hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00701
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| BMT2 | S-adenosylmethionine sensor upstream of mTORC1 (Probable methyltransferase BMT2 homolog) (EC 2.1.1.-) | UniProt NCBI |
| DEPDC5 | GATOR complex protein DEPDC5 (DEP domain-containing protein 5) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:1990130 | 0.00676235117068 | 1.0 | DEPDC5 BMT2 | GATOR1 complex |
| GO:1904262 | 0.0410249304355 | 1.0 | DEPDC5 BMT2 | negative regulation of TORC1 signaling |
| HP:0032047 | 0.0497341708567 | 0.5 | DEPDC5 | Focal cortical dysplasia type I |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DEPDC5 | BMT2 | 0.533 | 0.638 | bioplex (BMT2) bioplex_WMM |
Images
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Complex HuMAP2_00701 has an average edge precision of 0.638 which is ranked 1726 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| BMT2 | HuMAP2_00503 HuMAP2_00701 HuMAP2_01040 HuMAP2_01293 |
| DEPDC5 | HuMAP2_00503 HuMAP2_00701 HuMAP2_01040 HuMAP2_01293 HuMAP2_04382 |