hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00550
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| UBE2Q1 | Ubiquitin-conjugating enzyme E2 Q1 (EC 2.3.2.23) (E2 ubiquitin-conjugating enzyme Q1) (Protein NICE-5) (Ubiquitin carrier protein Q1) (Ubiquitin-protein ligase Q1) | UniProt NCBI |
| PARP1 | Poly [ADP-ribose] polymerase 1 (PARP-1) (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 1) (ARTD1) (DNA ADP-ribosyltransferase PARP1) (EC 2.4.2.-) (NAD(+) ADP-ribosyltransferase 1) (ADPRT 1) (Poly[ADP-ribose] synthase 1) (Protein poly-ADP-ribosyltransferase PARP1) (EC 2.4.2.-) | UniProt NCBI |
| CCNB1 | G2/mitotic-specific cyclin-B1 | UniProt NCBI |
| PPIL4 | Peptidyl-prolyl cis-trans isomerase-like 4 (PPIase) (EC 5.2.1.8) (Cyclophilin-like protein PPIL4) (Rotamase PPIL4) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1005 | 0.000391779955301 | 0.5 | CCNB1 PARP1 | RC complex during G2/M-phase of cell cycle |
| MIRNA:hsa-miR-1229-5p | 0.0196380022518 | 0.5 | PARP1 UBE2Q1 | hsa-miR-1229-5p |
| CORUM:7185 | 0.0249595281251 | 0.25 | CCNB1 | CCNB1-CCNF complex |
| CORUM:5543 | 0.0499140284799 | 0.25 | CCNB1 | CCNB1-CDC2 complex |
| CORUM:5550 | 0.0499140284799 | 0.25 | CCNB1 | CDK1-CCNB1-CCNF complex |
| CORUM:7352 | 0.0499140284799 | 0.25 | PARP1 | PARP1-LIG3 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CCNB1 | PARP1 | 0.033 | 0.247 | youn_WMM gupta_WMM fraction boldt_WMM |
| PARP1 | PPIL4 | 0.029 | 0.23 | bioplex_WMM youn_WMM gupta_WMM fraction |
| CCNB1 | UBE2Q1 | 0.028 | 0.231 | fraction |
| UBE2Q1 | PARP1 | 0.023 | 0.207 | fraction |
| CCNB1 | PPIL4 | 0.007 | 0.003 | youn_WMM WMM_only |
Images
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Complex HuMAP2_00550 has an average edge precision of 0.184 which is ranked 6394 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| UBE2Q1 | HuMAP2_00550 HuMAP2_01026 HuMAP2_01383 HuMAP2_02938 |
| PARP1 | HuMAP2_00550 HuMAP2_00586 HuMAP2_03086 HuMAP2_03648 HuMAP2_04565 HuMAP2_05034 |
| CCNB1 | HuMAP2_00550 HuMAP2_01003 HuMAP2_01010 HuMAP2_02530 HuMAP2_05166 |
| PPIL4 | HuMAP2_00550 HuMAP2_02016 HuMAP2_06459 |