hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00775
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PCLAF | PCNA-associated factor (Hepatitis C virus NS5A-transactivated protein 9) (HCV NS5A-transactivated protein 9) (Overexpressed in anaplastic thyroid carcinoma 1) (OEATC-1) (PCNA-associated factor of 15 kDa) (PAF15) (p15PAF) (PCNA-clamp-associated factor) | UniProt NCBI |
| UGT3A1 | UDP-glucuronosyltransferase 3A1 (UDPGT 3A1) (EC 2.4.1.17) | UniProt NCBI |
| PCNA | Proliferating cell nuclear antigen (PCNA) (Cyclin) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1039 | 3.35600554376e-06 | 0.666666666667 | PCLAF PCNA | PCNA-PAF complex |
| REAC:R-HSA-5656169 | 0.00310931782116 | 0.666666666667 | PCLAF PCNA | Termination of translesion DNA synthesis |
| REAC:R-HSA-110313 | 0.0046992786316 | 0.666666666667 | PCLAF PCNA | Translesion synthesis by Y family DNA polymerases bypasses lesions on DNA template |
| REAC:R-HSA-73893 | 0.00722314394396 | 0.666666666667 | PCLAF PCNA | DNA Damage Bypass |
| MIRNA:hsa-miR-3156-5p | 0.0149526346792 | 0.666666666667 | PCLAF UGT3A1 | hsa-miR-3156-5p |
| CORUM:2231 | 0.0249904952816 | 0.333333333333 | PCNA | PCNA homotrimer complex |
| CORUM:314 | 0.0499776345577 | 0.333333333333 | PCNA | PCNA-p21 complex |
| CORUM:1040 | 0.0499776345577 | 0.333333333333 | PCLAF | p33ING1b-PCNA complex |
| CORUM:1163 | 0.0499776345577 | 0.333333333333 | PCNA | ING1-PCNA complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PCLAF | PCNA | 0.997 | 0.933 | hein_WMM bioplex (PCNA) bioplex_WMM hein (PCNA) |
| UGT3A1 | PCNA | 0.049 | 0.295 | bioplex (UGT3A1) fraction |
Images
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Complex HuMAP2_00775 has an average edge precision of 0.614 which is ranked 1867 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PCLAF | HuMAP2_00775 HuMAP2_04364 HuMAP2_05422 HuMAP2_05853 HuMAP2_06224 |
| UGT3A1 | HuMAP2_00775 HuMAP2_02165 HuMAP2_06224 |
| PCNA | HuMAP2_00775 HuMAP2_05422 HuMAP2_06224 |