hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00587
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CDK12 | Cyclin-dependent kinase 12 (EC 2.7.11.22) (EC 2.7.11.23) (Cdc2-related kinase, arginine/serine-rich) (CrkRS) (Cell division cycle 2-related protein kinase 7) (CDC2-related protein kinase 7) (Cell division protein kinase 12) (hCDK12) | UniProt NCBI |
| SCAF4 | SR-related and CTD-associated factor 4 (CTD-binding SR-like protein RA4) (Splicing factor, arginine/serine-rich 15) | UniProt NCBI |
| CCNK | Cyclin-K | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0002944 | 0.00135247023414 | 0.666666666667 | CCNK CDK12 | cyclin K-CDK12 complex |
| REAC:R-HSA-6796648 | 0.0126269885924 | 0.666666666667 | CCNK CDK12 | TP53 Regulates Transcription of DNA Repair Genes |
| CORUM:1083 | 0.0499776345577 | 0.333333333333 | CCNK | P-TEFb.4 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CCNK | CDK12 | 0.424 | 0.575 | hein_WMM bioplex_WMM Guru youn_WMM gupta_WMM fraction |
| CDK12 | SCAF4 | 0.164 | 0.42 | bioplex_WMM youn_WMM gupta_WMM fraction |
| CCNK | SCAF4 | 0.006 | 0.002 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
Images
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Complex HuMAP2_00587 has an average edge precision of 0.332 which is ranked 4206 out of all 6965 complexes.
Related Complexes