hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00629
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CETN2 | Centrin-2 (Caltractin isoform 1) | UniProt NCBI |
| NINL | Ninein-like protein | UniProt NCBI |
| LRRC39 | Leucine-rich repeat-containing protein 39 (Myosin-interacting M-band-associated stress-responsive protein) (Myomasp) | UniProt NCBI |
| POC5 | Centrosomal protein POC5 (Protein of centriole 5) (hPOC5) | UniProt NCBI |
| CETN3 | Centrin-3 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-380259 | 0.0295837500362 | 0.4 | NINL CETN2 | Loss of Nlp from mitotic centrosomes |
| REAC:R-HSA-380284 | 0.0295837500362 | 0.4 | NINL CETN2 | Loss of proteins required for interphase microtubule organization from the centrosome |
| REAC:R-HSA-8854518 | 0.0323002764482 | 0.4 | NINL CETN2 | AURKA Activation by TPX2 |
| REAC:R-HSA-380287 | 0.0411580285567 | 0.4 | NINL CETN2 | Centrosome maturation |
| REAC:R-HSA-380270 | 0.0411580285567 | 0.4 | NINL CETN2 | Recruitment of mitotic centrosome proteins and complexes |
| GO:0070390 | 0.0450641792523 | 0.4 | CETN3 CETN2 | transcription export complex 2 |
| REAC:R-HSA-2565942 | 0.0465369402216 | 0.4 | NINL CETN2 | Regulation of PLK1 Activity at G2/M Transition |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| LRRC39 | CETN2 | 0.558 | 0.649 | bioplex (LRRC39) bioplex_WMM |
| LRRC39 | NINL | 0.297 | 0.497 | bioplex (LRRC39) bioplex_WMM |
| CETN2 | POC5 | 0.124 | 0.395 | hein_WMM bioplex (POC5) bioplex_WMM hein (CETN2) gupta (CETN2,POC5) |
| CETN2 | CETN3 | 0.104 | 0.37 | hein_WMM bioplex_WMM hein (CETN2) gupta_WMM |
| POC5 | CETN3 | 0.021 | 0.186 | hein_WMM bioplex (POC5) bioplex_WMM youn_WMM gupta (POC5) |
| CETN2 | NINL | 0.007 | 0.006 | bioplex_WMM WMM_only |
| POC5 | NINL | 0.004 | 0.016 | gupta_WMM gupta (NINL) |
Images
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Complex HuMAP2_00629 has an average edge precision of 0.303 which is ranked 4542 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CETN2 | HuMAP2_00629 HuMAP2_01838 HuMAP2_03913 HuMAP2_03958 HuMAP2_04053 |
| NINL | HuMAP2_00629 HuMAP2_03766 HuMAP2_04354 HuMAP2_04639 |
| LRRC39 | HuMAP2_00629 HuMAP2_01382 HuMAP2_03259 HuMAP2_04639 HuMAP2_05576 |
| POC5 | HuMAP2_00629 HuMAP2_01838 HuMAP2_03913 HuMAP2_06724 |
| CETN3 | HuMAP2_00629 HuMAP2_01838 HuMAP2_03913 HuMAP2_04053 |