonucleoside diphosphate metabolic process |
| REAC:R-HSA-191859 | 1.52227635233e-14 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | snRNP Assembly |
| REAC:R-HSA-194441 | 1.52227635233e-14 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Metabolism of non-coding RNA |
| GO:0009185 | 1.71325550412e-14 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | ribonucleoside diphosphate metabolic process |
| GO:0006165 | 1.90094152767e-14 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | nucleoside diphosphate phosphorylation |
| GO:0000776 | 2.1069184972e-14 | 0.666666666667 | NUP98 SEH1L NUP160 NUP43 AHCTF1 NUP107 NUP85 NUP133 NUP37 SEC13 | kinetochore |
| GO:0046939 | 2.1069184972e-14 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | nucleotide phosphorylation |
| GO:0034605 | 2.33275235954e-14 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | cellular response to heat |
| GO:0060964 | 2.85084131264e-14 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | regulation of gene silencing by miRNA |
| REAC:R-HSA-6784531 | 2.94521596607e-14 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | tRNA processing in the nucleus |
| GO:0060966 | 3.47018728773e-14 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | regulation of gene silencing by RNA |
| GO:0006406 | 3.47018728773e-14 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | mRNA export from nucleus |
| GO:0009132 | 3.47018728773e-14 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | nucleoside diphosphate metabolic process |
| GO:0071427 | 3.47018728773e-14 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | mRNA-containing ribonucleoprotein complex export from nucleus |
| GO:0060147 | 3.47018728773e-14 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | regulation of posttranscriptional gene silencing |
| GO:0051028 | 5.58067701308e-14 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | mRNA transport |
| GO:0009408 | 8.78203208389e-14 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | response to heat |
| GO:0043467 | 1.046903712e-13 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | regulation of generation of precursor metabolites and energy |
| GO:0005635 | 1.3454579617e-13 | 0.8 | SMPD4 NUP98 AAAS NUP160 NUP43 AHCTF1 NUP107 NUP85 NUP133 NUP37 SEC13 SEH1L | nuclear envelope |
| GO:0071426 | 1.35487412287e-13 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | ribonucleoprotein complex export from nucleus |
| GO:0016925 | 1.39953257668e-13 | 0.6 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEH1L | protein sumoylation |
| REAC:R-HSA-4551638 | 1.42217347221e-13 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | SUMOylation of chromatin organization proteins |
| REAC:R-HSA-3371453 | 1.42217347221e-13 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Regulation of HSF1-mediated heat shock response |
| GO:0071166 | 1.47432110627e-13 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | ribonucleoprotein complex localization |
| REAC:R-HSA-70171 | 1.61765674453e-13 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Glycolysis |
| GO:0006090 | 1.74202345928e-13 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | pyruvate metabolic process |
| REAC:R-HSA-1169408 | 1.83622971484e-13 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | ISG15 antiviral mechanism |
| REAC:R-HSA-159236 | 2.08018763524e-13 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Transport of Mature mRNA derived from an Intron-Containing Transcript |
| GO:0006405 | 2.82749402709e-13 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | RNA export from nucleus |
| REAC:R-HSA-3108214 | 2.99019400899e-13 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | SUMOylation of DNA damage response and repair proteins |
| GO:0006109 | 3.85597961061e-13 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | regulation of carbohydrate metabolic process |
| REAC:R-HSA-1169410 | 4.23060557391e-13 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Antiviral mechanism by IFN-stimulated genes |
| GO:0000775 | 4.4869647484e-13 | 0.666666666667 | NUP98 SEH1L NUP160 NUP43 AHCTF1 NUP107 NUP85 NUP133 NUP37 SEC13 | chromosome, centromeric region |
| GO:0035195 | 5.20930219342e-13 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | gene silencing by miRNA |
| GO:0009266 | 5.60829134804e-13 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | response to temperature stimulus |
| GO:0031503 | 5.77234357603e-13 | 0.733333333333 | NUP98 NUP107 MIOS NUP43 NUP85 AAAS NUP160 NUP133 NUP37 SEC13 SEH1L | protein-containing complex localization |
| REAC:R-HSA-72202 | 5.89913834479e-13 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Transport of Mature Transcript to Cytoplasm |
| GO:0060968 | 6.9755128227e-13 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | regulation of gene silencing |
| REAC:R-HSA-5619102 | 8.11642080522e-13 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | SLC transporter disorders |
| GO:0035194 | 9.93099660582e-13 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | posttranscriptional gene silencing by RNA |
| REAC:R-HSA-70326 | 9.97112701902e-13 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Glucose metabolism |
| GO:0016441 | 1.064217906e-12 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | posttranscriptional gene silencing |
| GO:0050657 | 1.13988237225e-12 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | nucleic acid transport |
| GO:0050658 | 1.13988237225e-12 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | RNA transport |
| REAC:R-HSA-3371556 | 1.344646107e-12 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Cellular response to heat stress |
| GO:0051236 | 1.39677746033e-12 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | establishment of RNA localization |
| GO:0016052 | 1.49331582506e-12 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | carbohydrate catabolic process |
| GO:0006611 | 1.94235942559e-12 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | protein export from nucleus |
| GO:0031047 | 2.0720805491e-12 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | gene silencing by RNA |
| REAC:R-HSA-141424 | 2.5931375597e-12 | 0.533333333333 | NUP37 NUP85 NUP43 SEC13 NUP107 NUP160 NUP133 AHCTF1 | Amplification of signal from the kinetochores |
| REAC:R-HSA-141444 | 2.5931375597e-12 | 0.533333333333 | NUP37 NUP85 NUP43 SEC13 NUP107 NUP160 NUP133 AHCTF1 | Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal |
| GO:0051168 | 4.10890162114e-12 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | nuclear export |
| GO:0019083 | 4.36276743219e-12 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | viral transcription |
| GO:0015931 | 4.91321919232e-12 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | nucleobase-containing compound transport |
| REAC:R-HSA-5578749 | 6.08372112696e-12 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Transcriptional regulation by small RNAs |
| REAC:R-HSA-72306 | 6.08372112696e-12 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | tRNA processing |
| REAC:R-HSA-69618 | 9.02356762779e-12 | 0.533333333333 | NUP37 NUP85 NUP43 SEC13 NUP107 NUP160 NUP133 AHCTF1 | Mitotic Spindle Checkpoint |
| GO:0006403 | 1.02915015601e-11 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | RNA localization |
| GO:0019080 | 1.14766949398e-11 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | viral gene expression |
| REAC:R-HSA-2500257 | 2.3134933962e-11 | 0.533333333333 | NUP37 NUP85 NUP43 SEC13 NUP107 NUP160 NUP133 AHCTF1 | Resolution of Sister Chromatid Cohesion |
| REAC:R-HSA-162909 | 2.64889511551e-11 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Host Interactions of HIV factors |
| CORUM:1347 | 3.29702388569e-11 | 0.266666666667 | NUP107 NUP133 NUP98 NUP160 | NPC subcomplex (NUP98, NUP107, NUP133, NUP160) |
| REAC:R-HSA-168273 | 4.4530720949e-11 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Influenza Viral RNA Transcription and Replication |
| REAC:R-HSA-211000 | 5.04443518143e-11 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Gene Silencing by RNA |
| REAC:R-HSA-68875 | 5.04443518143e-11 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Mitotic Prophase |
| REAC:R-HSA-5663220 | 5.36502009906e-11 | 0.533333333333 | NUP37 NUP85 NUP43 SEC13 NUP107 NUP160 NUP133 AHCTF1 | RHO GTPases Activate Formins |
| REAC:R-HSA-162599 | 5.36502009906e-11 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Late Phase of HIV Life Cycle |
| REAC:R-HSA-168255 | 7.24964813797e-11 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Influenza Life Cycle |
| GO:0016458 | 8.51713008412e-11 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | gene silencing |
| REAC:R-HSA-162587 | 1.14722677934e-10 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | HIV Life Cycle |
| GO:0019058 | 1.15536731765e-10 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | viral life cycle |
| GO:0046034 | 1.20589119392e-10 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | ATP metabolic process |
| REAC:R-HSA-168254 | 1.28150278549e-10 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Influenza Infection |
| CORUM:6216 | 1.64753767118e-10 | 0.266666666667 | MIOS SEC13 WDR24 SEH1L | GATOR2 complex |
| REAC:R-HSA-5619115 | 1.96569449301e-10 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Disorders of transmembrane transporters |
| REAC:R-HSA-3108232 | 3.25386769037e-10 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | SUMO E3 ligases SUMOylate target proteins |
| GO:0006913 | 4.17624933267e-10 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | nucleocytoplasmic transport |
| REAC:R-HSA-2990846 | 4.3380766896e-10 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | SUMOylation |
| GO:0051169 | 4.67255053985e-10 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | nuclear transport |
| REAC:R-HSA-913531 | 4.7635867599e-10 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Interferon Signaling |
| GO:0098687 | 5.03221352032e-10 | 0.666666666667 | NUP98 SEH1L NUP160 NUP43 AHCTF1 NUP107 NUP85 NUP133 NUP37 SEC13 | chromosomal region |
| REAC:R-HSA-2467813 | 7.16202314397e-10 | 0.533333333333 | NUP37 NUP85 NUP43 SEC13 NUP107 NUP160 NUP133 AHCTF1 | Separation of Sister Chromatids |
| REAC:R-HSA-68882 | 1.01178192512e-09 | 0.533333333333 | NUP37 NUP85 NUP43 SEC13 NUP107 NUP160 NUP133 AHCTF1 | Mitotic Anaphase |
| REAC:R-HSA-68877 | 1.01178192512e-09 | 0.533333333333 | NUP37 NUP85 NUP43 SEC13 NUP107 NUP160 NUP133 AHCTF1 | Mitotic Prometaphase |
| GO:0040029 | 1.02591466552e-09 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | regulation of gene expression, epigenetic |
| GO:0009150 | 1.02591466552e-09 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | purine ribonucleotide metabolic process |
| REAC:R-HSA-2555396 | 1.05532663979e-09 | 0.533333333333 | NUP37 NUP85 NUP43 SEC13 NUP107 NUP160 NUP133 AHCTF1 | Mitotic Metaphase and Anaphase |
| GO:0062012 | 1.34533998433e-09 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | regulation of small molecule metabolic process |
| GO:0009259 | 1.39098092266e-09 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | ribonucleotide metabolic process |
| GO:0019693 | 1.80923111989e-09 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | ribose phosphate metabolic process |
| CORUM:6753 | 2.30246537757e-09 | 0.266666666667 | MIOS SEC13 WDR24 SEH1L | SOG complex |
| CORUM:6217 | 2.30246537757e-09 | 0.266666666667 | MIOS SEC13 WDR24 SEH1L | GATOR complex |
| GO:0010608 | 2.71243619679e-09 | 0.733333333333 | NUP98 NUP107 NUP160 NUP43 SESN2 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | posttranscriptional regulation of gene expression |
| GO:0006163 | 2.73360311977e-09 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | purine nucleotide metabolic process |
| REAC:R-HSA-162906 | 3.52166898127e-09 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | HIV Infection |
| REAC:R-HSA-68886 | 4.56546850737e-09 | 0.6 | NUP107 NUP85 NUP43 AHCTF1 AAAS NUP160 NUP133 NUP37 SEC13 | M Phase |
| GO:0072521 | 5.29491818025e-09 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | purine-containing compound metabolic process |
| REAC:R-HSA-72203 | 5.36406165636e-09 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Processing of Capped Intron-Containing Pre-mRNA |
| GO:0009894 | 7.95555565434e-09 | 0.8 | NUP98 SESN2 NUP107 NUP160 NUP43 WDR24 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | regulation of catabolic process |
| GO:0006091 | 1.22048076e-08 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | generation of precursor metabolites and energy |
| REAC:R-HSA-71387 | 1.28184569516e-08 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Metabolism of carbohydrates |
| GO:0031975 | 1.44229826271e-08 | 0.8 | SMPD4 NUP98 AAAS NUP160 NUP43 AHCTF1 NUP107 NUP85 NUP133 NUP37 SEC13 SEH1L | envelope |
| GO:0031967 | 1.44229826271e-08 | 0.8 | SMPD4 NUP98 AAAS NUP160 NUP43 AHCTF1 NUP107 NUP85 NUP133 NUP37 SEC13 SEH1L | organelle envelope |
| GO:0005975 | 1.46850020781e-08 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | carbohydrate metabolic process |
| GO:0009117 | 1.76085207094e-08 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | nucleotide metabolic process |
| GO:0061700 | 1.94072693502e-08 | 0.333333333333 | MIOS SESN2 SEC13 WDR24 SEH1L | GATOR2 complex |
| GO:0006753 | 2.000592525e-08 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | nucleoside phosphate metabolic process |
| REAC:R-HSA-69620 | 2.6545572172e-08 | 0.533333333333 | NUP37 NUP85 NUP43 SEC13 NUP107 NUP160 NUP133 AHCTF1 | Cell Cycle Checkpoints |
| GO:0006999 | 3.15191564889e-08 | 0.333333333333 | NUP133 NUP107 AHCTF1 NUP98 SEH1L | nuclear pore organization |
| REAC:R-HSA-195258 | 4.78204600469e-08 | 0.533333333333 | NUP37 NUP85 NUP43 SEC13 NUP107 NUP160 NUP133 AHCTF1 | RHO GTPase Effectors |
| GO:0016032 | 5.37360289817e-08 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | viral process |
| GO:0018205 | 7.08598699498e-08 | 0.6 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEH1L | peptidyl-lysine modification |
| REAC:R-HSA-69278 | 7.50088944747e-08 | 0.6 | NUP107 NUP85 NUP43 AHCTF1 AAAS NUP160 NUP133 NUP37 SEC13 | Cell Cycle, Mitotic |
| GO:0055086 | 1.0002902583e-07 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | nucleobase-containing small molecule metabolic process |
| GO:0032787 | 1.37370205047e-07 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | monocarboxylic acid metabolic process |
| GO:0044403 | 1.40255145093e-07 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | symbiotic process |
| GO:0035859 | 1.5120752137e-07 | 0.333333333333 | MIOS SESN2 SEC13 WDR24 SEH1L | Seh1-associated complex |
| REAC:R-HSA-5663205 | 1.53964266301e-07 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Infectious disease |
| GO:0044419 | 2.4187334052e-07 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | interspecies interaction between organisms |
| REAC:R-HSA-1640170 | 3.70347992573e-07 | 0.6 | NUP107 NUP85 NUP43 AHCTF1 AAAS NUP160 NUP133 NUP37 SEC13 | Cell Cycle |
| REAC:R-HSA-2262752 | 4.247866121e-07 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Cellular responses to stress |
| GO:0019637 | 4.33166053573e-07 | 0.733333333333 | SMPD4 NUP98 AAAS NUP160 NUP43 NUP107 NUP85 NUP133 NUP37 SEC13 SEH1L | organophosphate metabolic process |
| GO:0017056 | 6.41687390724e-07 | 0.333333333333 | NUP85 NUP107 NUP133 NUP98 NUP160 | structural constituent of nuclear pore |
| REAC:R-HSA-194315 | 6.55402506028e-07 | 0.533333333333 | NUP37 NUP85 NUP43 SEC13 NUP107 NUP160 NUP133 AHCTF1 | Signaling by Rho GTPases |
| GO:0080135 | 7.22058874709e-07 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | regulation of cellular response to stress |
| GO:0033554 | 7.7313470579e-07 | 0.866666666667 | NUP98 SESN2 NUP107 MIOS NUP43 WDR24 NUP85 AAAS NUP160 NUP133 NUP37 SEC13 SEH1L | cellular response to stress |
| GO:1901135 | 1.1283370223e-06 | 0.733333333333 | SMPD4 NUP98 AAAS NUP160 NUP43 NUP107 NUP85 NUP133 NUP37 SEC13 SEH1L | carbohydrate derivative metabolic process |
| REAC:R-HSA-8953897 | 1.77303973826e-06 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Cellular responses to external stimuli |
| GO:0009628 | 5.04997737342e-06 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | response to abiotic stimulus |
| HP:0012588 | 6.5511931649e-06 | 0.2 | NUP160 NUP133 NUP85 | Steroid-resistant nephrotic syndrome |
| KEGG:04150 | 1.16929675848e-05 | 0.333333333333 | MIOS SESN2 SEC13 WDR24 SEH1L | mTOR signaling pathway |
| HP:0000097 | 1.4264441197e-05 | 0.266666666667 | NUP85 NUP107 NUP133 NUP160 | Focal segmental glomerulosclerosis |
| GO:0042325 | 1.47389885293e-05 | 0.733333333333 | NUP98 NUP107 NUP160 NUP43 SESN2 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | regulation of phosphorylation |
| REAC:R-HSA-8953854 | 1.70191780275e-05 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Metabolism of RNA |
| GO:0034613 | 1.94023019386e-05 | 0.8 | NUP98 NUP107 MIOS NUP43 SESN2 NUP85 AAAS NUP160 NUP133 NUP37 SEC13 SEH1L | cellular protein localization |
| GO:0070727 | 2.08024529674e-05 | 0.8 | NUP98 NUP107 MIOS NUP43 SESN2 NUP85 AAAS NUP160 NUP133 NUP37 SEC13 SEH1L | cellular macromolecule localization |
| GO:0009056 | 2.35808127712e-05 | 0.866666666667 | SMPD4 NUP98 SESN2 AAAS NUP160 NUP43 WDR24 NUP107 NUP85 NUP133 NUP37 SEC13 SEH1L | catabolic process |
| REAC:R-HSA-1280215 | 2.64012823781e-05 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Cytokine Signaling in Immune system |
| GO:0019752 | 2.76348692858e-05 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | carboxylic acid metabolic process |
| GO:0019220 | 4.4433797586e-05 | 0.733333333333 | NUP98 NUP107 NUP160 NUP43 SESN2 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | regulation of phosphate metabolic process |
| GO:0051174 | 4.4832976661e-05 | 0.733333333333 | NUP98 NUP107 NUP160 NUP43 SESN2 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | regulation of phosphorus metabolic process |
| GO:0043436 | 6.23668821813e-05 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | oxoacid metabolic process |
| GO:0006082 | 7.18623804481e-05 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | organic acid metabolic process |
| GO:0006886 | 8.62211189576e-05 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | intracellular protein transport |
| GO:0032446 | 9.63995411434e-05 | 0.6 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEH1L | protein modification by small protein conjugation |
| HP:0000096 | 0.000128467572075 | 0.266666666667 | NUP85 NUP107 NUP133 NUP160 | Glomerulosclerosis |
| REAC:R-HSA-74160 | 0.000216192408235 | 0.6 | NUP107 NUP85 NUP43 SESN2 AAAS NUP160 NUP133 NUP37 SEC13 | Gene expression (Transcription) |
| GO:0010629 | 0.000259262597613 | 0.733333333333 | NUP98 NUP107 NUP160 NUP43 SESN2 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | negative regulation of gene expression |
| REAC:R-HSA-1643685 | 0.00030519930168 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Disease |
| GO:0008104 | 0.000412350656102 | 0.8 | NUP98 NUP107 MIOS NUP43 SESN2 NUP85 AAAS NUP160 NUP133 NUP37 SEC13 SEH1L | protein localization |
| GO:0080134 | 0.000444899111434 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | regulation of response to stress |
| GO:0032006 | 0.000567038489742 | 0.333333333333 | MIOS SESN2 SEC13 WDR24 SEH1L | regulation of TOR signaling |
| GO:0006950 | 0.000602029705412 | 0.866666666667 | NUP98 SESN2 NUP107 MIOS NUP43 WDR24 NUP85 AAAS NUP160 NUP133 NUP37 SEC13 SEH1L | response to stress |
| GO:0070647 | 0.000757646846027 | 0.6 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEH1L | protein modification by small protein conjugation or removal |
| HP:0012622 | 0.000799205871706 | 0.266666666667 | NUP85 NUP107 NUP133 NUP160 | Chronic kidney disease |
| GO:0006997 | 0.00115216183197 | 0.333333333333 | NUP133 NUP107 AHCTF1 NUP98 SEH1L | nucleus organization |
| GO:0031929 | 0.00121694160594 | 0.333333333333 | MIOS SESN2 SEC13 WDR24 SEH1L | TOR signaling |
| GO:0016310 | 0.00131879096735 | 0.733333333333 | NUP98 NUP107 NUP160 NUP43 SESN2 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | phosphorylation |
| GO:0044427 | 0.00137730139267 | 0.666666666667 | NUP98 SEH1L NUP160 NUP43 AHCTF1 NUP107 NUP85 NUP133 NUP37 SEC13 | chromosomal part |
| GO:0033036 | 0.00140507252341 | 0.8 | NUP98 NUP107 MIOS NUP43 SESN2 NUP85 AAAS NUP160 NUP133 NUP37 SEC13 SEH1L | macromolecule localization |
| GO:0018193 | 0.00145380366321 | 0.6 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEH1L | peptidyl-amino acid modification |
| GO:0032008 | 0.00151715842522 | 0.266666666667 | MIOS SEC13 WDR24 SEH1L | positive regulation of TOR signaling |
| GO:0048583 | 0.00154145415455 | 0.866666666667 | NUP98 SESN2 NUP107 MIOS NUP43 WDR24 NUP85 AAAS NUP160 NUP133 NUP37 SEC13 SEH1L | regulation of response to stimulus |
| GO:1901575 | 0.00163676680876 | 0.733333333333 | SMPD4 NUP98 AAAS NUP160 NUP43 NUP107 NUP85 NUP133 NUP37 SEC13 SEH1L | organic substance catabolic process |
| GO:0034198 | 0.00192475664625 | 0.266666666667 | MIOS WDR24 SESN2 SEH1L | cellular response to amino acid starvation |
| GO:0005694 | 0.00195024839818 | 0.666666666667 | NUP98 SEH1L NUP160 NUP43 AHCTF1 NUP107 NUP85 NUP133 NUP37 SEC13 | chromosome |
| GO:1990928 | 0.00215678379103 | 0.266666666667 | MIOS WDR24 SESN2 SEH1L | response to amino acid starvation |
| GO:0051292 | 0.0023070725905 | 0.2 | NUP107 NUP98 AHCTF1 | nuclear pore complex assembly |
| HP:0003676 | 0.00240863131767 | 0.333333333333 | NUP85 AAAS NUP160 NUP133 NUP107 | Progressive |
| CORUM:0000000 | 0.00244725117857 | 0.733333333333 | NUP98 SEH1L MIOS NUP43 WDR24 NUP85 NUP107 NUP160 NUP133 NUP37 SEC13 | CORUM root |
| KEGG:00000 | 0.00244888183487 | 0.933333333333 | SMPD4 NUP98 SESN2 NUP107 MIOS NUP43 WDR24 NUP85 AAAS NUP160 NUP133 NUP37 SEC13 SEH1L | KEGG root term |
| REAC:R-HSA-597592 | 0.00257009388199 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Post-translational protein modification |
| GO:0051641 | 0.00260713084147 | 0.8 | NUP98 NUP107 MIOS NUP43 SESN2 NUP85 AAAS NUP160 NUP133 NUP37 SEC13 SEH1L | cellular localization |
| HP:0000100 | 0.00266348387445 | 0.266666666667 | NUP85 NUP107 NUP133 NUP160 | Nephrotic syndrome |
| GO:0015031 | 0.00293256270726 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | protein transport |
| GO:0006796 | 0.00295282844037 | 0.8 | SMPD4 NUP98 AAAS NUP160 NUP43 SESN2 NUP107 NUP85 NUP133 NUP37 SEC13 SEH1L | phosphate-containing compound metabolic process |
| GO:0006793 | 0.00332336358597 | 0.8 | SMPD4 NUP98 AAAS NUP160 NUP43 SESN2 NUP107 NUP85 NUP133 NUP37 SEC13 SEH1L | phosphorus metabolic process |
| GO:0015833 | 0.00336241478438 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | peptide transport |
| GO:0042886 | 0.00379363653218 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | amide transport |
| HP:0000095 | 0.00476830637947 | 0.266666666667 | NUP85 NUP107 NUP133 NUP160 | Abnormality of renal glomerulus morphology |
| HP:0031263 | 0.00476830637947 | 0.266666666667 | NUP85 NUP107 NUP133 NUP160 | Abnormal renal corpuscle morphology |
| REAC:R-HSA-1430728 | 0.00518071418983 | 0.6 | SMPD4 AAAS NUP160 NUP43 NUP107 NUP85 NUP133 NUP37 SEC13 | Metabolism |
| GO:0046907 | 0.00601258608036 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | intracellular transport |
| GO:0045184 | 0.00609365691453 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | establishment of protein localization |
| HP:0000093 | 0.00666440496991 | 0.266666666667 | NUP85 NUP107 NUP133 NUP160 | Proteinuria |
| GO:0010605 | 0.00685531191764 | 0.733333333333 | NUP98 NUP107 NUP160 NUP43 SESN2 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | negative regulation of macromolecule metabolic process |
| GO:0044281 | 0.0081944887846 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | small molecule metabolic process |
| HP:0020129 | 0.00835748584155 | 0.266666666667 | NUP85 NUP107 NUP133 NUP160 | Abnormal urine protein level |
| GO:0051704 | 0.00896802482419 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | multi-organism process |
| HP:0011035 | 0.00906769162546 | 0.266666666667 | NUP85 NUP107 NUP133 NUP160 | Abnormal renal cortex morphology |
| GO:0071705 | 0.0127519374122 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | nitrogen compound transport |
| GO:0032991 | 0.0139875206848 | 0.933333333333 | NUP98 SESN2 NUP107 MIOS AHCTF1 NUP43 WDR24 NUP85 AAAS NUP160 NUP133 NUP37 SEC13 SEH1L | protein-containing complex |
| HP:0012575 | 0.0157195939886 | 0.266666666667 | NUP85 NUP107 NUP133 NUP160 | Abnormal nephron morphology |
| GO:0009892 | 0.0172781375323 | 0.733333333333 | NUP98 NUP107 NUP160 NUP43 SESN2 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | negative regulation of metabolic process |
| GO:0046931 | 0.0229593988963 | 0.2 | NUP107 NUP98 AHCTF1 | pore complex assembly |
| GO:0072006 | 0.0231353847333 | 0.266666666667 | NUP85 NUP107 NUP133 NUP160 | nephron development |
| HP:0003679 | 0.0253833213106 | 0.333333333333 | NUP85 AAAS NUP160 NUP133 NUP107 | Pace of progression |
| HP:0003774 | 0.0275957803853 | 0.2 | NUP107 NUP133 NUP85 | Stage 5 chronic kidney disease |
| GO:0034629 | 0.0278624171613 | 0.2 | MIOS NUP133 SEH1L | cellular protein-containing complex localization |
| REAC:R-HSA-168256 | 0.0295391298266 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Immune System |
| REAC:R-HSA-392499 | 0.036581544761 | 0.533333333333 | NUP107 NUP85 NUP43 AAAS NUP160 NUP133 NUP37 SEC13 | Metabolism of proteins |
| GO:0031965 | 0.0380209062742 | 0.333333333333 | NUP133 AAAS AHCTF1 NUP98 NUP107 | nuclear membrane |
| GO:0034504 | 0.0390491758704 | 0.333333333333 | NUP107 NUP133 NUP98 SESN2 NUP85 | protein localization to nucleus |
| GO:0051649 | 0.0427008393544 | 0.666666666667 | NUP98 NUP107 NUP160 NUP43 AAAS NUP85 NUP133 NUP37 SEC13 SEH1L | establishment of localization in cell |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NUP107 | NUP133 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru boldt youn_WMM hein (NUP107) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| NUP107 | NUP85 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru boldt youn_WMM hein (NUP107) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| NUP43 | NUP107 | 1.0 | 0.949 | hein_WMM bioplex (NUP43) bioplex_WMM youn_WMM hein (NUP107) gupta_WMM |
| NUP160 | NUP85 | 1.0 | 0.949 | hein_WMM bioplex_WMM boldt youn_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| NUP43 | NUP98 | 1.0 | 0.949 | hein_WMM bioplex (NUP43) bioplex_WMM hein (NUP98) gupta_WMM |
| NUP107 | NUP37 | 1.0 | 0.949 | hein_WMM bioplex_WMM Guru hein (NUP107) Malo fraction |
| NUP43 | NUP85 | 1.0 | 0.949 | hein_WMM bioplex (NUP43) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| NUP160 | NUP133 | 1.0 | 0.949 | hein_WMM bioplex_WMM boldt youn_WMM Malo gupta_WMM fraction boldt_WMM treiber_WMM |
| NUP43 | NUP160 | 0.999 | 0.949 | hein_WMM bioplex (NUP43) bioplex_WMM gupta_WMM boldt_WMM |
| NUP43 | SEH1L | 0.999 | 0.949 | hein_WMM bioplex (NUP43) bioplex_WMM hein (SEH1L) |
| NUP43 | NUP133 | 0.998 | 0.935 | hein_WMM bioplex (NUP43) bioplex_WMM youn_WMM gupta_WMM |
| NUP43 | NUP37 | 0.995 | 0.924 | hein_WMM bioplex (NUP43) bioplex_WMM |
| SEC13 | NUP107 | 0.995 | 0.923 | hein_WMM bioplex (SEC13) bioplex_WMM boldt youn_WMM hein (NUP107) gupta_WMM boldt_WMM |
| NUP107 | NUP160 | 0.971 | 0.884 | hein_WMM bioplex_WMM boldt youn_WMM hein (NUP107) gupta_WMM boldt_WMM treiber_WMM |
| AHCTF1 | NUP133 | 0.955 | 0.862 | hein_WMM bioplex_WMM youn_WMM Malo gupta_WMM fraction treiber_WMM |
| SEC13 | WDR24 | 0.925 | 0.843 | hein_WMM bioplex (SEC13) bioplex_WMM boldt boldt_WMM |
| NUP98 | NUP85 | 0.846 | 0.789 | hein_WMM bioplex_WMM Guru youn_WMM hein (NUP98) gupta_WMM fraction treiber_WMM |
| SEC13 | NUP37 | 0.831 | 0.778 | hein_WMM bioplex (SEC13) bioplex_WMM Guru fraction |
| MIOS | SEC13 | 0.816 | 0.773 | hein_WMM bioplex (SEC13) bioplex_WMM boldt boldt_WMM |
| SEC13 | NUP133 | 0.631 | 0.681 | hein_WMM bioplex (SEC13) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| SEC13 | NUP98 | 0.63 | 0.681 | hein_WMM bioplex (SEC13) bioplex_WMM youn_WMM hein (NUP98) gupta_WMM fraction boldt_WMM |
| SEC13 | NUP160 | 0.587 | 0.662 | hein_WMM bioplex (SEC13) bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM |
| SEC13 | SEH1L | 0.517 | 0.631 | hein_WMM bioplex (SEC13) bioplex_WMM youn_WMM hein (SEH1L) boldt_WMM |
| NUP98 | NUP133 | 0.42 | 0.573 | hein_WMM bioplex_WMM Guru youn_WMM hein (NUP98) gupta_WMM fraction boldt_WMM treiber_WMM |
| SEC13 | NUP85 | 0.288 | 0.489 | hein_WMM bioplex (SEC13) bioplex_WMM boldt youn_WMM gupta_WMM fraction boldt_WMM |
| NUP98 | NUP107 | 0.263 | 0.481 | hein_WMM bioplex_WMM Guru youn_WMM hein (NUP107,NUP98) gupta_WMM fraction boldt_WMM treiber_WMM |
| NUP98 | NUP160 | 0.239 | 0.469 | hein_WMM bioplex_WMM youn_WMM hein (NUP98) gupta_WMM boldt_WMM treiber_WMM |
| NUP43 | SEC13 | 0.103 | 0.366 | hein_WMM bioplex (NUP43,SEC13) bioplex_WMM gupta_WMM treiber_WMM |
| SEH1L | NUP85 | 0.1 | 0.361 | hein_WMM bioplex_WMM youn_WMM hein (SEH1L) |
| SEH1L | NUP160 | 0.099 | 0.358 | hein_WMM bioplex_WMM youn_WMM hein (SEH1L) gupta_WMM |
| NUP98 | NUP37 | 0.086 | 0.351 | hein_WMM bioplex_WMM hein (NUP98) fraction |
| NUP107 | SEH1L | 0.083 | 0.35 | hein_WMM bioplex_WMM youn_WMM hein (NUP107,SEH1L) |
| NUP85 | NUP133 | 0.078 | 0.352 | hein_WMM bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM treiber_WMM |
| SEH1L | WDR24 | 0.069 | 0.348 | hein_WMM bioplex_WMM hein (SEH1L) boldt_WMM |
| NUP98 | SEH1L | 0.067 | 0.351 | hein_WMM bioplex_WMM youn_WMM hein (NUP98,SEH1L) fraction |
| WDR24 | SESN2 | 0.06 | 0.337 | hein_WMM bioplex_WMM hein (SESN2) |
| NUP160 | NUP37 | 0.053 | 0.301 | hein_WMM bioplex_WMM WMM_only |
| MIOS | SEH1L | 0.045 | 0.283 | hein_WMM bioplex_WMM hein (SEH1L) boldt_WMM |
| NUP85 | NUP37 | 0.044 | 0.275 | hein_WMM bioplex_WMM WMM_only |
| SEH1L | NUP37 | 0.04 | 0.269 | hein_WMM bioplex_WMM hein (SEH1L) |
| SEH1L | NUP133 | 0.039 | 0.263 | hein_WMM bioplex_WMM youn_WMM hein (SEH1L) gupta_WMM |
| MIOS | SESN2 | 0.036 | 0.264 | hein_WMM bioplex_WMM hein (SESN2) |
| NUP107 | AHCTF1 | 0.031 | 0.236 | hein_WMM bioplex_WMM youn_WMM hein (NUP107) gupta_WMM treiber_WMM |
| AAAS | NUP107 | 0.03 | 0.24 | hein_WMM bioplex_WMM youn_WMM hein (NUP107) gupta_WMM |
| SMPD4 | NUP107 | 0.023 | 0.208 | hein_WMM bioplex_WMM youn_WMM hein (NUP107) gupta_WMM |
| NUP133 | NUP37 | 0.02 | 0.19 | hein_WMM bioplex_WMM WMM_only |
| SEH1L | SESN2 | 0.018 | 0.183 | hein_WMM bioplex_WMM hein (SESN2) |
| AAAS | NUP98 | 0.014 | 0.14 | hein_WMM bioplex_WMM youn_WMM hein (NUP98) gupta_WMM |
| MIOS | WDR24 | 0.014 | 0.141 | hein_WMM bioplex_WMM boldt boldt_WMM |
| SEC13 | SESN2 | 0.013 | 0.149 | hein_WMM bioplex (SEC13) bioplex_WMM hein (SESN2) |
| AAAS | NUP85 | 0.012 | 0.145 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| AAAS | NUP43 | 0.012 | 0.146 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| AAAS | NUP160 | 0.012 | 0.147 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| SMPD4 | NUP98 | 0.011 | 0.142 | hein_WMM bioplex_WMM youn_WMM hein (NUP98) gupta_WMM |
| AAAS | SEH1L | 0.011 | 0.141 | hein_WMM bioplex_WMM youn_WMM hein (SEH1L) |
| AAAS | NUP37 | 0.01 | 0.139 | hein_WMM bioplex_WMM WMM_only |
| NUP98 | AHCTF1 | 0.01 | 0.137 | hein_WMM bioplex_WMM youn_WMM hein (NUP98) gupta_WMM |
| SMPD4 | NUP43 | 0.009 | 0.11 | hein_WMM bioplex_WMM WMM_only |
| SMPD4 | SEH1L | 0.009 | 0.097 | hein_WMM bioplex_WMM WMM_only |
| AAAS | NUP133 | 0.008 | 0.095 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| SMPD4 | NUP37 | 0.008 | 0.087 | hein_WMM bioplex_WMM WMM_only |
| SMPD4 | NUP160 | 0.008 | 0.035 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| NUP43 | WDR24 | 0.008 | 0.024 | hein_WMM bioplex_WMM WMM_only |
| NUP43 | SESN2 | 0.008 | 0.025 | bioplex_WMM WMM_only |
| NUP43 | AHCTF1 | 0.008 | 0.012 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| SESN2 | NUP133 | 0.007 | 0.008 | bioplex_WMM WMM_only |
| SMPD4 | AAAS | 0.007 | 0.009 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| WDR24 | NUP37 | 0.007 | 0.01 | hein_WMM bioplex_WMM WMM_only |
| SESN2 | NUP37 | 0.007 | 0.011 | bioplex_WMM WMM_only |
| WDR24 | NUP133 | 0.007 | 0.008 | hein_WMM bioplex_WMM WMM_only |
| NUP107 | SESN2 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| SEH1L | AHCTF1 | 0.007 | 0.002 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| NUP98 | SESN2 | 0.007 | 0.012 | bioplex_WMM WMM_only |
| NUP160 | WDR24 | 0.007 | 0.006 | hein_WMM bioplex_WMM WMM_only |
| NUP107 | WDR24 | 0.007 | 0.004 | hein_WMM bioplex_WMM WMM_only |
| MIOS | NUP43 | 0.007 | 0.011 | hein_WMM bioplex_WMM WMM_only |
| NUP160 | SESN2 | 0.007 | 0.006 | bioplex_WMM WMM_only |
| NUP85 | WDR24 | 0.007 | 0.005 | hein_WMM bioplex_WMM WMM_only |
| AAAS | MIOS | 0.007 | 0.006 | hein_WMM WMM_only |
| MIOS | NUP37 | 0.007 | 0.005 | hein_WMM bioplex_WMM WMM_only |
| NUP98 | WDR24 | 0.007 | 0.001 | hein_WMM bioplex_WMM WMM_only |
| NUP85 | SESN2 | 0.007 | 0.002 | bioplex_WMM WMM_only |
| SEC13 | AHCTF1 | 0.007 | 0.002 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| MIOS | NUP133 | 0.007 | 0.003 | hein_WMM bioplex_WMM WMM_only |
| AAAS | WDR24 | 0.007 | 0.003 | hein_WMM WMM_only |
| MIOS | NUP160 | 0.007 | 0.001 | hein_WMM bioplex_WMM WMM_only |
| SMPD4 | NUP85 | 0.007 | 0.001 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| MIOS | NUP107 | 0.007 | 0.0 | hein_WMM bioplex_WMM WMM_only |
| SMPD4 | SEC13 | 0.007 | 0.002 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| AAAS | SEC13 | 0.007 | 0.007 | hein_WMM bioplex_WMM youn_WMM WMM_only |
| MIOS | NUP85 | 0.007 | 0.004 | hein_WMM bioplex_WMM WMM_only |
| SMPD4 | NUP133 | 0.007 | 0.005 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| MIOS | NUP98 | 0.007 | 0.004 | hein_WMM bioplex_WMM WMM_only |
| AHCTF1 | NUP37 | 0.007 | 0.003 | hein_WMM bioplex_WMM WMM_only |
| NUP160 | AHCTF1 | 0.006 | 0.008 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only treiber_WMM |
| NUP85 | AHCTF1 | 0.005 | 0.007 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| AAAS | AHCTF1 | 0.004 | 0.01 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| SMPD4 | AHCTF1 | 0.003 | 0.016 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
Images
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Complex HuMAP2_00541 has an average edge precision of 0.305 which is ranked 4507 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SEC13 | HuMAP2_00541 HuMAP2_01606 HuMAP2_03792 HuMAP2_05315 HuMAP2_06753 |
| AHCTF1 | HuMAP2_00541 HuMAP2_05560 |
| SMPD4 | HuMAP2_00541 |
| AAAS | HuMAP2_00541 HuMAP2_02320 |
| SEH1L | HuMAP2_00541 HuMAP2_05315 HuMAP2_06753 |
| NUP160 | HuMAP2_00541 HuMAP2_05315 |
| NUP85 | HuMAP2_00541 HuMAP2_05315 |
| WDR24 | HuMAP2_00541 HuMAP2_01606 HuMAP2_03326 HuMAP2_03792 HuMAP2_06753 HuMAP2_06823 |
| SESN2 | HuMAP2_00541 HuMAP2_01606 HuMAP2_02429 HuMAP2_06823 |
| NUP98 | HuMAP2_00541 HuMAP2_01285 HuMAP2_02388 HuMAP2_05544 |
| MIOS | HuMAP2_00541 HuMAP2_01606 HuMAP2_03326 HuMAP2_03792 HuMAP2_06753 |
| NUP43 | HuMAP2_00541 HuMAP2_03411 HuMAP2_04705 HuMAP2_04997 HuMAP2_05315 |
| NUP107 | HuMAP2_00541 HuMAP2_01007 HuMAP2_03792 HuMAP2_05315 HuMAP2_05974 |
| NUP133 | HuMAP2_00541 HuMAP2_05560 HuMAP2_05974 |
| NUP37 | HuMAP2_00541 HuMAP2_03792 HuMAP2_04294 HuMAP2_05315 |