hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00594
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ANP32A | Acidic leucine-rich nuclear phosphoprotein 32 family member A (Acidic nuclear phosphoprotein pp32) (pp32) (Leucine-rich acidic nuclear protein) (LANP) (Mapmodulin) (Potent heat-stable protein phosphatase 2A inhibitor I1PP2A) (Putative HLA-DR-associated protein I) (PHAPI) | UniProt NCBI |
| REPIN1 | Replication initiator 1 (60 kDa origin-specific DNA-binding protein) (60 kDa replication initiation region protein) (ATT-binding protein) (DHFR oribeta-binding protein RIP60) (Zinc finger protein 464) | UniProt NCBI |
| SET | Protein SET (HLA-DR-associated protein II) (Inhibitor of granzyme A-activated DNase) (IGAAD) (PHAPII) (Phosphatase 2A inhibitor I2PP2A) (I-2PP2A) (Template-activating factor I) (TAF-I) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-450520 | 0.000140571869389 | 0.666666666667 | SET ANP32A | HuR (ELAVL1) binds and stabilizes mRNA |
| MIRNA:hsa-miR-3936 | 0.0138764847068 | 0.666666666667 | SET REPIN1 | hsa-miR-3936 |
| REAC:R-HSA-450531 | 0.0232544758505 | 0.666666666667 | SET ANP32A | Regulation of mRNA stability by proteins that bind AU-rich elements |
| MIRNA:hsa-miR-374a-3p | 0.0243005432667 | 0.666666666667 | SET ANP32A | hsa-miR-374a-3p |
| CORUM:5153 | 0.0499776345577 | 0.333333333333 | SET | CTFC-TAF1 complex |
| CORUM:6989 | 0.0499776345577 | 0.333333333333 | SET | ProTalpha C9 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ANP32A | SET | 0.988 | 0.901 | boldt gupta_WMM fraction boldt_WMM |
| REPIN1 | SET | 0.92 | 0.844 | hein_WMM bioplex (REPIN1,SET) bioplex_WMM youn_WMM hein (SET) |
Images
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Complex HuMAP2_00594 has an average edge precision of 0.873 which is ranked 682 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ANP32A | HuMAP2_00594 HuMAP2_01842 HuMAP2_03625 HuMAP2_06511 |
| REPIN1 | HuMAP2_00594 HuMAP2_05087 HuMAP2_05104 HuMAP2_06186 HuMAP2_06511 |
| SET | HuMAP2_00594 HuMAP2_01842 HuMAP2_03625 HuMAP2_05220 HuMAP2_06511 |