hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00623
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| MINDY1 | Ubiquitin carboxyl-terminal hydrolase MINDY-1 (EC 3.4.19.12) (Deubiquitinating enzyme MINDY-1) (Protein FAM63A) | UniProt NCBI |
| TAX1BP1 | Tax1-binding protein 1 (TRAF6-binding protein) | UniProt NCBI |
| FHL5 | Four and a half LIM domains protein 5 (FHL-5) (Activator of cAMP-responsive element modulator in testis) (Activator of CREM in testis) | UniProt NCBI |
| CEP76 | Centrosomal protein of 76 kDa (Cep76) | UniProt NCBI |
| RNF126 | E3 ubiquitin-protein ligase RNF126 (EC 2.3.2.27) (RING finger protein 126) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:3185 | 0.0249780992026 | 0.2 | FHL5 | ACT homodimer complex |
| CORUM:3188 | 0.0499494897235 | 0.2 | FHL5 | FHL2-ACT complex |
| CORUM:3191 | 0.0499494897235 | 0.2 | FHL5 | ACT-CREB complex |
| CORUM:3196 | 0.0499494897235 | 0.2 | FHL5 | FHL4/STX11-ACT complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| FHL5 | CEP76 | 0.611 | 0.674 | bioplex (FHL5) |
| TAX1BP1 | FHL5 | 0.103 | 0.366 | bioplex (FHL5) |
| MINDY1 | RNF126 | 0.035 | 0.265 | bioplex (RNF126) bioplex_WMM |
| TAX1BP1 | RNF126 | 0.033 | 0.25 | bioplex (RNF126) bioplex_WMM |
| TAX1BP1 | CEP76 | 0.008 | 0.011 | bioplex_WMM WMM_only |
| TAX1BP1 | MINDY1 | 0.007 | 0.006 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_00623 has an average edge precision of 0.262 which is ranked 5198 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| MINDY1 | HuMAP2_00623 HuMAP2_04160 HuMAP2_07011 |
| TAX1BP1 | HuMAP2_00347 HuMAP2_00623 HuMAP2_06282 |
| FHL5 | HuMAP2_00623 HuMAP2_04414 HuMAP2_06282 |
| CEP76 | HuMAP2_00623 HuMAP2_04414 HuMAP2_06282 |
| RNF126 | HuMAP2_00623 HuMAP2_02451 HuMAP2_02753 HuMAP2_03193 HuMAP2_04160 HuMAP2_07011 |