hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00577
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NPTN | Neuroplastin (Stromal cell-derived receptor 1) (SDR-1) | UniProt NCBI |
| GCLC | Glutamate--cysteine ligase catalytic subunit (EC 6.3.2.2) (GCS heavy chain) (Gamma-ECS) (Gamma-glutamylcysteine synthetase) | UniProt NCBI |
| TNFAIP8L2 | Tumor necrosis factor alpha-induced protein 8-like protein 2 (TIPE2) (TNF alpha-induced protein 8-like protein 2) (TNFAIP8-like protein 2) (Inflammation factor protein 20) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP4518 | 0.0428416541517 | 0.333333333333 | GCLC | Gamma-Glutamyl Cycle for the biosynthesis and degradation of glutathione, including diseases |
| CORUM:7186 | 0.0499776345577 | 0.333333333333 | GCLC | Glutamate-cysteine ligase |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| NPTN | TNFAIP8L2 | 0.02 | 0.185 | bioplex (TNFAIP8L2) bioplex_WMM |
| NPTN | GCLC | 0.02 | 0.184 | fraction |
Images
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Complex HuMAP2_00577 has an average edge precision of 0.184 which is ranked 6385 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NPTN | HuMAP2_00577 HuMAP2_02798 HuMAP2_03115 |
| GCLC | HuMAP2_00577 HuMAP2_01476 HuMAP2_02320 HuMAP2_03115 HuMAP2_03161 HuMAP2_05215 HuMAP2_05459 |
| TNFAIP8L2 | HuMAP2_00577 HuMAP2_02798 HuMAP2_03115 |