hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00734
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| UGP2 | UTP--glucose-1-phosphate uridylyltransferase (EC 2.7.7.9) (UDP-glucose pyrophosphorylase) (UDPGP) (UGPase) | UniProt NCBI |
| PFKP | ATP-dependent 6-phosphofructokinase, platelet type (ATP-PFK) (PFK-P) (EC 2.7.1.11) (6-phosphofructokinase type C) (Phosphofructo-1-kinase isozyme C) (PFK-C) (Phosphohexokinase) | UniProt NCBI |
| PFKL | ATP-dependent 6-phosphofructokinase, liver type (ATP-PFK) (PFK-L) (EC 2.7.1.11) (6-phosphofructokinase type B) (Phosphofructo-1-kinase isozyme B) (PFK-B) (Phosphohexokinase) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00052 | 8.79617002873e-08 | 1.0 | PFKP UGP2 PFKL | Galactose metabolism |
| KEGG:00030 | 0.000181602388379 | 0.666666666667 | PFKP PFKL | Pentose phosphate pathway |
| KEGG:00051 | 0.000236130222292 | 0.666666666667 | PFKP PFKL | Fructose and mannose metabolism |
| KEGG:00010 | 0.00087223886567 | 0.666666666667 | PFKP PFKL | Glycolysis / Gluconeogenesis |
| WP:WP534 | 0.000905695914221 | 0.666666666667 | PFKP PFKL | Glycolysis and Gluconeogenesis |
| KEGG:05230 | 0.000987288198645 | 0.666666666667 | PFKP PFKL | Central carbon metabolism in cancer |
| KEGG:01230 | 0.00110943942397 | 0.666666666667 | PFKP PFKL | Biosynthesis of amino acids |
| KEGG:03018 | 0.00127210962765 | 0.666666666667 | PFKP PFKL | RNA degradation |
| REAC:R-HSA-71387 | 0.00133225455863 | 1.0 | PFKP UGP2 PFKL | Metabolism of carbohydrates |
| KEGG:04922 | 0.00203354700377 | 0.666666666667 | PFKP PFKL | Glucagon signaling pathway |
| KEGG:04066 | 0.00220707183162 | 0.666666666667 | PFKP PFKL | HIF-1 signaling pathway |
| KEGG:04152 | 0.00277005173367 | 0.666666666667 | PFKP PFKL | AMPK signaling pathway |
| KEGG:01200 | 0.00287006078872 | 0.666666666667 | PFKP PFKL | Carbon metabolism |
| WP:WP4018 | 0.00302048413579 | 0.666666666667 | PFKP PFKL | Pathways in clear cell renal cell carcinoma |
| GO:0005945 | 0.00405722906526 | 0.666666666667 | PFKP PFKL | 6-phosphofructokinase complex |
| GO:0003872 | 0.00405722906526 | 0.666666666667 | PFKP PFKL | 6-phosphofructokinase activity |
| GO:0070095 | 0.00811409485621 | 0.666666666667 | PFKP PFKL | fructose-6-phosphate binding |
| KEGG:01100 | 0.0105851300972 | 1.0 | PFKP UGP2 PFKL | Metabolic pathways |
| REAC:R-HSA-70171 | 0.0143204798819 | 0.666666666667 | PFKP PFKL | Glycolysis |
| REAC:R-HSA-70326 | 0.022155781492 | 0.666666666667 | PFKP PFKL | Glucose metabolism |
| GO:0008443 | 0.0283955176165 | 0.666666666667 | PFKP PFKL | phosphofructokinase activity |
| GO:0016208 | 0.0486736709081 | 0.666666666667 | PFKP PFKL | AMP binding |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PFKP | PFKL | 0.47 | 0.605 | hein_WMM bioplex (PFKL,PFKP) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM treiber_WMM |
| UGP2 | PFKP | 0.087 | 0.353 | fraction treiber_WMM |
| UGP2 | PFKL | 0.046 | 0.293 | fraction treiber_WMM |
Images
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Complex HuMAP2_00734 has an average edge precision of 0.417 which is ranked 3133 out of all 6965 complexes.
Related Complexes