hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00791
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RACGAP1 | Rac GTPase-activating protein 1 (Male germ cell RacGap) (MgcRacGAP) (Protein CYK4 homolog) (CYK4) (HsCYK-4) | UniProt NCBI |
| KIF23 | Kinesin-like protein KIF23 (Kinesin-like protein 5) (Mitotic kinesin-like protein 1) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:7440 | 1.67592346237e-06 | 1.0 | KIF23 RACGAP1 | KIF23-RACGAP1 complex |
| CORUM:7439 | 5.02777038712e-06 | 1.0 | KIF23 RACGAP1 | ECT2-KIF23-RACGAP1 complex |
| CORUM:929 | 0.00111616502594 | 1.0 | KIF23 RACGAP1 | CEN complex |
| GO:0097149 | 0.00135247023414 | 1.0 | KIF23 RACGAP1 | centralspindlin complex |
| REAC:R-HSA-983189 | 0.00267477384595 | 1.0 | KIF23 RACGAP1 | Kinesins |
| REAC:R-HSA-6811434 | 0.00764221098843 | 1.0 | KIF23 RACGAP1 | COPI-dependent Golgi-to-ER retrograde traffic |
| GO:0051256 | 0.00946729163895 | 1.0 | KIF23 RACGAP1 | mitotic spindle midzone assembly |
| REAC:R-HSA-2132295 | 0.011178409494 | 1.0 | KIF23 RACGAP1 | MHC class II antigen presentation |
| GO:0051255 | 0.0126230555186 | 1.0 | KIF23 RACGAP1 | spindle midzone assembly |
| REAC:R-HSA-8856688 | 0.014052618232 | 1.0 | KIF23 RACGAP1 | Golgi-to-ER retrograde transport |
| GO:0000022 | 0.0162296428096 | 1.0 | KIF23 RACGAP1 | mitotic spindle elongation |
| GO:0051231 | 0.0162296428096 | 1.0 | KIF23 RACGAP1 | spindle elongation |
| REAC:R-HSA-983231 | 0.0210512746109 | 1.0 | KIF23 RACGAP1 | Factors involved in megakaryocyte development and platelet production |
| MIRNA:hsa-miR-4310 | 0.0287467819846 | 1.0 | KIF23 RACGAP1 | hsa-miR-4310 |
| MIRNA:hsa-miR-7157-5p | 0.0287467819846 | 1.0 | KIF23 RACGAP1 | hsa-miR-7157-5p |
| REAC:R-HSA-6811442 | 0.0323553783646 | 1.0 | KIF23 RACGAP1 | Intra-Golgi and retrograde Golgi-to-ER traffic |
| HP:0025035 | 0.0497341708567 | 0.5 | KIF23 | Abnormal proerythroblast morphology |
| HP:0025196 | 0.0497341708567 | 0.5 | KIF23 | Increased total iron binding capacity |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RACGAP1 | KIF23 | 1.0 | 0.949 | hein_WMM bioplex (RACGAP1) bioplex_WMM Guru youn_WMM hein (KIF23,RACGAP1) Malo gupta_WMM fraction boldt_WMM treiber_WMM |
Images
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Complex HuMAP2_00791 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RACGAP1 | HuMAP2_00791 HuMAP2_01667 HuMAP2_02358 HuMAP2_02551 HuMAP2_04335 HuMAP2_05003 HuMAP2_05682 HuMAP2_06648 |
| KIF23 | HuMAP2_00791 HuMAP2_01667 HuMAP2_02358 HuMAP2_02551 HuMAP2_04335 HuMAP2_05003 HuMAP2_05682 HuMAP2_06648 |