hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00585
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MORF4L1 | Mortality factor 4-like protein 1 (MORF-related gene 15 protein) (Protein MSL3-1) (Transcription factor-like protein MRG15) | UniProt NCBI |
| KDM5A | Lysine-specific demethylase 5A (EC 1.14.11.-) (Histone demethylase JARID1A) (Jumonji/ARID domain-containing protein 1A) (Retinoblastoma-binding protein 2) (RBBP-2) | UniProt NCBI |
| MRFAP1 | MORF4 family-associated protein 1 (Protein PGR1) (Protein associated with MRG of 14 kDa) | UniProt NCBI |
| EMSY | BRCA2-interacting transcriptional repressor EMSY | UniProt NCBI |
| PALB2 | Partner and localizer of BRCA2 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:722 | 2.0123342217e-05 | 0.4 | MRFAP1 MORF4L1 | MRG15-PAM14-RB complex |
| CORUM:723 | 2.0123342217e-05 | 0.4 | MRFAP1 MORF4L1 | MRG15-PAM14-RB complex |
| CORUM:724 | 0.0499494897235 | 0.2 | MORF4L1 | MAF2 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| MRFAP1 | MORF4L1 | 0.941 | 0.854 | bioplex (MORF4L1) bioplex_WMM |
| PALB2 | MORF4L1 | 0.925 | 0.843 | bioplex (MORF4L1) bioplex_WMM |
| KDM5A | MORF4L1 | 0.923 | 0.844 | hein_WMM bioplex (MORF4L1) bioplex_WMM |
| EMSY | MORF4L1 | 0.561 | 0.65 | hein_WMM bioplex (MORF4L1) bioplex_WMM |
| KDM5A | EMSY | 0.104 | 0.37 | hein_WMM bioplex_WMM hein (KDM5A) |
| MRFAP1 | PALB2 | 0.011 | 0.14 | bioplex_WMM WMM_only |
| PALB2 | EMSY | 0.009 | 0.09 | bioplex_WMM youn_WMM WMM_only |
| KDM5A | PALB2 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| MRFAP1 | EMSY | 0.009 | 0.097 | bioplex_WMM WMM_only |
| MRFAP1 | KDM5A | 0.009 | 0.097 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_00585 has an average edge precision of 0.408 which is ranked 3219 out of all 6965 complexes.
Related Complexes