hu.MAP 2.0: Complex View

Human Protein Complex Map

Complex: HuMAP2_00692

Confidence: Medium

Genename	Protein Name	Links
CTPS1	CTP synthase 1 (EC 6.3.4.2) (CTP synthetase 1) (UTP--ammonia ligase 1)	UniProt NCBI
TIGD3	Tigger transposable element-derived protein 3	UniProt NCBI
CTPS2	CTP synthase 2 (EC 6.3.4.2) (CTP synthetase 2) (UTP--ammonia ligase 2)	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
KEGG:00240	0.000547422499549	0.666666666667	CTPS2 CTPS1	Pyrimidine metabolism
GO:0003883	0.00135247023414	0.666666666667	CTPS2 CTPS1	CTP synthase activity
GO:0006241	0.00135247023414	0.666666666667	CTPS2 CTPS1	CTP biosynthetic process
GO:0046036	0.00135247023414	0.666666666667	CTPS2 CTPS1	CTP metabolic process
REAC:R-HSA-499943	0.00234745427481	0.666666666667	CTPS2 CTPS1	Interconversion of nucleotide di- and triphosphates
WP:WP4022	0.00294510433123	0.666666666667	CTPS2 CTPS1	Pyrimidine metabolism
GO:0097268	0.00405722906526	0.666666666667	CTPS2 CTPS1	cytoophidium
GO:0009209	0.00405722906526	0.666666666667	CTPS2 CTPS1	pyrimidine ribonucleoside triphosphate biosynthetic process
GO:0009148	0.00811409485621	0.666666666667	CTPS2 CTPS1	pyrimidine nucleoside triphosphate biosynthetic process
GO:0009208	0.00811409485621	0.666666666667	CTPS2 CTPS1	pyrimidine ribonucleoside triphosphate metabolic process
GO:0019856	0.0135228859698	0.666666666667	CTPS2 CTPS1	pyrimidine nucleobase biosynthetic process
REAC:R-HSA-15869	0.0243796532655	0.666666666667	CTPS2 CTPS1	Metabolism of nucleotides
GO:0009147	0.0283955176165	0.666666666667	CTPS2 CTPS1	pyrimidine nucleoside triphosphate metabolic process
GO:0009220	0.0283955176165	0.666666666667	CTPS2 CTPS1	pyrimidine ribonucleotide biosynthetic process
GO:0006206	0.0486736709081	0.666666666667	CTPS2 CTPS1	pyrimidine nucleobase metabolic process
GO:0009218	0.0486736709081	0.666666666667	CTPS2 CTPS1	pyrimidine ribonucleotide metabolic process

Protein 1	Protein 2	Score	Precision	Evidence
TIGD3	CTPS2	0.13	0.401	bioplex (TIGD3) bioplex_WMM
CTPS1	CTPS2	0.069	0.348	hein_WMM bioplex (CTPS2) bioplex_WMM gupta_WMM
CTPS1	TIGD3	0.022	0.207	bioplex (TIGD3) bioplex_WMM

Click to enlarge

ComplexPrecisionDistribution

Complex HuMAP2_00692 has an average edge precision of 0.319 which is ranked 4360 out of all 6965 complexes.

Related Complexes

Genename	Complexes
CTPS1	HuMAP2_00692 HuMAP2_02731 HuMAP2_05170 HuMAP2_05725
TIGD3	HuMAP2_00692 HuMAP2_02731 HuMAP2_05170 HuMAP2_05725
CTPS2	HuMAP2_00692 HuMAP2_02731 HuMAP2_05170 HuMAP2_05725