hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00753
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| FCGR3A | Low affinity immunoglobulin gamma Fc region receptor III-A (CD16a antigen) (Fc-gamma RIII-alpha) (Fc-gamma RIII) (Fc-gamma RIIIa) (FcRIII) (FcRIIIa) (FcR-10) (IgG Fc receptor III-2) (CD antigen CD16a) | UniProt NCBI |
| PLAUR | Urokinase plasminogen activator surface receptor (U-PAR) (uPAR) (Monocyte activation antigen Mo3) (CD antigen CD87) | UniProt NCBI |
| VWA8 | von Willebrand factor A domain-containing protein 8 (PEX7-binding protein 2) (P7BP2) | UniProt NCBI |
| RIOK3 | Serine/threonine-protein kinase RIO3 (EC 2.7.11.1) (RIO kinase 3) (sudD homolog) | UniProt NCBI |
| MAN2A1 | Alpha-mannosidase 2 (EC 3.2.1.114) (Golgi alpha-mannosidase II) (AMan II) (Man II) (Mannosidase alpha class 2A member 1) (Mannosyl-oligosaccharide 1,3-1,6-alpha-mannosidase) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| WP:WP2806 | 0.0104424923561 | 0.4 | FCGR3A PLAUR | Human Complement System |
| CORUM:7108 | 0.0499494897235 | 0.2 | PLAUR | IGF2R-PLAUR complex |
| CORUM:7112 | 0.0499494897235 | 0.2 | PLAUR | PLAUR-PLAU complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| FCGR3A | RIOK3 | 0.276 | 0.487 | bioplex (FCGR3A) bioplex_WMM |
| RIOK3 | PLAUR | 0.064 | 0.347 | bioplex (PLAUR) bioplex_WMM |
| PLAUR | MAN2A1 | 0.043 | 0.273 | bioplex (PLAUR) bioplex_WMM |
| VWA8 | MAN2A1 | 0.04 | 0.269 | bioplex_WMM fraction |
| RIOK3 | MAN2A1 | 0.007 | 0.003 | bioplex_WMM WMM_only |
| VWA8 | PLAUR | 0.003 | 0.011 | bioplex (PLAUR) |
Images
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Complex HuMAP2_00753 has an average edge precision of 0.232 which is ranked 5665 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| FCGR3A | HuMAP2_00753 HuMAP2_02004 HuMAP2_05604 HuMAP2_05829 |
| PLAUR | HuMAP2_00753 HuMAP2_02004 HuMAP2_05604 HuMAP2_05829 |
| VWA8 | HuMAP2_00753 HuMAP2_05381 HuMAP2_05563 HuMAP2_05613 HuMAP2_05909 |
| RIOK3 | HuMAP2_00753 HuMAP2_02004 HuMAP2_05604 HuMAP2_05829 |
| MAN2A1 | HuMAP2_00753 HuMAP2_01074 HuMAP2_02004 HuMAP2_05613 |