hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00771
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SNTB2 | Beta-2-syntrophin (59 kDa dystrophin-associated protein A1 basic component 2) (Syntrophin-3) (SNT3) (Syntrophin-like) (SNTL) | UniProt NCBI |
| UTRN | Utrophin (Dystrophin-related protein 1) (DRP-1) | UniProt NCBI |
| PAPOLG | Poly(A) polymerase gamma (PAP-gamma) (EC 2.7.7.19) (Neo-poly(A) polymerase) (Neo-PAP) (Polynucleotide adenylyltransferase gamma) (SRP RNA 3'-adenylating enzyme) (Signal recognition particle RNA-adenylating enzyme) (SRP RNA-adenylating enzyme) | UniProt NCBI |
| DTNA | Dystrobrevin alpha (DTN-A) (Alpha-dystrobrevin) (Dystrophin-related protein 3) | UniProt NCBI |
| SNTA1 | Alpha-1-syntrophin (59 kDa dystrophin-associated protein A1 acidic component 1) (Pro-TGF-alpha cytoplasmic domain-interacting protein 1) (TACIP1) (Syntrophin-1) | UniProt NCBI |
| SNTB1 | Beta-1-syntrophin (59 kDa dystrophin-associated protein A1 basic component 1) (DAPA1B) (BSYN2) (Syntrophin-2) (Tax interaction protein 43) (TIP-43) | UniProt NCBI |
| LPAR6 | Lysophosphatidic acid receptor 6 (LPA receptor 6) (LPA-6) (Oleoyl-L-alpha-lysophosphatidic acid receptor) (P2Y purinoceptor 5) (P2Y5) (Purinergic receptor 5) (RB intron encoded G-protein coupled receptor) | UniProt NCBI |
| LONRF3 | LON peptidase N-terminal domain and RING finger protein 3 (RING finger protein 127) | UniProt NCBI |
| DTNB | Dystrobrevin beta (DTN-B) (Beta-dystrobrevin) | UniProt NCBI |
| SNTG2 | Gamma-2-syntrophin (G2SYN) (Syntrophin-5) (SYN5) | UniProt NCBI |
| DMD | Dystrophin | UniProt NCBI |
| CTNNAL1 | Alpha-catulin (Alpha-catenin-related protein) (ACRP) (Catenin alpha-like protein 1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0016010 | 1.29432526962e-08 | 0.416666666667 | SNTB2 SNTG2 DMD SNTB1 SNTA1 | dystrophin-associated glycoprotein complex |
| GO:0090665 | 1.29432526962e-08 | 0.416666666667 | SNTB2 SNTG2 DMD SNTB1 SNTA1 | glycoprotein complex |
| CORUM:7341 | 3.69160609814e-05 | 0.166666666667 | DTNA CTNNAL1 | CTNNAL1-DNTA complex |
| GO:0016013 | 7.98841194917e-05 | 0.25 | SNTA1 DMD SNTG2 | syntrophin complex |
| GO:0006936 | 0.0228464651068 | 0.416666666667 | DTNA UTRN DMD SNTB1 SNTA1 | muscle contraction |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DMD | CTNNAL1 | 0.939 | 0.85 | bioplex (DMD) bioplex_WMM fraction |
| DMD | SNTB1 | 0.904 | 0.827 | bioplex (DMD) bioplex_WMM |
| DMD | SNTG2 | 0.867 | 0.801 | bioplex (SNTG2) bioplex_WMM |
| SNTB1 | SNTG2 | 0.842 | 0.786 | bioplex (SNTG2) bioplex_WMM |
| SNTG2 | UTRN | 0.841 | 0.785 | bioplex (SNTG2) bioplex_WMM |
| DMD | DTNB | 0.656 | 0.694 | bioplex (DMD) bioplex_WMM |
| DMD | DTNA | 0.649 | 0.687 | bioplex (DMD) bioplex_WMM boldt_WMM |
| DMD | SNTA1 | 0.578 | 0.66 | bioplex (DMD) bioplex_WMM |
| DTNA | SNTG2 | 0.538 | 0.642 | bioplex (SNTG2) bioplex_WMM |
| DTNB | SNTG2 | 0.445 | 0.589 | bioplex (SNTG2) bioplex_WMM |
| SNTA1 | SNTG2 | 0.344 | 0.534 | bioplex (SNTG2) bioplex_WMM |
| SNTB2 | SNTG2 | 0.268 | 0.482 | bioplex (SNTG2) bioplex_WMM |
| DMD | SNTB2 | 0.242 | 0.468 | bioplex (DMD) bioplex_WMM |
| CTNNAL1 | SNTG2 | 0.23 | 0.468 | bioplex (SNTG2) bioplex_WMM |
| DMD | LPAR6 | 0.188 | 0.438 | bioplex (LPAR6) bioplex_WMM |
| DMD | LONRF3 | 0.084 | 0.347 | bioplex (DMD) bioplex_WMM |
| CTNNAL1 | PAPOLG | 0.035 | 0.262 | fraction |
| SNTB1 | SNTA1 | 0.015 | 0.144 | bioplex_WMM WMM_only |
| SNTB2 | DTNB | 0.013 | 0.144 | bioplex_WMM gupta_WMM WMM_only |
| SNTB2 | SNTA1 | 0.013 | 0.154 | bioplex_WMM WMM_only |
| SNTB2 | UTRN | 0.013 | 0.149 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| SNTB1 | SNTB2 | 0.012 | 0.147 | bioplex_WMM gupta_WMM WMM_only |
| DTNB | UTRN | 0.012 | 0.149 | bioplex_WMM gupta_WMM WMM_only |
| DTNA | DTNB | 0.012 | 0.15 | bioplex_WMM WMM_only |
| DTNA | SNTB2 | 0.011 | 0.141 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| DTNA | SNTA1 | 0.011 | 0.142 | bioplex_WMM WMM_only |
| SNTB1 | UTRN | 0.01 | 0.137 | bioplex_WMM gupta_WMM WMM_only |
| SNTA1 | UTRN | 0.01 | 0.13 | bioplex_WMM WMM_only |
| SNTB1 | DTNA | 0.01 | 0.118 | bioplex_WMM WMM_only |
| DMD | UTRN | 0.009 | 0.114 | bioplex (DMD) bioplex_WMM boldt_WMM |
| SNTB1 | CTNNAL1 | 0.009 | 0.106 | bioplex_WMM WMM_only |
| CTNNAL1 | SNTA1 | 0.009 | 0.107 | bioplex_WMM WMM_only |
| CTNNAL1 | DTNB | 0.009 | 0.093 | bioplex_WMM gupta_WMM WMM_only |
| CTNNAL1 | UTRN | 0.009 | 0.095 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| DTNB | SNTA1 | 0.009 | 0.096 | bioplex_WMM WMM_only |
| SNTB1 | DTNB | 0.009 | 0.097 | bioplex_WMM WMM_only |
| CTNNAL1 | SNTB2 | 0.008 | 0.095 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| CTNNAL1 | DTNA | 0.008 | 0.096 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| DTNA | UTRN | 0.008 | 0.086 | bioplex_WMM youn_WMM gupta_WMM WMM_only boldt_WMM |
| SNTB1 | LONRF3 | 0.008 | 0.041 | bioplex_WMM WMM_only |
| CTNNAL1 | LONRF3 | 0.008 | 0.041 | bioplex_WMM WMM_only |
| SNTA1 | LONRF3 | 0.008 | 0.04 | bioplex_WMM WMM_only |
| DTNB | LONRF3 | 0.008 | 0.024 | bioplex_WMM WMM_only |
| LONRF3 | UTRN | 0.008 | 0.016 | bioplex_WMM WMM_only |
| DTNA | LONRF3 | 0.008 | 0.011 | bioplex_WMM WMM_only |
| SNTB2 | LONRF3 | 0.008 | 0.011 | bioplex_WMM WMM_only |
| UTRN | PAPOLG | 0.005 | 0.008 | fraction |
Images
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Complex HuMAP2_00771 has an average edge precision of 0.281 which is ranked 4872 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SNTB2 | HuMAP2_00771 HuMAP2_05558 HuMAP2_06572 |
| UTRN | HuMAP2_00771 HuMAP2_00783 HuMAP2_05930 |
| PAPOLG | HuMAP2_00771 HuMAP2_03044 HuMAP2_05845 |
| DTNA | HuMAP2_00771 HuMAP2_06572 |
| SNTA1 | HuMAP2_00771 HuMAP2_06572 |
| SNTB1 | HuMAP2_00439 HuMAP2_00771 HuMAP2_06572 |
| LPAR6 | HuMAP2_00771 HuMAP2_01932 HuMAP2_02909 |
| LONRF3 | HuMAP2_00771 |
| DTNB | HuMAP2_00771 HuMAP2_05097 HuMAP2_06572 |
| SNTG2 | HuMAP2_00771 HuMAP2_05930 HuMAP2_06572 |
| DMD | HuMAP2_00439 HuMAP2_00771 HuMAP2_06572 |
| CTNNAL1 | HuMAP2_00439 HuMAP2_00771 HuMAP2_03044 HuMAP2_05845 HuMAP2_06572 |