hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00652
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| DIDO1 | Death-inducer obliterator 1 (DIO-1) (hDido1) (Death-associated transcription factor 1) (DATF-1) | UniProt NCBI |
| KLHDC3 | Kelch domain-containing protein 3 (Protein Peas) (Testis intracellular mediator protein) | UniProt NCBI |
| BRAP | BRCA1-associated protein (EC 2.3.2.27) (BRAP2) (Impedes mitogenic signal propagation) (IMP) (RING finger protein 52) (RING-type E3 ubiquitin transferase BRAP2) (Renal carcinoma antigen NY-REN-63) | UniProt NCBI |
| RIF1 | Telomere-associated protein RIF1 (Rap1-interacting factor 1 homolog) | UniProt NCBI |
| CUL2 | Cullin-2 (CUL-2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| MIRNA:hsa-miR-93-3p | 0.0142310277096 | 0.6 | KLHDC3 DIDO1 CUL2 | hsa-miR-93-3p |
| CORUM:6736 | 0.0499494897235 | 0.2 | CUL2 | PRAME-Cullin2 ubiquitin ligase complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CUL2 | KLHDC3 | 0.886 | 0.817 | bioplex (KLHDC3) bioplex_WMM boldt boldt_WMM |
| KLHDC3 | BRAP | 0.831 | 0.778 | bioplex (KLHDC3) bioplex_WMM |
| DIDO1 | KLHDC3 | 0.073 | 0.355 | bioplex () bioplex_WMM |
| DIDO1 | RIF1 | 0.068 | 0.348 | youn_WMM fraction treiber_WMM |
| DIDO1 | BRAP | 0.008 | 0.039 | youn_WMM WMM_only bioplex_WMM |
| CUL2 | BRAP | 0.007 | 0.008 | bioplex_WMM WMM_only |
| CUL2 | DIDO1 | 0.007 | 0.006 | WMM_only bioplex_WMM |
| RIF1 | BRAP | 0.007 | 0.006 | youn_WMM WMM_only |
Images
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Complex HuMAP2_00652 has an average edge precision of 0.295 which is ranked 4680 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| DIDO1 | HuMAP2_00652 |
| KLHDC3 | HuMAP2_00652 HuMAP2_00687 HuMAP2_02341 |
| BRAP | HuMAP2_00652 HuMAP2_00687 HuMAP2_02341 |
| RIF1 | HuMAP2_00652 HuMAP2_06738 |
| CUL2 | HuMAP2_00567 HuMAP2_00652 HuMAP2_02018 HuMAP2_02341 |