hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00669
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| TRMT5 | tRNA (guanine(37)-N1)-methyltransferase (EC 2.1.1.228) (M1G-methyltransferase) (tRNA [GM37] methyltransferase) (tRNA methyltransferase 5 homolog) | UniProt NCBI |
| DOLPP1 | Dolichyldiphosphatase 1 (EC 3.6.1.43) (Dolichyl pyrophosphate phosphatase 1) | UniProt NCBI |
| SELENBP1 | Methanethiol oxidase (MTO) (EC 1.8.3.4) (56 kDa selenium-binding protein) (SBP56) (SP56) (Selenium-binding protein 1) | UniProt NCBI |
| MMACHC | Methylmalonic aciduria and homocystinuria type C protein (EC 1.16.1.-) (CblC) (Cyanocobalamin reductase (cyanide-eliminating)) | UniProt NCBI |
| OFCC1 | NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6540 | 0.0499140284799 | 0.25 | SELENBP1 | GPX1-SBP1 complex |
| REAC:R-HSA-3359474 | 0.0499190562503 | 0.25 | MMACHC | Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| SELENBP1 | MMACHC | 0.698 | 0.72 | bioplex (SELENBP1) bioplex_WMM |
| SELENBP1 | DOLPP1 | 0.133 | 0.406 | bioplex (DOLPP1) bioplex_WMM |
| SELENBP1 | OFCC1 | 0.054 | 0.299 | bioplex (OFCC1) bioplex_WMM |
| SELENBP1 | TRMT5 | 0.051 | 0.299 | bioplex (SELENBP1) bioplex_WMM |
| MMACHC | TRMT5 | 0.008 | 0.087 | bioplex_WMM WMM_only |
| DOLPP1 | TRMT5 | 0.007 | 0.005 | youn_WMM WMM_only |
| MMACHC | DOLPP1 | 0.007 | 0.002 | youn_WMM WMM_only |
Images
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Complex HuMAP2_00669 has an average edge precision of 0.26 which is ranked 5234 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| TRMT5 | HuMAP2_00669 HuMAP2_03771 HuMAP2_06898 HuMAP2_07011 |
| DOLPP1 | HuMAP2_00669 HuMAP2_00939 HuMAP2_02772 HuMAP2_04691 |
| SELENBP1 | HuMAP2_00210 HuMAP2_00669 HuMAP2_03445 HuMAP2_04415 HuMAP2_06581 |
| MMACHC | HuMAP2_00210 HuMAP2_00422 HuMAP2_00669 HuMAP2_06536 |
| OFCC1 | HuMAP2_00669 |