hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00645
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| NR1H4 | Bile acid receptor (Farnesoid X-activated receptor) (Farnesol receptor HRR-1) (Nuclear receptor subfamily 1 group H member 4) (Retinoid X receptor-interacting protein 14) (RXR-interacting protein 14) | UniProt NCBI |
| RXRB | Retinoic acid receptor RXR-beta (Nuclear receptor subfamily 2 group B member 2) (Retinoid X receptor beta) | UniProt NCBI |
| FLYWCH2 | FLYWCH family member 2 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-1989781 | 0.0370864129386 | 0.666666666667 | RXRB NR1H4 | PPARA activates gene expression |
| REAC:R-HSA-400206 | 0.037791121028 | 0.666666666667 | RXRB NR1H4 | Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) |
| CORUM:5367 | 0.0499776345577 | 0.333333333333 | RXRB | THRB-RXRB complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RXRB | FLYWCH2 | 0.13 | 0.399 | bioplex (FLYWCH2) bioplex_WMM |
| RXRB | NR1H4 | 0.047 | 0.291 | bioplex (NR1H4) bioplex_WMM |
Images
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Complex HuMAP2_00645 has an average edge precision of 0.345 which is ranked 4058 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| NR1H4 | HuMAP2_00645 HuMAP2_05219 |
| RXRB | HuMAP2_00645 HuMAP2_05219 |
| FLYWCH2 | HuMAP2_00645 HuMAP2_05219 |