hu.MAP 2.0: Complex View
Human Protein Complex Map
Search for a protein
Complex: HuMAP2_00809
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CDK5RAP3 | CDK5 regulatory subunit-associated protein 3 (CDK5 activator-binding protein C53) (LXXLL/leucine-zipper-containing ARF-binding protein) (Protein HSF-27) | UniProt NCBI |
| UFL1 | E3 UFM1-protein ligase 1 (EC 2.3.2.-) (E3 UFM1-protein transferase 1) (Multiple alpha-helix protein located at ER) (Novel LZAP-binding protein) (Regulator of C53/LZAP and DDRGK1) | UniProt NCBI |
| DDRGK1 | DDRGK domain-containing protein 1 (Dashurin) (UFM1-binding and PCI domain-containing protein 1) | UniProt NCBI |
| ISYNA1 | Inositol-3-phosphate synthase 1 (IPS 1) (EC 5.5.1.4) (Myo-inositol 1-phosphate synthase) (MI-1-P synthase) (MIP synthase) (hIPS) (Myo-inositol 1-phosphate synthase A1) (hINO1) | UniProt NCBI |
| SPARC | SPARC (Basement-membrane protein 40) (BM-40) (Osteonectin) (ON) (Secreted protein acidic and rich in cysteine) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0071569 | 1.81582264982e-05 | 0.6 | CDK5RAP3 DDRGK1 UFL1 | protein ufmylation |
| GO:1990564 | 0.0450641792523 | 0.4 | DDRGK1 UFL1 | protein polyufmylation |
| GO:1990592 | 0.0450641792523 | 0.4 | DDRGK1 UFL1 | protein K69-linked ufmylation |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DDRGK1 | UFL1 | 1.0 | 0.949 | hein_WMM bioplex (DDRGK1) bioplex_WMM youn_WMM hein (UFL1) gupta_WMM |
| UFL1 | CDK5RAP3 | 0.991 | 0.909 | hein_WMM bioplex (CDK5RAP3) bioplex_WMM youn_WMM hein (UFL1) |
| DDRGK1 | CDK5RAP3 | 0.874 | 0.807 | hein_WMM bioplex (CDK5RAP3,DDRGK1) bioplex_WMM youn_WMM gupta_WMM |
| DDRGK1 | ISYNA1 | 0.026 | 0.218 | bioplex_WMM youn_WMM fraction |
| SPARC | ISYNA1 | 0.021 | 0.189 | fraction |
| UFL1 | ISYNA1 | 0.007 | 0.002 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| CDK5RAP3 | ISYNA1 | 0.007 | 0.001 | bioplex_WMM WMM_only |
| SPARC | CDK5RAP3 | 0.0 | 0.015 | fraction |
| SPARC | DDRGK1 | 0.0 | 0.009 | fraction |
Images
Click to enlarge
Complex HuMAP2_00809 has an average edge precision of 0.344 which is ranked 4063 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CDK5RAP3 | HuMAP2_00809 HuMAP2_01895 HuMAP2_03733 |
| UFL1 | HuMAP2_00809 HuMAP2_01895 HuMAP2_03733 |
| DDRGK1 | HuMAP2_00809 HuMAP2_01895 HuMAP2_03733 |
| ISYNA1 | HuMAP2_00809 HuMAP2_01418 |
| SPARC | HuMAP2_00604 HuMAP2_00809 HuMAP2_02186 HuMAP2_02630 |