hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00575
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| TNKS | Poly [ADP-ribose] polymerase tankyrase-1 (EC 2.4.2.30) (ADP-ribosyltransferase diphtheria toxin-like 5) (ARTD5) (Poly [ADP-ribose] polymerase 5A) (Protein poly-ADP-ribosyltransferase tankyrase-1) (EC 2.4.2.-) (TNKS-1) (TRF1-interacting ankyrin-related ADP-ribose polymerase) (Tankyrase I) (Tankyrase-1) (TANK1) | UniProt NCBI |
| ZNRD2 | Protein ZNRD2 (Autoantigen p27) (Sjoegren syndrome/scleroderma autoantigen 1) (Zinc ribbon domain-containing protein 2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-5545619 | 0.0499173803268 | 0.5 | TNKS | XAV939 inhibits tankyrase, stabilizing AXIN |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| TNKS | ZNRD2 | 0.856 | 0.793 | hein_WMM bioplex (ZNRD2) bioplex_WMM hein (TNKS) |
Images
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Complex HuMAP2_00575 has an average edge precision of 0.793 which is ranked 944 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| TNKS | HuMAP2_00575 HuMAP2_01652 HuMAP2_04190 HuMAP2_04552 |
| ZNRD2 | HuMAP2_00575 HuMAP2_01662 HuMAP2_04190 |