hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_00749
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PDHA2 | Pyruvate dehydrogenase E1 component subunit alpha, testis-specific form, mitochondrial (EC 1.2.4.1) (PDHE1-A type II) | UniProt NCBI |
| PDK3 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial (EC 2.7.11.2) (Pyruvate dehydrogenase kinase isoform 3) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-204174 | 0.000201110815485 | 1.0 | PDHA2 PDK3 | Regulation of pyruvate dehydrogenase (PDH) complex |
| REAC:R-HSA-70268 | 0.000680424925724 | 1.0 | PDHA2 PDK3 | Pyruvate metabolism |
| REAC:R-HSA-5362517 | 0.00130722030065 | 1.0 | PDHA2 PDK3 | Signaling by Retinoic Acid |
| REAC:R-HSA-71406 | 0.00222227451111 | 1.0 | PDHA2 PDK3 | Pyruvate metabolism and Citric Acid (TCA) cycle |
| REAC:R-HSA-1428517 | 0.0226752444459 | 1.0 | PDHA2 PDK3 | The citric acid (TCA) cycle and respiratory electron transport |
| WP:WP528 | 0.038834152205 | 0.5 | PDHA2 | Acetylcholine Synthesis |
| REAC:R-HSA-9006931 | 0.0496844269656 | 1.0 | PDHA2 PDK3 | Signaling by Nuclear Receptors |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PDHA2 | PDK3 | 1.0 | 0.949 | bioplex (PDK3) bioplex_WMM |
Images
Click to enlarge
Complex HuMAP2_00749 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PDHA2 | HuMAP2_00749 HuMAP2_01188 HuMAP2_02405 HuMAP2_02908 HuMAP2_06120 HuMAP2_06177 |
| PDK3 | HuMAP2_00749 HuMAP2_01188 HuMAP2_02405 HuMAP2_02908 HuMAP2_06086 |