hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00711
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ATP1A4 | Sodium/potassium-transporting ATPase subunit alpha-4 (Na(+)/K(+) ATPase alpha-4 subunit) (EC 7.2.2.13) (Sodium pump subunit alpha-4) | UniProt NCBI |
| CHRM3 | Muscarinic acetylcholine receptor M3 | UniProt NCBI |
| ATP1B4 | Protein ATP1B4 (X,K-ATPase subunit beta-m) (X/potassium-transporting ATPase subunit beta-m) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04971 | 1.08230481824e-06 | 1.0 | ATP1A4 CHRM3 ATP1B4 | Gastric acid secretion |
| KEGG:04911 | 1.79351651458e-06 | 1.0 | ATP1A4 CHRM3 ATP1B4 | Insulin secretion |
| KEGG:04970 | 1.94941171262e-06 | 1.0 | ATP1A4 CHRM3 ATP1B4 | Salivary secretion |
| KEGG:04972 | 2.56577513453e-06 | 1.0 | ATP1A4 CHRM3 ATP1B4 | Pancreatic secretion |
| KEGG:04964 | 8.50206218982e-05 | 0.666666666667 | ATP1B4 ATP1A4 | Proximal tubule bicarbonate reclamation |
| KEGG:04960 | 0.000207974238369 | 0.666666666667 | ATP1B4 ATP1A4 | Aldosterone-regulated sodium reabsorption |
| KEGG:04973 | 0.000348719274028 | 0.666666666667 | ATP1B4 ATP1A4 | Carbohydrate digestion and absorption |
| KEGG:04978 | 0.000462599152438 | 0.666666666667 | ATP1B4 ATP1A4 | Mineral absorption |
| KEGG:04961 | 0.000547422499549 | 0.666666666667 | ATP1B4 ATP1A4 | Endocrine and other factor-regulated calcium reabsorption |
| KEGG:04976 | 0.00068800303931 | 0.666666666667 | ATP1B4 ATP1A4 | Bile secretion |
| KEGG:04918 | 0.00101716035293 | 0.666666666667 | ATP1B4 ATP1A4 | Thyroid hormone synthesis |
| KEGG:04974 | 0.0012386886924 | 0.666666666667 | ATP1B4 ATP1A4 | Protein digestion and absorption |
| KEGG:04260 | 0.00127210962765 | 0.666666666667 | ATP1B4 ATP1A4 | Cardiac muscle contraction |
| KEGG:04925 | 0.0017077231529 | 0.666666666667 | ATP1B4 ATP1A4 | Aldosterone synthesis and secretion |
| KEGG:04919 | 0.00281983571039 | 0.666666666667 | ATP1B4 ATP1A4 | Thyroid hormone signaling pathway |
| KEGG:04261 | 0.00367632825889 | 0.666666666667 | ATP1B4 ATP1A4 | Adrenergic signaling in cardiomyocytes |
| KEGG:04022 | 0.00439265454468 | 0.666666666667 | ATP1B4 ATP1A4 | cGMP-PKG signaling pathway |
| KEGG:04024 | 0.0063848075241 | 0.666666666667 | ATP1B4 ATP1A4 | cAMP signaling pathway |
| WP:WP536 | 0.00681250105954 | 0.666666666667 | CHRM3 ATP1A4 | Calcium Regulation in the Cardiac Cell |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CHRM3 | ATP1A4 | 0.366 | 0.543 | bioplex (CHRM3) bioplex_WMM |
| ATP1B4 | ATP1A4 | 0.349 | 0.536 | bioplex (ATP1B4) bioplex_WMM |
Images
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Complex HuMAP2_00711 has an average edge precision of 0.54 which is ranked 2276 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ATP1A4 | HuMAP2_00711 HuMAP2_02155 HuMAP2_02677 HuMAP2_03681 HuMAP2_04770 HuMAP2_06535 HuMAP2_06635 |
| CHRM3 | HuMAP2_00711 HuMAP2_02155 HuMAP2_04472 HuMAP2_04770 |
| ATP1B4 | HuMAP2_00711 HuMAP2_02155 HuMAP2_04770 HuMAP2_06535 |