hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00837
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| GOSR1 | Golgi SNAP receptor complex member 1 (28 kDa Golgi SNARE protein) (28 kDa cis-Golgi SNARE p28) (GOS-28) | UniProt NCBI |
| VAMP2 | Vesicle-associated membrane protein 2 (VAMP-2) (Synaptobrevin-2) | UniProt NCBI |
| STX8 | Syntaxin-8 | UniProt NCBI |
| SNAP29 | Synaptosomal-associated protein 29 (SNAP-29) (Soluble 29 kDa NSF attachment protein) (Vesicle-membrane fusion protein SNAP-29) | UniProt NCBI |
| STX7 | Syntaxin-7 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:04130 | 1.57110254975e-12 | 1.0 | SNAP29 STX7 STX8 VAMP2 GOSR1 | SNARE interactions in vesicular transport |
| GO:0031201 | 1.12291179669e-08 | 1.0 | SNAP29 STX7 STX8 VAMP2 GOSR1 | SNARE complex |
| GO:0061025 | 1.20260182295e-06 | 1.0 | SNAP29 STX7 STX8 VAMP2 GOSR1 | membrane fusion |
| GO:0005484 | 3.33813219873e-06 | 0.8 | SNAP29 STX7 STX8 GOSR1 | SNAP receptor activity |
| GO:0019905 | 3.84719751497e-05 | 0.8 | SNAP29 VAMP2 STX8 STX7 | syntaxin binding |
| GO:0006906 | 0.000125031076937 | 0.8 | SNAP29 STX7 STX8 GOSR1 | vesicle fusion |
| GO:0090174 | 0.000173300430897 | 0.8 | SNAP29 STX7 STX8 GOSR1 | organelle membrane fusion |
| GO:0000149 | 0.000296464073962 | 0.8 | SNAP29 VAMP2 STX8 STX7 | SNARE binding |
| GO:0048284 | 0.000438392708191 | 0.8 | SNAP29 STX7 STX8 GOSR1 | organelle fusion |
| GO:0061024 | 0.00600585321961 | 1.0 | SNAP29 STX7 STX8 VAMP2 GOSR1 | membrane organization |
| REAC:R-HSA-6811438 | 0.0126969553517 | 0.4 | SNAP29 GOSR1 | Intra-Golgi traffic |
| MIRNA:hsa-miR-6731-3p | 0.0162837213155 | 0.4 | GOSR1 STX7 | hsa-miR-6731-3p |
| GO:0016050 | 0.0252719643298 | 0.8 | SNAP29 STX7 STX8 GOSR1 | vesicle organization |
| GO:0098796 | 0.0328678033498 | 1.0 | SNAP29 STX7 STX8 VAMP2 GOSR1 | membrane protein complex |
| MIRNA:hsa-miR-26a-2-3p | 0.0390630814684 | 0.4 | GOSR1 STX7 | hsa-miR-26a-2-3p |
| MIRNA:hsa-miR-3663-3p | 0.040531706351 | 0.4 | SNAP29 GOSR1 | hsa-miR-3663-3p |
| CORUM:873 | 0.0499494897235 | 0.2 | SNAP29 | SNARE complex (STX1A, SNAP29) |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| STX7 | SNAP29 | 1.0 | 0.949 | hein_WMM bioplex (STX7) bioplex_WMM Guru youn_WMM hein (SNAP29) gupta_WMM fraction |
| GOSR1 | STX7 | 0.992 | 0.913 | hein_WMM bioplex (STX7) bioplex_WMM youn_WMM gupta_WMM |
| STX7 | VAMP2 | 0.923 | 0.844 | hein_WMM bioplex (STX7) bioplex_WMM Guru hein (VAMP2) gupta_WMM fraction |
| STX8 | STX7 | 0.84 | 0.784 | hein_WMM bioplex (STX7) bioplex_WMM youn_WMM gupta_WMM |
| GOSR1 | STX8 | 0.017 | 0.171 | hein_WMM bioplex_WMM youn_WMM gupta_WMM WMM_only |
| GOSR1 | SNAP29 | 0.007 | 0.007 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| GOSR1 | VAMP2 | 0.006 | 0.002 | bioplex_WMM gupta_WMM WMM_only |
| STX8 | VAMP2 | 0.006 | 0.006 | bioplex_WMM gupta_WMM WMM_only |
| STX8 | SNAP29 | 0.006 | 0.004 | hein_WMM bioplex_WMM youn_WMM hein (SNAP29) gupta_WMM |
| SNAP29 | VAMP2 | 0.005 | 0.008 | bioplex_WMM gupta_WMM WMM_only |
Images
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Complex HuMAP2_00837 has an average edge precision of 0.369 which is ranked 3655 out of all 6965 complexes.
Related Complexes