hu.MAP 2.0: Complex View

Human Protein Complex Map

Genename	Protein Name	Links
SLC30A5	Zinc transporter 5 (ZnT-5) (Solute carrier family 30 member 5) (ZnT-like transporter 1) (hZTL1)	UniProt NCBI
GLG1	Golgi apparatus protein 1 (CFR-1) (Cysteine-rich fibroblast growth factor receptor) (E-selectin ligand 1) (ESL-1) (Golgi sialoglycoprotein MG-160)	UniProt NCBI
SPPL2B	Signal peptide peptidase-like 2B (SPP-like 2B) (SPPL2b) (EC 3.4.23.-) (Intramembrane protease 4) (IMP-4) (Presenilin homologous protein 4) (PSH4) (Presenilin-like protein 1)	UniProt NCBI
MTCH1	Mitochondrial carrier homolog 1 (Presenilin-associated protein)	UniProt NCBI
PIGN	GPI ethanolamine phosphate transferase 1 (EC 2.-.-.-) (MCD4 homolog) (Phosphatidylinositol-glycan biosynthesis class N protein) (PIG-N)	UniProt NCBI
FXYD6	FXYD domain-containing ion transport regulator 6 (Phosphohippolin)	UniProt NCBI
COX14	Cytochrome c oxidase assembly protein COX14	UniProt NCBI
SLC30A6	Zinc transporter 6 (ZnT-6) (Solute carrier family 30 member 6)	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
REAC:R-HSA-435368	0.000670718000013	0.25	SLC30A5 SLC30A6	Zinc efflux and compartmentalization by the SLC30 family
WP:WP3529	0.00321423512458	0.25	SLC30A5 SLC30A6	Zinc homeostasis
REAC:R-HSA-435354	0.00468368688758	0.25	SLC30A5 SLC30A6	Zinc transporters
REAC:R-HSA-425410	0.00935228350379	0.25	SLC30A5 SLC30A6	Metal ion SLC transporters
REAC:R-HSA-264876	0.0122816673814	0.25	SLC30A5 SLC30A6	Insulin processing
HPA:022010_21	0.0242250489628	0.75	FXYD6 SLC30A5 COX14 MTCH1 SPPL2B PIGN	hippocampus; glial cells[Approved,Low]

Protein 1	Protein 2	Score	Precision	Evidence
SPPL2B	SLC30A5	0.08	0.35	bioplex (SPPL2B) bioplex_WMM
SPPL2B	COX14	0.045	0.283	bioplex (SPPL2B) bioplex_WMM
GLG1	SPPL2B	0.044	0.278	bioplex (SPPL2B) bioplex_WMM
SPPL2B	PIGN	0.043	0.269	bioplex (SPPL2B) bioplex_WMM
SPPL2B	SLC30A6	0.041	0.269	bioplex (SPPL2B) bioplex_WMM
SPPL2B	MTCH1	0.034	0.261	bioplex (SPPL2B) bioplex_WMM
SLC30A5	SLC30A6	0.026	0.218	bioplex_WMM youn_WMM gupta_WMM WMM_only boldt_WMM
SPPL2B	FXYD6	0.021	0.188	bioplex (SPPL2B) bioplex_WMM
FXYD6	COX14	0.008	0.091	bioplex_WMM WMM_only
PIGN	COX14	0.008	0.046	bioplex_WMM WMM_only
COX14	SLC30A6	0.008	0.028	bioplex_WMM WMM_only
COX14	SLC30A5	0.008	0.026	bioplex_WMM WMM_only
PIGN	FXYD6	0.008	0.029	bioplex_WMM WMM_only
FXYD6	SLC30A6	0.007	0.01	bioplex_WMM WMM_only
FXYD6	SLC30A5	0.007	0.005	bioplex_WMM WMM_only
MTCH1	COX14	0.007	0.008	bioplex_WMM WMM_only
PIGN	SLC30A6	0.007	0.005	bioplex_WMM WMM_only
GLG1	COX14	0.007	0.005	bioplex_WMM WMM_only
PIGN	SLC30A5	0.007	0.002	bioplex_WMM WMM_only
FXYD6	MTCH1	0.007	0.006	bioplex_WMM WMM_only
GLG1	FXYD6	0.007	0.002	bioplex_WMM WMM_only
PIGN	MTCH1	0.007	0.002	bioplex_WMM WMM_only
GLG1	PIGN	0.007	0.005	bioplex_WMM WMM_only
MTCH1	SLC30A6	0.006	0.002	bioplex_WMM WMM_only
GLG1	SLC30A6	0.006	0.004	bioplex_WMM WMM_only
MTCH1	SLC30A5	0.006	0.003	bioplex_WMM WMM_only
GLG1	MTCH1	0.006	0.004	bioplex_WMM WMM_only
GLG1	SLC30A5	0.006	0.007	bioplex_WMM WMM_only

Click to enlarge

Complex HuMAP2_00807 has an average edge precision of 0.086 which is ranked 6959 out of all 6965 complexes.