hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00816
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ERLEC1 | Endoplasmic reticulum lectin 1 (ER lectin) (Erlectin) (XTP3-transactivated gene B protein) | UniProt NCBI |
| SEL1L | Protein sel-1 homolog 1 (Suppressor of lin-12-like protein 1) (Sel-1L) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6859 | 0.000130722030065 | 1.0 | SEL1L ERLEC1 | HRD1 complex |
| KEGG:04141 | 0.00178666132548 | 1.0 | SEL1L ERLEC1 | Protein processing in endoplasmic reticulum |
| REAC:R-HSA-5362768 | 0.00248874634163 | 1.0 | SEL1L ERLEC1 | Hh mutants that don't undergo autocatalytic processing are degraded by ERAD |
| REAC:R-HSA-5387390 | 0.00267477384595 | 1.0 | SEL1L ERLEC1 | Hh mutants abrogate ligand secretion |
| REAC:R-HSA-5678895 | 0.0029663845284 | 1.0 | SEL1L ERLEC1 | Defective CFTR causes cystic fibrosis |
| REAC:R-HSA-5358346 | 0.00316917126735 | 1.0 | SEL1L ERLEC1 | Hedgehog ligand biogenesis |
| REAC:R-HSA-5619084 | 0.00477638186777 | 1.0 | SEL1L ERLEC1 | ABC transporter disorders |
| REAC:R-HSA-382556 | 0.00812990471598 | 1.0 | SEL1L ERLEC1 | ABC-family proteins mediated transport |
| REAC:R-HSA-5358351 | 0.0167776697818 | 1.0 | SEL1L ERLEC1 | Signaling by Hedgehog |
| REAC:R-HSA-5619115 | 0.0202619146601 | 1.0 | SEL1L ERLEC1 | Disorders of transmembrane transporters |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ERLEC1 | SEL1L | 1.0 | 0.949 | hein_WMM bioplex (ERLEC1) hein (SEL1L) gupta_WMM boldt_WMM bioplex_WMM |
Images
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Complex HuMAP2_00816 has an average edge precision of 0.949 which is ranked 5 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ERLEC1 | HuMAP2_00816 HuMAP2_01997 HuMAP2_06289 HuMAP2_06933 |
| SEL1L | HuMAP2_00816 HuMAP2_01997 HuMAP2_06289 HuMAP2_06933 |