hu.MAP 2.0: Complex View

Human Protein Complex Map

Complex: HuMAP2_00784

Confidence: High

Genename	Protein Name	Links
ARVCF	Armadillo repeat protein deleted in velo-cardio-facial syndrome	UniProt NCBI
CDH8	Cadherin-8	UniProt NCBI
CDH11	Cadherin-11 (OSF-4) (Osteoblast cadherin) (OB-cadherin)	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-418990	0.00234745427481	0.666666666667	CDH8 CDH11	Adherens junctions interactions
WP:WP4540	0.00357470816736	0.666666666667	CDH8 CDH11	Pathways Regulating Hippo Signaling
WP:WP4541	0.00491871423903	0.666666666667	CDH8 CDH11	Hippo-Merlin Signaling Dysregulation
REAC:R-HSA-421270	0.00632193682699	0.666666666667	CDH8 CDH11	Cell-cell junction organization
GO:0005913	0.0103137207675	1.0	ARVCF CDH11 CDH8	cell-cell adherens junction
GO:0007043	0.0110330947082	1.0	ARVCF CDH11 CDH8	cell-cell junction assembly
REAC:R-HSA-446728	0.0165866686159	0.666666666667	CDH8 CDH11	Cell junction organization
HP:0000363	0.0183346678183	0.666666666667	ARVCF CDH11	Abnormality of earlobe
GO:0045216	0.0196004650773	1.0	ARVCF CDH11 CDH8	cell-cell junction organization
REAC:R-HSA-1500931	0.0350118981581	0.666666666667	CDH8 CDH11	Cell-Cell communication

Protein 1	Protein 2	Score	Precision	Evidence
CDH8	CDH11	0.962	0.87	bioplex (CDH8) bioplex_WMM
ARVCF	CDH8	0.518	0.632	bioplex (CDH8) bioplex_WMM
ARVCF	CDH11	0.008	0.066	bioplex_WMM WMM_only

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ComplexPrecisionDistribution

Complex HuMAP2_00784 has an average edge precision of 0.523 which is ranked 2383 out of all 6965 complexes.

Related Complexes

Genename	Complexes
ARVCF	HuMAP2_00784 HuMAP2_04808 HuMAP2_05814
CDH8	HuMAP2_00784 HuMAP2_01438 HuMAP2_03148 HuMAP2_04808 HuMAP2_05814
CDH11	HuMAP2_00784 HuMAP2_01438 HuMAP2_03148 HuMAP2_04808 HuMAP2_05814