hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00787
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CRYZ | Quinone oxidoreductase (EC 1.6.5.5) (NADPH:quinone reductase) (Zeta-crystallin) | UniProt NCBI |
| GOT2 | Aspartate aminotransferase, mitochondrial (mAspAT) (EC 2.6.1.1) (EC 2.6.1.7) (Fatty acid-binding protein) (FABP-1) (Glutamate oxaloacetate transaminase 2) (Kynurenine aminotransferase 4) (Kynurenine aminotransferase IV) (Kynurenine--oxoglutarate transaminase 4) (Kynurenine--oxoglutarate transaminase IV) (Plasma membrane-associated fatty acid-binding protein) (FABPpm) (Transaminase A) | UniProt NCBI |
| ACO2 | Aconitate hydratase, mitochondrial (Aconitase) (EC 4.2.1.3) (Citrate hydro-lyase) | UniProt NCBI |
| PGM1 | Phosphoglucomutase-1 (PGM 1) (EC 5.4.2.2) (Glucose phosphomutase 1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:01210 | 0.000272131870234 | 0.5 | GOT2 ACO2 | 2-Oxocarboxylic acid metabolism |
| WP:WP4290 | 0.00144137960059 | 0.5 | GOT2 ACO2 | Metabolic reprogramming in colon cancer |
| KEGG:01230 | 0.00494838688052 | 0.5 | GOT2 ACO2 | Biosynthesis of amino acids |
| WP:WP3925 | 0.0063819591539 | 0.5 | GOT2 ACO2 | Amino Acid metabolism |
| KEGG:01200 | 0.012776519361 | 0.5 | GOT2 ACO2 | Carbon metabolism |
| KEGG:00400 | 0.0397753158041 | 0.25 | GOT2 | Phenylalanine, tyrosine and tryptophan biosynthesis |
| REAC:R-HSA-5609974 | 0.0499190562503 | 0.25 | PGM1 | Defective PGM1 causes PGM1-CDG (CDG1t) |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ACO2 | GOT2 | 0.981 | 0.896 | bioplex (GOT2) bioplex_WMM fraction treiber_WMM |
| PGM1 | ACO2 | 0.823 | 0.774 | bioplex_WMM fraction |
| CRYZ | ACO2 | 0.798 | 0.764 | bioplex_WMM fraction |
| CRYZ | PGM1 | 0.007 | 0.009 | bioplex_WMM WMM_only treiber_WMM |
| PGM1 | GOT2 | 0.0 | 0.001 | bioplex (GOT2) bioplex_WMM fraction treiber_WMM |
| CRYZ | GOT2 | 0.0 | 0.001 | bioplex (GOT2) bioplex_WMM fraction treiber_WMM |
Images
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Complex HuMAP2_00787 has an average edge precision of 0.407 which is ranked 3229 out of all 6965 complexes.
Related Complexes