hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_00576
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| VTI1B | Vesicle transport through interaction with t-SNAREs homolog 1B (Vesicle transport v-SNARE protein Vti1-like 1) (Vti1-rp1) | UniProt NCBI |
| GOSR1 | Golgi SNAP receptor complex member 1 (28 kDa Golgi SNARE protein) (28 kDa cis-Golgi SNARE p28) (GOS-28) | UniProt NCBI |
| NAPB | Beta-soluble NSF attachment protein (SNAP-beta) (N-ethylmaleimide-sensitive factor attachment protein beta) | UniProt NCBI |
| NAPG | Gamma-soluble NSF attachment protein (SNAP-gamma) (N-ethylmaleimide-sensitive factor attachment protein gamma) | UniProt NCBI |
| NAPA | Alpha-soluble NSF attachment protein (SNAP-alpha) (N-ethylmaleimide-sensitive factor attachment protein alpha) | UniProt NCBI |
| GOSR2 | Golgi SNAP receptor complex member 2 (27 kDa Golgi SNARE protein) (Membrin) | UniProt NCBI |
| STX10 | Syntaxin-10 (Syn10) | UniProt NCBI |
| VAMP7 | Vesicle-associated membrane protein 7 (VAMP-7) (Synaptobrevin-like protein 1) (Tetanus-insensitive VAMP) (Ti-VAMP) | UniProt NCBI |
| STX12 | Syntaxin-12 | UniProt NCBI |
| VTI1A | Vesicle transport through interaction with t-SNAREs homolog 1A (Vesicle transport v-SNARE protein Vti1-like 2) (Vti1-rp2) | UniProt NCBI |
| VAMP8 | Vesicle-associated membrane protein 8 (VAMP-8) (Endobrevin) (EDB) | UniProt NCBI |
| STX6 | Syntaxin-6 | UniProt NCBI |
| VAMP4 | Vesicle-associated membrane protein 4 (VAMP-4) | UniProt NCBI |
| STX8 | Syntaxin-8 | UniProt NCBI |
| STX7 | Syntaxin-7 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0031201 | 5.95774637306e-31 | 0.933333333333 | VAMP8 VTI1B NAPA STX10 GOSR2 STX7 NAPG STX8 STX12 VTI1A STX6 VAMP7 NAPB GOSR1 | SNARE complex |
| KEGG:04130 | 4.68689672287e-26 | 0.733333333333 | VAMP8 VTI1B GOSR1 VAMP7 STX6 STX7 STX8 STX10 VAMP4 GOSR2 VTI1A | SNARE interactions in vesicular transport |
| GO:0061025 | 7.92340999726e-22 | 0.866666666667 | VTI1B NAPA STX10 GOSR2 STX7 NAPG STX8 VAMP4 STX12 VTI1A STX6 VAMP7 GOSR1 | membrane fusion |
| GO:0000149 | 2.14936268121e-20 | 0.8 | VTI1B NAPA STX10 GOSR2 STX7 NAPG STX8 STX12 NAPB STX6 VAMP7 VTI1A | SNARE binding |
| GO:0005484 | 3.03812220515e-20 | 0.666666666667 | VTI1B GOSR1 STX10 STX6 STX8 STX12 VTI1A GOSR2 VAMP7 STX7 | SNAP receptor activity |
| GO:0006906 | 1.01749847624e-18 | 0.733333333333 | VTI1B GOSR1 STX10 STX6 STX7 STX8 STX12 VAMP4 GOSR2 VAMP7 VTI1A | vesicle fusion |
| GO:0090174 | 2.61492780768e-18 | 0.733333333333 | VTI1B GOSR1 STX10 STX6 STX7 STX8 STX12 VAMP4 GOSR2 VAMP7 VTI1A | organelle membrane fusion |
| GO:0048284 | 3.74796752441e-17 | 0.733333333333 | VTI1B GOSR1 STX10 STX6 STX7 STX8 STX12 VAMP4 GOSR2 VAMP7 VTI1A | organelle fusion |
| GO:0016050 | 1.95441913693e-14 | 0.8 | VTI1B NAPA STX10 STX6 STX7 STX8 VAMP4 STX12 VTI1A GOSR2 VAMP7 GOSR1 | vesicle organization |
| GO:0061024 | 2.74333351598e-14 | 0.933333333333 | VAMP8 VTI1B NAPA STX10 GOSR2 STX7 NAPG STX8 VAMP4 STX12 VTI1A STX6 VAMP7 GOSR1 | membrane organization |
| REAC:R-HSA-6811438 | 2.02225741977e-12 | 0.466666666667 | NAPA GOSR2 NAPG VTI1A STX6 NAPB GOSR1 | Intra-Golgi traffic |
| GO:0098796 | 3.24399262183e-12 | 0.933333333333 | VAMP8 VTI1B NAPA STX10 GOSR2 STX7 NAPG STX8 STX12 VTI1A STX6 VAMP7 NAPB GOSR1 | membrane protein complex |
| REAC:R-HSA-6811440 | 3.31422856332e-12 | 0.466666666667 | NAPA STX6 NAPG STX10 VAMP4 VTI1A NAPB | Retrograde transport at the Trans-Golgi-Network |
| REAC:R-HSA-6811442 | 1.29625143315e-11 | 0.6 | NAPA GOSR2 NAPG VAMP4 STX10 VTI1A STX6 NAPB GOSR1 | Intra-Golgi and retrograde Golgi-to-ER traffic |
| GO:0016192 | 8.310891801e-11 | 1.0 | VAMP8 VTI1B NAPA STX10 GOSR2 STX7 NAPG STX8 VAMP4 STX12 VTI1A STX6 VAMP7 NAPB GOSR1 | vesicle-mediated transport |
| REAC:R-HSA-199991 | 9.23802156862e-11 | 0.733333333333 | VAMP8 NAPA VAMP7 GOSR2 NAPG VAMP4 STX10 VTI1A STX6 NAPB GOSR1 | Membrane Trafficking |
| CORUM:877 | 1.64753767118e-10 | 0.266666666667 | STX6 VTI1B VTI1A VAMP4 | SNARE complex (VAMP4, STX6, STX16, VTI1a, VTI1b) |
| REAC:R-HSA-5653656 | 1.66084428429e-10 | 0.733333333333 | VAMP8 NAPA VAMP7 GOSR2 NAPG VAMP4 STX10 VTI1A STX6 NAPB GOSR1 | Vesicle-mediated transport |
| GO:0098588 | 1.48678144458e-09 | 0.933333333333 | VAMP8 VTI1B NAPA STX10 GOSR2 STX7 NAPG VAMP4 STX12 VTI1A STX6 VAMP7 NAPB GOSR1 | bounding membrane of organelle |
| GO:0019905 | 1.73017634573e-09 | 0.466666666667 | NAPA STX6 STX8 NAPG STX10 NAPB STX7 | syntaxin binding |
| GO:0051640 | 2.59345717782e-09 | 0.733333333333 | VAMP8 VTI1B GOSR1 STX10 STX6 STX8 STX12 STX7 GOSR2 VAMP7 NAPA | organelle localization |
| GO:0046907 | 3.50875270914e-09 | 0.933333333333 | VAMP8 VTI1B NAPA STX10 GOSR2 STX7 NAPG STX8 STX12 VTI1A STX6 VAMP7 NAPB GOSR1 | intracellular transport |
| GO:0098805 | 8.21060820506e-09 | 0.866666666667 | VAMP8 VTI1B NAPA STX10 GOSR2 STX7 NAPG VAMP4 STX12 NAPB STX6 VAMP7 VTI1A | whole membrane |
| GO:0006891 | 9.68930642721e-09 | 0.4 | NAPA GOSR2 NAPG VTI1A VTI1B GOSR1 | intra-Golgi vesicle-mediated transport |
| GO:0030133 | 1.50668131279e-08 | 0.6 | VTI1B GOSR1 STX10 STX6 STX7 STX12 VAMP4 GOSR2 VTI1A | transport vesicle |
| GO:0051649 | 6.24799751877e-08 | 0.933333333333 | VAMP8 VTI1B NAPA STX10 GOSR2 STX7 NAPG STX8 STX12 VTI1A STX6 VAMP7 NAPB GOSR1 | establishment of localization in cell |
| GO:0048278 | 1.51584928274e-07 | 0.4 | STX10 VTI1B STX8 STX12 STX7 STX6 | vesicle docking |
| CORUM:874 | 1.63554364889e-07 | 0.2 | VAMP8 VAMP4 STX6 | SNARE complex (VAMP3, VAMP4, VAMP8, STX6) |
| GO:0071705 | 6.49974967615e-07 | 0.866666666667 | VAMP8 VTI1B NAPA STX10 GOSR2 STX7 NAPG STX8 STX12 NAPB STX6 VAMP7 VTI1A | nitrogen compound transport |
| GO:0005768 | 1.51616168562e-06 | 0.666666666667 | VAMP8 VTI1B VAMP7 STX6 STX7 STX8 STX12 VTI1A GOSR2 VAMP4 | endosome |
| GO:0031982 | 1.64333459694e-06 | 1.0 | VAMP8 VTI1B NAPA STX10 GOSR2 STX7 NAPG STX8 VAMP4 STX12 VTI1A STX6 VAMP7 NAPB GOSR1 | vesicle |
| GO:0016482 | 1.95776343978e-06 | 0.466666666667 | VTI1B GOSR1 STX6 STX8 STX10 VTI1A GOSR2 | cytosolic transport |
| GO:0140056 | 2.16012861864e-06 | 0.466666666667 | VAMP8 STX10 STX6 STX8 STX12 STX7 VTI1B | organelle localization by membrane tethering |
| GO:0006886 | 2.52954291515e-06 | 0.733333333333 | VTI1B NAPA STX10 GOSR2 STX7 NAPG STX8 STX12 NAPB STX6 VTI1A | intracellular protein transport |
| GO:0031090 | 2.72467236095e-06 | 0.933333333333 | VAMP8 VTI1B NAPA STX10 GOSR2 STX7 NAPG VAMP4 STX12 VTI1A STX6 VAMP7 NAPB GOSR1 | organelle membrane |
| GO:0051641 | 2.75772168356e-06 | 0.933333333333 | VAMP8 VTI1B NAPA STX10 GOSR2 STX7 NAPG STX8 STX12 VTI1A STX6 VAMP7 NAPB GOSR1 | cellular localization |
| GO:0022406 | 3.30736924178e-06 | 0.466666666667 | VAMP8 STX10 STX6 STX8 STX12 STX7 VTI1B | membrane docking |
| GO:0071702 | 4.42139347855e-06 | 0.866666666667 | VAMP8 VTI1B NAPA STX10 GOSR2 STX7 NAPG STX8 STX12 NAPB STX6 VAMP7 VTI1A | organic substance transport |
| GO:0005770 | 4.5271584796e-06 | 0.466666666667 | VAMP8 VAMP7 VTI1B STX8 VTI1A GOSR2 STX7 | late endosome |
| GO:0042147 | 5.15742219038e-06 | 0.4 | VTI1B GOSR1 STX6 STX10 VTI1A GOSR2 | retrograde transport, endosome to Golgi |
| GO:0019869 | 6.96822517242e-06 | 0.266666666667 | VAMP8 STX7 STX8 VTI1B | chloride channel inhibitor activity |
| REAC:R-HSA-6807878 | 8.09493377557e-06 | 0.333333333333 | GOSR2 NAPG NAPA GOSR1 NAPB | COPI-mediated anterograde transport |
| GO:0030659 | 9.13822181916e-06 | 0.6 | VAMP8 VTI1B VAMP7 STX10 STX6 STX12 VTI1A GOSR2 VAMP4 | cytoplasmic vesicle membrane |
| GO:0012506 | 1.17260016715e-05 | 0.6 | VAMP8 VTI1B VAMP7 STX10 STX6 STX12 VTI1A GOSR2 VAMP4 | vesicle membrane |
| GO:0048193 | 1.53700682381e-05 | 0.533333333333 | VAMP8 NAPA VAMP7 GOSR2 NAPG VTI1A VTI1B GOSR1 | Golgi vesicle transport |
| GO:0034613 | 1.94023019386e-05 | 0.8 | VAMP8 VTI1B NAPA STX10 GOSR2 STX7 NAPG STX8 STX12 NAPB STX6 VTI1A | cellular protein localization |
| GO:0070727 | 2.08024529674e-05 | 0.8 | VAMP8 VTI1B NAPA STX10 GOSR2 STX7 NAPG STX8 STX12 NAPB STX6 VTI1A | cellular macromolecule localization |
| GO:0017081 | 2.36830985232e-05 | 0.266666666667 | VAMP8 STX7 STX8 VTI1B | chloride channel regulator activity |
| GO:0030658 | 2.67588931373e-05 | 0.4 | STX10 STX6 GOSR2 STX12 VTI1A VTI1B | transport vesicle membrane |
| GO:0031410 | 2.7168322986e-05 | 0.8 | VAMP8 VTI1B GOSR1 STX10 STX6 STX7 STX8 STX12 VTI1A GOSR2 VAMP7 VAMP4 | cytoplasmic vesicle |
| GO:0006810 | 2.72325816878e-05 | 1.0 | VAMP8 VTI1B NAPA STX10 GOSR2 STX7 NAPG STX8 VAMP4 STX12 VTI1A STX6 VAMP7 NAPB GOSR1 | transport |
| GO:0097708 | 2.73738497027e-05 | 0.8 | VAMP8 VTI1B GOSR1 STX10 STX6 STX7 STX8 STX12 VTI1A GOSR2 VAMP7 VAMP4 | intracellular vesicle |
| GO:0030135 | 2.83466016238e-05 | 0.466666666667 | VAMP8 VAMP7 STX6 GOSR2 VTI1A VTI1B VAMP4 | coated vesicle |
| GO:0008021 | 2.9984842784e-05 | 0.4 | STX10 VTI1B STX12 VTI1A STX6 STX7 | synaptic vesicle |
| GO:0005773 | 3.06969653973e-05 | 0.6 | VAMP8 NAPA VAMP7 VTI1B STX7 NAPG VAMP4 VTI1A NAPB | vacuole |
| GO:0140029 | 4.1120473995e-05 | 0.333333333333 | VAMP7 VAMP8 VTI1B NAPB NAPA | exocytic process |
| GO:0005483 | 4.13224520905e-05 | 0.2 | NAPA NAPB NAPG | soluble NSF attachment protein activity |
| GO:0051234 | 4.23020690095e-05 | 1.0 | VAMP8 VTI1B NAPA STX10 GOSR2 STX7 NAPG STX8 VAMP4 STX12 VTI1A STX6 VAMP7 NAPB GOSR1 | establishment of localization |
| REAC:R-HSA-199977 | 5.88420304268e-05 | 0.333333333333 | GOSR2 NAPG NAPA GOSR1 NAPB | ER to Golgi Anterograde Transport |
| GO:0098791 | 6.06172630927e-05 | 0.466666666667 | GOSR1 VAMP7 STX6 STX8 STX10 VAMP4 VTI1A | Golgi subcompartment |
| GO:0070382 | 6.93918237641e-05 | 0.4 | STX10 VTI1B STX12 VTI1A STX6 STX7 | exocytic vesicle |
| GO:0031902 | 8.32140362253e-05 | 0.333333333333 | VAMP7 VAMP8 VTI1B VTI1A GOSR2 | late endosome membrane |
| REAC:R-HSA-204005 | 9.03302354917e-05 | 0.266666666667 | GOSR2 NAPA NAPB NAPG | COPII-mediated vesicle transport |
| GO:0030662 | 9.67635700828e-05 | 0.4 | VAMP8 VAMP7 VTI1B VAMP4 GOSR2 VTI1A | coated vesicle membrane |
| GO:0031984 | 0.000107637424584 | 0.466666666667 | GOSR1 VAMP7 STX6 STX8 STX10 VAMP4 VTI1A | organelle subcompartment |
| GO:0015031 | 0.000127464813253 | 0.733333333333 | VTI1B NAPA STX10 GOSR2 STX7 NAPG STX8 STX12 NAPB STX6 VTI1A | protein transport |
| GO:0044425 | 0.000129816035615 | 0.933333333333 | VAMP8 VTI1B NAPA STX10 GOSR2 STX7 NAPG STX8 STX12 VTI1A STX6 VAMP7 NAPB GOSR1 | membrane part |
| REAC:R-HSA-948021 | 0.000130539340167 | 0.333333333333 | GOSR2 NAPG NAPA GOSR1 NAPB | Transport to the Golgi and subsequent modification |
| CORUM:876 | 0.000140521514535 | 0.133333333333 | STX6 VTI1A | SNARE complex (VAMP3, STX6, VTI1A) |
| GO:0015833 | 0.00014844239014 | 0.733333333333 | VTI1B NAPA STX10 GOSR2 STX7 NAPG STX8 STX12 NAPB STX6 VTI1A | peptide transport |
| GO:0042886 | 0.000169800726889 | 0.733333333333 | VTI1B NAPA STX10 GOSR2 STX7 NAPG STX8 STX12 NAPB STX6 VTI1A | amide transport |
| GO:0045184 | 0.000287962642178 | 0.733333333333 | VTI1B NAPA STX10 GOSR2 STX7 NAPG STX8 STX12 NAPB STX6 VTI1A | establishment of protein localization |
| GO:0005774 | 0.000351536354654 | 0.466666666667 | VAMP8 NAPA VAMP7 VTI1B NAPG STX7 NAPB | vacuolar membrane |
| GO:0008104 | 0.000412350656102 | 0.8 | VAMP8 VTI1B NAPA STX10 GOSR2 STX7 NAPG STX8 STX12 NAPB STX6 VTI1A | protein localization |
| GO:0048280 | 0.000412725169389 | 0.2 | GOSR2 VTI1A VTI1B | vesicle fusion with Golgi apparatus |
| CORUM:1874 | 0.000467860031987 | 0.133333333333 | STX12 NAPB | SNARE complex (SNAP25, VAMP3, VAMP2, NAPB, STX13) |
| GO:0006888 | 0.00072356963545 | 0.4 | VAMP7 GOSR2 GOSR1 VTI1B VTI1A NAPA | endoplasmic reticulum to Golgi vesicle-mediated transport |
| GO:0098793 | 0.000747568758279 | 0.4 | STX10 VTI1B STX12 VTI1A STX6 STX7 | presynapse |
| GO:0008200 | 0.000779299415958 | 0.266666666667 | VAMP8 STX7 STX8 VTI1B | ion channel inhibitor activity |
| GO:0016248 | 0.000898659795414 | 0.266666666667 | VAMP8 STX7 STX8 VTI1B | channel inhibitor activity |
| GO:0005802 | 0.00109085259865 | 0.4 | VAMP7 STX6 STX8 STX10 VTI1A VAMP4 | trans-Golgi network |
| GO:0006892 | 0.00121694160594 | 0.333333333333 | VAMP7 VAMP8 VTI1B VTI1A GOSR2 | post-Golgi vesicle-mediated transport |
| GO:0016197 | 0.00123077381754 | 0.4 | VTI1B GOSR1 STX6 STX10 VTI1A GOSR2 | endosomal transport |
| GO:0048471 | 0.00133644398076 | 0.466666666667 | VAMP8 VTI1B STX8 STX10 VTI1A STX6 STX7 | perinuclear region of cytoplasm |
| GO:0033036 | 0.00140507252341 | 0.8 | VAMP8 VTI1B NAPA STX10 GOSR2 STX7 NAPG STX8 STX12 NAPB STX6 VTI1A | macromolecule localization |
| GO:0051179 | 0.00147534621948 | 1.0 | VAMP8 VTI1B NAPA STX10 GOSR2 STX7 NAPG STX8 VAMP4 STX12 VTI1A STX6 VAMP7 NAPB GOSR1 | localization |
| GO:0060341 | 0.00151399526974 | 0.533333333333 | VAMP8 NAPA VAMP7 VTI1B STX7 STX8 NAPB GOSR1 | regulation of cellular localization |
| GO:0016043 | 0.00164433273797 | 1.0 | VAMP8 VTI1B NAPA STX10 GOSR2 STX7 NAPG STX8 VAMP4 STX12 VTI1A STX6 VAMP7 NAPB GOSR1 | cellular component organization |
| GO:0044431 | 0.00165891745753 | 0.533333333333 | GOSR1 VAMP7 STX6 STX8 STX10 VAMP4 GOSR2 VTI1A | Golgi apparatus part |
| REAC:R-HSA-446203 | 0.00170874716426 | 0.333333333333 | GOSR2 NAPG NAPA GOSR1 NAPB | Asparagine N-linked glycosylation |
| GO:0071840 | 0.00270285140848 | 1.0 | VAMP8 VTI1B NAPA STX10 GOSR2 STX7 NAPG STX8 VAMP4 STX12 VTI1A STX6 VAMP7 NAPB GOSR1 | cellular component organization or biogenesis |
| GO:0055037 | 0.00421451513409 | 0.333333333333 | STX12 VTI1B STX7 STX8 VAMP8 | recycling endosome |
| GO:0044437 | 0.00490836175354 | 0.466666666667 | VAMP8 NAPA VAMP7 VTI1B NAPG STX7 NAPB | vacuolar part |
| GO:0030285 | 0.00493775244894 | 0.2 | STX12 STX10 STX6 | integral component of synaptic vesicle membrane |
| REAC:R-HSA-432722 | 0.00534317868235 | 0.2 | VAMP8 NAPA VAMP7 | Golgi Associated Vesicle Biogenesis |
| GO:0030136 | 0.00607426704128 | 0.333333333333 | VAMP4 VAMP8 VAMP7 VTI1A STX6 | clathrin-coated vesicle |
| GO:0044433 | 0.00661146447452 | 0.6 | VAMP8 VTI1B VAMP7 STX10 STX6 STX12 VTI1A GOSR2 VAMP4 | cytoplasmic vesicle part |
| GO:0099503 | 0.00712307523545 | 0.533333333333 | VAMP8 VAMP7 STX10 STX6 STX12 VTI1A VTI1B STX7 | secretory vesicle |
| GO:0005794 | 0.0076644537056 | 0.6 | VTI1B GOSR1 VAMP7 STX6 STX8 STX10 VAMP4 GOSR2 VTI1A | Golgi apparatus |
| GO:0090161 | 0.0117469826046 | 0.2 | STX6 VTI1A VAMP4 | Golgi ribbon formation |
| REAC:R-HSA-199992 | 0.0127082510208 | 0.2 | VAMP8 NAPA VAMP7 | trans-Golgi Network Vesicle Budding |
| GO:0032991 | 0.0139875206848 | 0.933333333333 | VAMP8 VTI1B NAPA STX10 GOSR2 STX7 NAPG STX8 STX12 VTI1A STX6 VAMP7 NAPB GOSR1 | protein-containing complex |
| GO:0006896 | 0.0149416678413 | 0.2 | GOSR2 VTI1A VTI1B | Golgi to vacuole transport |
| GO:0098563 | 0.0149416678413 | 0.2 | STX12 STX10 STX6 | intrinsic component of synaptic vesicle membrane |
| GO:0051588 | 0.0204199848995 | 0.266666666667 | VAMP8 VAMP7 NAPB NAPA | regulation of neurotransmitter transport |
| HPA:008030_23 | 0.0220529064112 | 0.4 | VAMP7 VTI1B STX8 STX12 STX6 NAPA | cerebral cortex; neuronal cells[Approved,High] |
| REAC:R-HSA-8856825 | 0.0239508417776 | 0.2 | VAMP8 VAMP4 VAMP7 | Cargo recognition for clathrin-mediated endocytosis |
| KEGG:00000 | 0.0252253336476 | 0.866666666667 | VAMP8 VTI1B NAPA STX10 GOSR2 STX7 STX8 VAMP4 STX12 VTI1A STX6 VAMP7 GOSR1 | KEGG root term |
| GO:0099106 | 0.029363021586 | 0.266666666667 | VAMP8 STX7 STX8 VTI1B | ion channel regulator activity |
| REAC:R-HSA-6811434 | 0.0300062332216 | 0.2 | NAPA NAPB NAPG | COPI-dependent Golgi-to-ER retrograde traffic |
| GO:0016020 | 0.0303801371308 | 1.0 | VAMP8 VTI1B NAPA STX10 GOSR2 STX7 NAPG STX8 VAMP4 STX12 VTI1A STX6 VAMP7 NAPB GOSR1 | membrane |
| GO:1903076 | 0.0347944359492 | 0.266666666667 | VAMP8 STX7 STX8 VTI1B | regulation of protein localization to plasma membrane |
| GO:1903305 | 0.0347944359492 | 0.266666666667 | VAMP8 VAMP7 NAPB NAPA | regulation of regulated secretory pathway |
| HPA:032020_22 | 0.046084494044 | 0.533333333333 | NAPA STX10 STX6 STX8 STX12 NAPB VTI1B VAMP7 | pancreas; islets of Langerhans[Approved,Medium] |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| STX12 | GOSR1 | 0.994 | 0.923 | hein_WMM bioplex (STX12) bioplex_WMM gupta_WMM |
| GOSR1 | STX7 | 0.992 | 0.913 | hein_WMM bioplex (STX7) bioplex_WMM youn_WMM gupta_WMM |
| STX12 | STX10 | 0.894 | 0.82 | bioplex (STX12) bioplex_WMM gupta_WMM |
| STX8 | STX7 | 0.84 | 0.784 | hein_WMM bioplex (STX7) bioplex_WMM youn_WMM gupta_WMM |
| STX12 | VTI1A | 0.744 | 0.74 | bioplex (STX12) bioplex_WMM gupta_WMM |
| STX12 | VAMP8 | 0.711 | 0.728 | bioplex (STX12) bioplex_WMM gupta_WMM |
| GOSR2 | STX7 | 0.618 | 0.674 | bioplex (STX7) bioplex_WMM youn_WMM gupta_WMM |
| STX12 | NAPA | 0.558 | 0.649 | bioplex (STX12) bioplex_WMM |
| STX6 | STX10 | 0.52 | 0.632 | hein_WMM bioplex (STX6) bioplex_WMM gupta_WMM |
| STX12 | NAPB | 0.507 | 0.628 | bioplex (STX12) bioplex_WMM |
| VAMP4 | STX7 | 0.474 | 0.609 | bioplex (STX7,VAMP4) bioplex_WMM youn_WMM gupta_WMM |
| GOSR2 | STX6 | 0.46 | 0.598 | bioplex (STX6) bioplex_WMM gupta_WMM |
| STX8 | VTI1B | 0.429 | 0.577 | hein_WMM bioplex (VTI1B) bioplex_WMM |
| STX10 | STX7 | 0.377 | 0.548 | hein_WMM bioplex (STX7) bioplex_WMM gupta_WMM |
| STX12 | STX8 | 0.356 | 0.539 | bioplex (STX12) bioplex_WMM gupta_WMM |
| STX12 | STX6 | 0.342 | 0.53 | bioplex (STX12,STX6) bioplex_WMM gupta_WMM |
| STX6 | STX7 | 0.247 | 0.47 | hein_WMM bioplex (STX6,STX7) bioplex_WMM gupta_WMM |
| GOSR1 | STX6 | 0.202 | 0.451 | bioplex (STX6) bioplex_WMM gupta_WMM |
| STX12 | GOSR2 | 0.166 | 0.423 | bioplex (STX12) bioplex_WMM gupta_WMM |
| STX12 | VAMP4 | 0.152 | 0.409 | bioplex (STX12,VAMP4) bioplex_WMM gupta_WMM |
| VAMP8 | STX7 | 0.14 | 0.406 | hein_WMM bioplex (STX7) bioplex_WMM gupta_WMM |
| NAPB | VAMP4 | 0.13 | 0.401 | bioplex (VAMP4) bioplex_WMM |
| VAMP4 | STX8 | 0.128 | 0.398 | bioplex (VAMP4) bioplex_WMM youn_WMM gupta_WMM |
| STX12 | VTI1B | 0.124 | 0.395 | bioplex (STX12,VTI1B) bioplex_WMM |
| NAPA | VTI1B | 0.115 | 0.384 | bioplex (VTI1B) bioplex_WMM |
| VAMP8 | STX6 | 0.114 | 0.385 | hein_WMM bioplex (STX6) bioplex_WMM gupta_WMM |
| NAPG | STX7 | 0.092 | 0.355 | bioplex (NAPG,STX7) bioplex_WMM |
| VTI1B | STX7 | 0.084 | 0.349 | hein_WMM bioplex (STX7,VTI1B) bioplex_WMM |
| STX12 | VAMP7 | 0.079 | 0.353 | bioplex (STX12) bioplex_WMM gupta_WMM |
| VTI1A | STX6 | 0.072 | 0.355 | hein_WMM bioplex (STX6) bioplex_WMM gupta_WMM |
| VAMP4 | STX10 | 0.067 | 0.351 | bioplex (VAMP4) bioplex_WMM gupta_WMM |
| NAPG | VTI1B | 0.064 | 0.35 | bioplex (NAPG,VTI1B) bioplex_WMM |
| STX12 | NAPG | 0.064 | 0.349 | bioplex (NAPG,STX12) bioplex_WMM |
| VTI1A | STX7 | 0.057 | 0.324 | hein_WMM bioplex (STX7) bioplex_WMM gupta_WMM |
| NAPG | STX8 | 0.053 | 0.301 | bioplex (NAPG) bioplex_WMM |
| STX6 | STX8 | 0.044 | 0.28 | hein_WMM bioplex (STX6) bioplex_WMM gupta_WMM |
| NAPA | VAMP4 | 0.043 | 0.269 | bioplex (VAMP4) bioplex_WMM |
| STX6 | VAMP4 | 0.042 | 0.27 | bioplex (VAMP4) bioplex_WMM gupta_WMM |
| VTI1A | VAMP4 | 0.034 | 0.259 | bioplex (VAMP4) bioplex_WMM gupta_WMM |
| STX6 | VTI1B | 0.025 | 0.217 | hein_WMM bioplex (STX6,VTI1B) bioplex_WMM |
| NAPG | STX6 | 0.025 | 0.215 | bioplex (STX6) bioplex_WMM |
| VAMP4 | VTI1B | 0.025 | 0.211 | bioplex (VAMP4) bioplex_WMM |
| GOSR1 | GOSR2 | 0.023 | 0.207 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| GOSR1 | VAMP4 | 0.023 | 0.206 | bioplex (VAMP4) bioplex_WMM youn_WMM gupta_WMM |
| GOSR1 | STX10 | 0.023 | 0.211 | hein_WMM bioplex_WMM gupta_WMM WMM_only |
| NAPA | STX7 | 0.021 | 0.194 | bioplex (STX7) bioplex_WMM treiber_WMM |
| VAMP8 | STX8 | 0.019 | 0.185 | hein_WMM bioplex_WMM gupta_WMM WMM_only |
| NAPG | NAPA | 0.019 | 0.185 | bioplex (NAPG) bioplex_WMM |
| VTI1A | GOSR2 | 0.017 | 0.175 | bioplex_WMM gupta_WMM WMM_only |
| STX10 | STX8 | 0.017 | 0.174 | hein_WMM bioplex_WMM gupta_WMM WMM_only |
| GOSR1 | STX8 | 0.017 | 0.171 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| GOSR2 | VAMP4 | 0.016 | 0.158 | bioplex (VAMP4) bioplex_WMM youn_WMM gupta_WMM |
| VAMP8 | VTI1B | 0.015 | 0.147 | hein_WMM bioplex_WMM WMM_only |
| GOSR2 | STX10 | 0.015 | 0.142 | bioplex_WMM gupta_WMM WMM_only |
| VTI1A | STX10 | 0.015 | 0.14 | hein_WMM bioplex_WMM gupta_WMM WMM_only |
| GOSR1 | VTI1A | 0.014 | 0.145 | bioplex_WMM gupta_WMM WMM_only |
| GOSR2 | STX8 | 0.014 | 0.143 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| STX10 | VTI1B | 0.013 | 0.143 | hein_WMM bioplex (VTI1B) bioplex_WMM |
| VTI1A | VTI1B | 0.013 | 0.152 | hein_WMM bioplex_WMM WMM_only |
| VTI1A | STX8 | 0.013 | 0.147 | hein_WMM bioplex_WMM gupta_WMM WMM_only |
| VAMP8 | VAMP4 | 0.012 | 0.146 | bioplex_WMM gupta_WMM WMM_only |
| VTI1A | VAMP8 | 0.012 | 0.144 | hein_WMM bioplex_WMM gupta_WMM WMM_only |
| GOSR2 | VTI1B | 0.012 | 0.15 | bioplex_WMM WMM_only |
| VAMP8 | STX10 | 0.012 | 0.15 | hein_WMM bioplex_WMM gupta_WMM WMM_only |
| NAPG | STX10 | 0.012 | 0.15 | bioplex_WMM WMM_only |
| NAPG | GOSR2 | 0.011 | 0.143 | bioplex_WMM WMM_only |
| STX12 | STX7 | 0.011 | 0.145 | bioplex (STX12,STX7) bioplex_WMM gupta_WMM |
| VTI1A | NAPG | 0.011 | 0.145 | bioplex_WMM WMM_only |
| GOSR1 | VAMP8 | 0.011 | 0.144 | bioplex_WMM gupta_WMM WMM_only |
| STX10 | VAMP7 | 0.01 | 0.116 | bioplex_WMM gupta_WMM WMM_only |
| VAMP8 | GOSR2 | 0.009 | 0.112 | bioplex_WMM gupta_WMM WMM_only |
| GOSR1 | NAPG | 0.009 | 0.11 | bioplex_WMM WMM_only |
| NAPA | STX6 | 0.008 | 0.085 | bioplex (STX6) bioplex_WMM |
| NAPB | VTI1A | 0.008 | 0.085 | bioplex_WMM WMM_only |
| NAPB | NAPG | 0.008 | 0.09 | bioplex_WMM WMM_only |
| GOSR1 | VTI1B | 0.008 | 0.092 | hein_WMM bioplex_WMM WMM_only |
| NAPB | GOSR2 | 0.008 | 0.086 | bioplex_WMM WMM_only |
| VAMP4 | VAMP7 | 0.008 | 0.073 | bioplex_WMM gupta_WMM WMM_only |
| NAPG | VAMP8 | 0.008 | 0.068 | bioplex_WMM WMM_only |
| VAMP8 | VAMP7 | 0.008 | 0.04 | bioplex_WMM gupta_WMM WMM_only |
| NAPB | STX6 | 0.008 | 0.034 | bioplex_WMM WMM_only |
| STX6 | VAMP7 | 0.008 | 0.033 | bioplex (STX6) bioplex_WMM gupta_WMM |
| GOSR1 | NAPB | 0.008 | 0.029 | bioplex_WMM WMM_only |
| VTI1A | NAPA | 0.008 | 0.024 | bioplex_WMM WMM_only |
| NAPA | GOSR2 | 0.008 | 0.024 | bioplex_WMM WMM_only |
| NAPB | STX10 | 0.008 | 0.023 | bioplex_WMM WMM_only |
| VTI1A | VAMP7 | 0.007 | 0.006 | bioplex_WMM gupta_WMM WMM_only |
| GOSR2 | VAMP7 | 0.007 | 0.009 | bioplex_WMM gupta_WMM WMM_only |
| NAPB | VAMP8 | 0.007 | 0.006 | bioplex_WMM WMM_only |
| NAPB | STX7 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| NAPB | STX8 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| GOSR1 | VAMP7 | 0.007 | 0.003 | bioplex_WMM gupta_WMM WMM_only |
| NAPB | VTI1B | 0.007 | 0.005 | bioplex_WMM WMM_only |
| NAPA | VAMP8 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| NAPA | STX10 | 0.007 | 0.001 | bioplex_WMM WMM_only |
| NAPB | NAPA | 0.007 | 0.005 | bioplex_WMM WMM_only |
| NAPB | VAMP7 | 0.007 | 0.001 | bioplex_WMM WMM_only |
| GOSR1 | NAPA | 0.007 | 0.005 | bioplex_WMM WMM_only |
| NAPA | STX8 | 0.006 | 0.002 | bioplex_WMM WMM_only |
| NAPG | VAMP4 | 0.006 | 0.008 | bioplex (NAPG,VAMP4) bioplex_WMM |
| NAPG | VAMP7 | 0.006 | 0.008 | bioplex_WMM WMM_only |
| STX8 | VAMP7 | 0.006 | 0.011 | bioplex_WMM gupta_WMM WMM_only |
| STX7 | VAMP7 | 0.005 | 0.008 | bioplex (STX7) bioplex_WMM gupta_WMM |
| VTI1B | VAMP7 | 0.005 | 0.008 | bioplex_WMM WMM_only |
| NAPA | VAMP7 | 0.004 | 0.008 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_00576 has an average edge precision of 0.242 which is ranked 5495 out of all 6965 complexes.
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