hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00556
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| IGF2BP1 | Insulin-like growth factor 2 mRNA-binding protein 1 (IGF2 mRNA-binding protein 1) (IMP-1) (IMP1) (Coding region determinant-binding protein) (CRD-BP) (IGF-II mRNA-binding protein 1) (VICKZ family member 1) (Zipcode-binding protein 1) (ZBP-1) | UniProt NCBI |
| IGF2BP2 | Insulin-like growth factor 2 mRNA-binding protein 2 (IGF2 mRNA-binding protein 2) (IMP-2) (Hepatocellular carcinoma autoantigen p62) (IGF-II mRNA-binding protein 2) (VICKZ family member 2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-428359 | 5.02777038712e-06 | 1.0 | IGF2BP2 IGF2BP1 | Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA |
| WP:WP3302 | 0.0221931796051 | 0.5 | IGF2BP1 | eIF5A regulation in response to inhibition of the nuclear export system |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| IGF2BP2 | IGF2BP1 | 0.5 | 0.621 | youn (IGF2BP1,IGF2BP2) bioplex_WMM youn_WMM Malo gupta_WMM fraction treiber_WMM |
Images
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Complex HuMAP2_00556 has an average edge precision of 0.621 which is ranked 1824 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| IGF2BP1 | HuMAP2_00556 HuMAP2_03425 HuMAP2_04560 HuMAP2_04632 HuMAP2_06751 |
| IGF2BP2 | HuMAP2_00556 HuMAP2_00999 HuMAP2_04632 HuMAP2_06202 HuMAP2_06751 |