hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00710
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| HIF1A | Hypoxia-inducible factor 1-alpha (HIF-1-alpha) (HIF1-alpha) (ARNT-interacting protein) (Basic-helix-loop-helix-PAS protein MOP1) (Class E basic helix-loop-helix protein 78) (bHLHe78) (Member of PAS protein 1) (PAS domain-containing protein 8) | UniProt NCBI |
| MYH6 | Myosin-6 (Myosin heavy chain 6) (Myosin heavy chain, cardiac muscle alpha isoform) (MyHC-alpha) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04919 | 0.00092323965929 | 1.0 | MYH6 HIF1A | Thyroid hormone signaling pathway |
| WP:WP3672 | 0.0277405430531 | 0.5 | HIF1A | LncRNA-mediated mechanisms of therapeutic resistance |
| WP:WP3593 | 0.038834152205 | 0.5 | HIF1A | MicroRNA for Targeting Cancer Growth and Vascularization in Glioblastoma |
| WP:WP2456 | 0.0443803979089 | 0.5 | HIF1A | HIF1A and PPARG regulation of glycolysis |
| CORUM:5382 | 0.0499173803268 | 0.5 | HIF1A | ARNT-HIF1A complex |
| CORUM:7273 | 0.0499173803268 | 0.5 | HIF1A | ARNTL-HIF1A complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| HIF1A | MYH6 | 0.996 | 0.928 | bioplex (HIF1A) bioplex_WMM |
Images
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Complex HuMAP2_00710 has an average edge precision of 0.928 which is ranked 439 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| HIF1A | HuMAP2_00710 HuMAP2_03104 HuMAP2_04482 HuMAP2_04733 HuMAP2_06061 |
| MYH6 | HuMAP2_00710 HuMAP2_01870 HuMAP2_02652 HuMAP2_03104 HuMAP2_04204 HuMAP2_06061 HuMAP2_06387 |