hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00677
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RAP1A | Ras-related protein Rap-1A (C21KG) (G-22K) (GTP-binding protein smg p21A) (Ras-related protein Krev-1) | UniProt NCBI |
| ANKRD13C | Ankyrin repeat domain-containing protein 13C | UniProt NCBI |
| CPLX2 | Complexin-2 (Complexin II) (CPX II) (Synaphin-1) | UniProt NCBI |
| CPLX1 | Complexin-1 (Complexin I) (CPX I) (Synaphin-2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP2267 | 0.00173204740358 | 0.5 | CPLX2 CPLX1 | Synaptic Vesicle Pathway |
| GO:0070554 | 0.00270494046827 | 0.5 | CPLX2 CPLX1 | synaptobrevin 2-SNAP-25-syntaxin-3-complexin complex |
| GO:0046928 | 0.00386509246613 | 0.75 | CPLX2 CPLX1 RAP1A | regulation of neurotransmitter secretion |
| KEGG:04721 | 0.00440435122993 | 0.5 | CPLX2 CPLX1 | Synaptic vesicle cycle |
| GO:0016079 | 0.00848863295691 | 0.75 | CPLX2 CPLX1 RAP1A | synaptic vesicle exocytosis |
| GO:0051588 | 0.0150889595431 | 0.75 | CPLX2 CPLX1 RAP1A | regulation of neurotransmitter transport |
| HP:0100276 | 0.0224167415402 | 0.5 | RAP1A CPLX1 | Skin pit |
| HP:0000384 | 0.0277254502169 | 0.5 | RAP1A CPLX1 | Preauricular skin tag |
| GO:0007269 | 0.0469269676219 | 0.75 | CPLX2 CPLX1 RAP1A | neurotransmitter secretion |
| GO:0099643 | 0.0469269676219 | 0.75 | CPLX2 CPLX1 RAP1A | signal release from synapse |
| HP:0010609 | 0.0470133620262 | 0.5 | RAP1A CPLX1 | Skin tags |
| CORUM:2256 | 0.0499140284799 | 0.25 | RAP1A | RIAM-Rap1-GTP complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CPLX2 | 55747 | 0.068 | 0.35 | bioplex (CPLX2) bioplex_WMM |
| CPLX2 | CPLX1 | 0.058 | 0.325 | bioplex (CPLX1,CPLX2) bioplex_WMM |
| ANKRD13C | CPLX2 | 0.034 | 0.263 | bioplex (CPLX2) bioplex_WMM |
| CPLX2 | RAP1A | 0.021 | 0.187 | bioplex (CPLX2) bioplex_WMM |
| CPLX1 | 55747 | 0.008 | 0.06 | bioplex_WMM WMM_only |
| ANKRD13C | CPLX1 | 0.008 | 0.04 | bioplex_WMM WMM_only |
| RAP1A | CPLX1 | 0.008 | 0.026 | bioplex_WMM WMM_only |
| ANKRD13C | 55747 | 0.008 | 0.011 | bioplex_WMM WMM_only |
| RAP1A | 55747 | 0.007 | 0.004 | bioplex_WMM WMM_only |
| ANKRD13C | RAP1A | 0.007 | 0.003 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_00677 has an average edge precision of 0.127 which is ranked 6841 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RAP1A | HuMAP2_00677 HuMAP2_03409 HuMAP2_03541 HuMAP2_04035 HuMAP2_04043 |
| ANKRD13C | HuMAP2_00271 HuMAP2_00677 HuMAP2_02689 HuMAP2_03720 HuMAP2_05763 |
| CPLX2 | HuMAP2_00677 HuMAP2_03720 HuMAP2_05750 |
| CPLX1 | HuMAP2_00677 HuMAP2_03720 HuMAP2_05750 |