hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00772
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ATP6V1B2 | V-type proton ATPase subunit B, brain isoform (V-ATPase subunit B 2) (Endomembrane proton pump 58 kDa subunit) (HO57) (Vacuolar proton pump subunit B 2) | UniProt NCBI |
| ATP6V0D1 | V-type proton ATPase subunit d 1 (V-ATPase subunit d 1) (32 kDa accessory protein) (V-ATPase 40 kDa accessory protein) (V-ATPase AC39 subunit) (p39) (Vacuolar proton pump subunit d 1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04966 | 4.37692632407e-05 | 1.0 | ATP6V1B2 ATP6V0D1 | Collecting duct acid secretion |
| CORUM:6888 | 0.000152509035076 | 1.0 | ATP6V1B2 ATP6V0D1 | v-ATPase-Ragulator-AXIN/LKB1-AMPK complex |
| KEGG:05110 | 0.000164572429785 | 1.0 | ATP6V1B2 ATP6V0D1 | Vibrio cholerae infection |
| KEGG:05323 | 0.000224682217969 | 1.0 | ATP6V1B2 ATP6V0D1 | Rheumatoid arthritis |
| KEGG:05120 | 0.000266992505768 | 1.0 | ATP6V1B2 ATP6V0D1 | Epithelial cell signaling in Helicobacter pylori infection |
| KEGG:04721 | 0.000322579470084 | 1.0 | ATP6V1B2 ATP6V0D1 | Synaptic vesicle cycle |
| REAC:R-HSA-77387 | 0.000462554875615 | 1.0 | ATP6V1B2 ATP6V0D1 | Insulin receptor recycling |
| REAC:R-HSA-917977 | 0.000680424925724 | 1.0 | ATP6V1B2 ATP6V0D1 | Transferrin endocytosis and recycling |
| REAC:R-HSA-1222556 | 0.000831258037338 | 1.0 | ATP6V1B2 ATP6V0D1 | ROS and RNS production in phagocytes |
| KEGG:00190 | 0.00100713074717 | 1.0 | ATP6V1B2 ATP6V0D1 | Oxidative phosphorylation |
| KEGG:04145 | 0.00131964328671 | 1.0 | ATP6V1B2 ATP6V0D1 | Phagosome |
| REAC:R-HSA-917937 | 0.00239824647466 | 1.0 | ATP6V1B2 ATP6V0D1 | Iron uptake and transport |
| REAC:R-HSA-74752 | 0.00286750504412 | 1.0 | ATP6V1B2 ATP6V0D1 | Signaling by Insulin receptor |
| KEGG:05165 | 0.00707836525128 | 1.0 | ATP6V1B2 ATP6V0D1 | Human papillomavirus infection |
| REAC:R-HSA-983712 | 0.0213177464414 | 1.0 | ATP6V1B2 ATP6V0D1 | Ion channel transport |
| GO:0046961 | 0.0473364581948 | 1.0 | ATP6V1B2 ATP6V0D1 | proton-transporting ATPase activity, rotational mechanism |
| HP:0005322 | 0.0497341708567 | 0.5 | ATP6V1B2 | Prominent nasal septum |
| HP:0007529 | 0.0497341708567 | 0.5 | ATP6V1B2 | Hidrotic ectodermal dysplasia |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ATP6V0D1 | ATP6V1B2 | 0.924 | 0.844 | hein_WMM bioplex (ATP6V0D1) bioplex_WMM Guru fraction |
Images
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Complex HuMAP2_00772 has an average edge precision of 0.844 which is ranked 790 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ATP6V1B2 | HuMAP2_00772 HuMAP2_01065 HuMAP2_01514 HuMAP2_06925 |
| ATP6V0D1 | HuMAP2_00515 HuMAP2_00772 HuMAP2_01018 HuMAP2_01065 HuMAP2_01270 HuMAP2_02034 HuMAP2_02651 HuMAP2_04677 HuMAP2_06925 |