hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00783
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PAFAH1B1 | Platelet-activating factor acetylhydrolase IB subunit alpha (Lissencephaly-1 protein) (LIS-1) (PAF acetylhydrolase 45 kDa subunit) (PAF-AH 45 kDa subunit) (PAF-AH alpha) (PAFAH alpha) | UniProt NCBI |
| CCSER2 | Serine-rich coiled-coil domain-containing protein 2 (Coiled-coil serine-rich protein 2) (Protein GCAP14 homolog) | UniProt NCBI |
| NDEL1 | Nuclear distribution protein nudE-like 1 (Protein Nudel) (Mitosin-associated protein 1) | UniProt NCBI |
| ALDH9A1 | 4-trimethylaminobutyraldehyde dehydrogenase (TMABA-DH) (TMABALDH) (EC 1.2.1.47) (Aldehyde dehydrogenase E3 isozyme) (Aldehyde dehydrogenase family 9 member A1) (EC 1.2.1.3) (Gamma-aminobutyraldehyde dehydrogenase) (EC 1.2.1.19) (R-aminobutyraldehyde dehydrogenase) [Cleaved into: 4-trimethylaminobutyraldehyde dehydrogenase, N-terminally processed] | UniProt NCBI |
| DIXDC1 | Dixin (Coiled-coil protein DIX1) (Coiled-coil-DIX1) (DIX domain-containing protein 1) | UniProt NCBI |
| TRIM7 | E3 ubiquitin-protein ligase TRIM7 (EC 2.3.2.27) (Glycogenin-interacting protein) (RING finger protein 90) (Tripartite motif-containing protein 7) | UniProt NCBI |
| CCSER1 | Serine-rich coiled-coil domain-containing protein 1 (Coiled-coil serine-rich protein 1) | UniProt NCBI |
| UTRN | Utrophin (Dystrophin-related protein 1) (DRP-1) | UniProt NCBI |
| L3HYPDH | Trans-3-hydroxy-L-proline dehydratase (EC 4.2.1.77) (Trans-L-3-hydroxyproline dehydratase) | UniProt NCBI |
| ANKRD26 | Ankyrin repeat domain-containing protein 26 | UniProt NCBI |
| DISC1 | Disrupted in schizophrenia 1 protein | UniProt NCBI |
| NDE1 | Nuclear distribution protein nudE homolog 1 (NudE) | UniProt NCBI |
| SLC25A43 | Solute carrier family 25 member 43 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-141444 | 0.0149219425855 | 0.230769230769 | PAFAH1B1 NDEL1 NDE1 | Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal |
| REAC:R-HSA-141424 | 0.0149219425855 | 0.230769230769 | PAFAH1B1 NDEL1 NDE1 | Amplification of signal from the kinetochores |
| REAC:R-HSA-69618 | 0.0234069302688 | 0.230769230769 | PAFAH1B1 NDEL1 NDE1 | Mitotic Spindle Checkpoint |
| REAC:R-HSA-2500257 | 0.0329022244043 | 0.230769230769 | PAFAH1B1 NDEL1 NDE1 | Resolution of Sister Chromatid Cohesion |
| KEGG:00330 | 0.0395278906516 | 0.153846153846 | L3HYPDH ALDH9A1 | Arginine and proline metabolism |
| REAC:R-HSA-5663220 | 0.0446129277211 | 0.230769230769 | PAFAH1B1 NDEL1 NDE1 | RHO GTPases Activate Formins |
| CORUM:6061 | 0.0499905325622 | 0.0769230769231 | DISC1 | DISC1-ZNF365 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DIXDC1 | NDEL1 | 1.0 | 0.949 | hein_WMM bioplex (NDEL1) bioplex_WMM hein (NDEL1) |
| CCSER2 | NDEL1 | 1.0 | 0.949 | hein_WMM bioplex (NDEL1) bioplex_WMM youn_WMM hein (CCSER2,NDEL1) gupta_WMM |
| NDEL1 | PAFAH1B1 | 0.999 | 0.949 | hein_WMM bioplex (NDEL1) bioplex_WMM boldt (PAFAH1B1) hein (NDEL1,PAFAH1B1) gupta_WMM boldt_WMM |
| NDE1 | NDEL1 | 0.964 | 0.873 | hein_WMM bioplex (NDEL1) bioplex_WMM boldt gupta_WMM boldt_WMM |
| DISC1 | NDEL1 | 0.64 | 0.687 | bioplex (NDEL1) bioplex_WMM |
| NDEL1 | TRIM7 | 0.282 | 0.487 | bioplex (NDEL1) bioplex_WMM |
| CCSER2 | NDE1 | 0.268 | 0.483 | hein_WMM bioplex_WMM hein (CCSER2) gupta_WMM |
| NDE1 | PAFAH1B1 | 0.265 | 0.481 | hein_WMM bioplex_WMM boldt (PAFAH1B1) hein (PAFAH1B1) gupta_WMM boldt_WMM |
| NDEL1 | CCSER1 | 0.151 | 0.411 | bioplex (CCSER1,NDEL1) bioplex_WMM |
| DIXDC1 | L3HYPDH | 0.142 | 0.406 | bioplex (L3HYPDH) bioplex_WMM |
| NDEL1 | ANKRD26 | 0.043 | 0.272 | bioplex (NDEL1) bioplex_WMM youn_WMM gupta_WMM |
| PAFAH1B1 | ALDH9A1 | 0.034 | 0.261 | bioplex_WMM fraction boldt_WMM treiber_WMM |
| NDEL1 | UTRN | 0.032 | 0.245 | bioplex (NDEL1) bioplex_WMM youn_WMM gupta_WMM |
| DIXDC1 | PAFAH1B1 | 0.023 | 0.208 | hein_WMM bioplex_WMM hein (PAFAH1B1) |
| NDE1 | CCSER1 | 0.023 | 0.209 | bioplex (CCSER1) bioplex_WMM |
| NDEL1 | SLC25A43 | 0.02 | 0.187 | bioplex (SLC25A43) bioplex_WMM |
| CCSER2 | PAFAH1B1 | 0.017 | 0.171 | hein_WMM bioplex_WMM hein (CCSER2,PAFAH1B1) gupta_WMM |
| DIXDC1 | UTRN | 0.01 | 0.119 | bioplex_WMM WMM_only |
| CCSER2 | TRIM7 | 0.009 | 0.095 | bioplex_WMM WMM_only |
| DIXDC1 | CCSER2 | 0.009 | 0.095 | hein_WMM bioplex_WMM WMM_only |
| CCSER2 | CCSER1 | 0.008 | 0.091 | bioplex_WMM WMM_only |
| TRIM7 | CCSER1 | 0.008 | 0.091 | bioplex_WMM WMM_only |
| DIXDC1 | TRIM7 | 0.008 | 0.091 | bioplex_WMM WMM_only |
| TRIM7 | PAFAH1B1 | 0.008 | 0.087 | bioplex_WMM WMM_only |
| CCSER2 | UTRN | 0.008 | 0.081 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| DIXDC1 | CCSER1 | 0.008 | 0.085 | bioplex_WMM WMM_only |
| TRIM7 | ANKRD26 | 0.008 | 0.085 | bioplex_WMM WMM_only |
| UTRN | TRIM7 | 0.008 | 0.066 | bioplex_WMM WMM_only |
| UTRN | ANKRD26 | 0.008 | 0.059 | bioplex_WMM youn_WMM gupta_WMM WMM_only boldt_WMM |
| DIXDC1 | ANKRD26 | 0.008 | 0.06 | bioplex_WMM WMM_only |
| ANKRD26 | CCSER1 | 0.008 | 0.06 | bioplex_WMM WMM_only |
| DISC1 | CCSER2 | 0.008 | 0.059 | bioplex_WMM youn_WMM WMM_only |
| ANKRD26 | PAFAH1B1 | 0.008 | 0.05 | bioplex_WMM gupta_WMM WMM_only |
| DISC1 | TRIM7 | 0.008 | 0.041 | bioplex_WMM WMM_only |
| UTRN | CCSER1 | 0.008 | 0.04 | bioplex_WMM WMM_only |
| DISC1 | NDE1 | 0.008 | 0.033 | bioplex_WMM WMM_only |
| NDE1 | TRIM7 | 0.008 | 0.023 | bioplex_WMM WMM_only |
| UTRN | PAFAH1B1 | 0.008 | 0.022 | bioplex_WMM gupta_WMM WMM_only |
| DISC1 | CCSER1 | 0.008 | 0.019 | bioplex_WMM WMM_only |
| DIXDC1 | DISC1 | 0.008 | 0.019 | bioplex_WMM WMM_only |
| DISC1 | PAFAH1B1 | 0.007 | 0.007 | bioplex_WMM WMM_only |
| DISC1 | ANKRD26 | 0.007 | 0.009 | bioplex_WMM youn_WMM WMM_only |
| NDE1 | UTRN | 0.007 | 0.012 | bioplex_WMM gupta_WMM WMM_only boldt_WMM |
| DIXDC1 | NDE1 | 0.007 | 0.004 | hein_WMM bioplex_WMM WMM_only |
| NDE1 | ANKRD26 | 0.007 | 0.003 | bioplex_WMM gupta_WMM WMM_only |
| DISC1 | UTRN | 0.007 | 0.006 | bioplex_WMM youn_WMM WMM_only |
| UTRN | ALDH9A1 | 0.007 | 0.002 | youn_WMM WMM_only |
| PAFAH1B1 | CCSER1 | 0.007 | 0.005 | bioplex (CCSER1) bioplex_WMM |
| CCSER1 | ALDH9A1 | 0.006 | 0.006 | bioplex (CCSER1) |
| SLC25A43 | ALDH9A1 | 0.006 | 0.001 | bioplex (SLC25A43) |
| UTRN | L3HYPDH | 0.006 | 0.006 | bioplex (L3HYPDH) bioplex_WMM |
| NDE1 | SLC25A43 | 0.005 | 0.011 | bioplex (SLC25A43) bioplex_WMM |
| CCSER2 | ANKRD26 | 0.0 | 0.012 | hein_WMM bioplex_WMM youn_WMM hein (ANKRD26) gupta_WMM |
| NDE1 | L3HYPDH | 0.0 | 0.0 | bioplex (L3HYPDH) bioplex_WMM |
Images
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Complex HuMAP2_00783 has an average edge precision of 0.181 which is ranked 6419 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PAFAH1B1 | HuMAP2_00783 HuMAP2_04820 |
| CCSER2 | HuMAP2_00460 HuMAP2_00783 HuMAP2_05796 |
| NDEL1 | HuMAP2_00460 HuMAP2_00783 HuMAP2_05796 |
| ALDH9A1 | HuMAP2_00783 HuMAP2_04384 HuMAP2_04578 HuMAP2_05032 HuMAP2_05568 |
| DIXDC1 | HuMAP2_00460 HuMAP2_00783 HuMAP2_03819 HuMAP2_05796 |
| TRIM7 | HuMAP2_00783 |
| CCSER1 | HuMAP2_00783 HuMAP2_02038 HuMAP2_04008 HuMAP2_04094 HuMAP2_06072 |
| UTRN | HuMAP2_00771 HuMAP2_00783 HuMAP2_05930 |
| L3HYPDH | HuMAP2_00783 HuMAP2_03819 |
| ANKRD26 | HuMAP2_00783 HuMAP2_01714 HuMAP2_01880 |
| DISC1 | HuMAP2_00460 HuMAP2_00783 |
| NDE1 | HuMAP2_00460 HuMAP2_00783 HuMAP2_05796 |
| SLC25A43 | HuMAP2_00783 HuMAP2_03885 HuMAP2_06150 HuMAP2_06914 |