hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00810
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| TSPAN7 | Tetraspanin-7 (Tspan-7) (Cell surface glycoprotein A15) (Membrane component chromosome X surface marker 1) (T-cell acute lymphoblastic leukemia-associated antigen 1) (TALLA-1) (Transmembrane 4 superfamily member 2) (CD antigen CD231) | UniProt NCBI |
| PHLPP1 | PH domain leucine-rich repeat-containing protein phosphatase 1 (EC 3.1.3.16) (Pleckstrin homology domain-containing family E member 1) (PH domain-containing family E member 1) (Suprachiasmatic nucleus circadian oscillatory protein) (hSCOP) | UniProt NCBI |
| DIP2A | Disco-interacting protein 2 homolog A (DIP2 homolog A) | UniProt NCBI |
| MAP3K21 | Mitogen-activated protein kinase kinase kinase 21 (EC 2.7.11.25) (Mitogen-activated protein kinase kinase kinase MLK4) (Mixed lineage kinase 4) | UniProt NCBI |
| HAVCR2 | Hepatitis A virus cellular receptor 2 (HAVcr-2) (T-cell immunoglobulin and mucin domain-containing protein 3) (TIMD-3) (T-cell immunoglobulin mucin receptor 3) (TIM-3) (T-cell membrane protein 3) (CD antigen CD366) | UniProt NCBI |
| RPS6KC1 | Ribosomal protein S6 kinase delta-1 (S6K-delta-1) (EC 2.7.11.1) (52 kDa ribosomal protein S6 kinase) (Ribosomal S6 kinase-like protein with two PSK domains 118 kDa protein) (SPHK1-binding protein) | UniProt NCBI |
| DENND6A | Protein DENND6A (DENN domain-containing protein 6A) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| HAVCR2 | TSPAN7 | 0.109 | 0.378 | bioplex (HAVCR2) bioplex_WMM |
| HAVCR2 | PHLPP1 | 0.065 | 0.347 | bioplex (HAVCR2) bioplex_WMM |
| MAP3K21 | HAVCR2 | 0.06 | 0.337 | bioplex (HAVCR2) bioplex_WMM |
| HAVCR2 | DENND6A | 0.028 | 0.23 | bioplex (HAVCR2) bioplex_WMM |
| HAVCR2 | DIP2A | 0.022 | 0.208 | bioplex (HAVCR2) bioplex_WMM |
| RPS6KC1 | DENND6A | 0.02 | 0.184 | hein_WMM hein (DENND6A) |
| DIP2A | DENND6A | 0.011 | 0.145 | bioplex_WMM youn_WMM WMM_only |
| MAP3K21 | TSPAN7 | 0.008 | 0.087 | bioplex_WMM WMM_only |
| TSPAN7 | PHLPP1 | 0.008 | 0.082 | bioplex_WMM WMM_only |
| PHLPP1 | DENND6A | 0.008 | 0.061 | bioplex_WMM WMM_only |
| MAP3K21 | PHLPP1 | 0.008 | 0.029 | bioplex_WMM WMM_only |
| TSPAN7 | DENND6A | 0.008 | 0.029 | bioplex_WMM WMM_only |
| TSPAN7 | DIP2A | 0.007 | 0.007 | bioplex_WMM WMM_only |
| MAP3K21 | DENND6A | 0.007 | 0.01 | bioplex_WMM WMM_only |
| PHLPP1 | DIP2A | 0.007 | 0.003 | bioplex_WMM WMM_only |
| MAP3K21 | DIP2A | 0.007 | 0.003 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_00810 has an average edge precision of 0.134 which is ranked 6811 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| TSPAN7 | HuMAP2_00810 HuMAP2_03555 |
| PHLPP1 | HuMAP2_00810 HuMAP2_01079 HuMAP2_03555 |
| DIP2A | HuMAP2_00810 |
| MAP3K21 | HuMAP2_00810 HuMAP2_03555 HuMAP2_04969 |
| HAVCR2 | HuMAP2_00810 HuMAP2_03555 |
| RPS6KC1 | HuMAP2_00810 HuMAP2_04274 HuMAP2_06786 |
| DENND6A | HuMAP2_00810 HuMAP2_06786 |