hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00856
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SLCO1B1 | Solute carrier organic anion transporter family member 1B1 (Liver-specific organic anion transporter 1) (LST-1) (OATP-C) (Sodium-independent organic anion-transporting polypeptide 2) (OATP-2) (Solute carrier family 21 member 6) | UniProt NCBI |
| SLC30A5 | Zinc transporter 5 (ZnT-5) (Solute carrier family 30 member 5) (ZnT-like transporter 1) (hZTL1) | UniProt NCBI |
| SETD9 | SET domain-containing protein 9 (EC 2.1.1.-) | UniProt NCBI |
| USO1 | General vesicular transport factor p115 (Protein USO1 homolog) (Transcytosis-associated protein) (TAP) (Vesicle-docking protein) | UniProt NCBI |
| BLZF1 | Golgin-45 (Basic leucine zipper nuclear factor 1) (JEM-1) (p45 basic leucine-zipper nuclear factor) | UniProt NCBI |
| SLC30A6 | Zinc transporter 6 (ZnT-6) (Solute carrier family 30 member 6) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-435368 | 0.000332336489066 | 0.333333333333 | SLC30A5 SLC30A6 | Zinc efflux and compartmentalization by the SLC30 family |
| WP:WP3529 | 0.00140863716749 | 0.333333333333 | SLC30A5 SLC30A6 | Zinc homeostasis |
| REAC:R-HSA-162658 | 0.00172598429993 | 0.333333333333 | USO1 BLZF1 | Golgi Cisternae Pericentriolar Stack Reorganization |
| REAC:R-HSA-435354 | 0.00232260810736 | 0.333333333333 | SLC30A5 SLC30A6 | Zinc transporters |
| REAC:R-HSA-425410 | 0.00464022545552 | 0.333333333333 | SLC30A5 SLC30A6 | Metal ion SLC transporters |
| REAC:R-HSA-264876 | 0.0060953046166 | 0.333333333333 | SLC30A5 SLC30A6 | Insulin processing |
| REAC:R-HSA-425407 | 0.00611221514505 | 0.5 | SLC30A6 SLC30A5 SLCO1B1 | SLC-mediated transmembrane transport |
| REAC:R-HSA-425366 | 0.036283735834 | 0.333333333333 | SLC30A5 SLC30A6 | Transport of bile salts and organic acids, metal ions and amine compounds |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| USO1 | SLCO1B1 | 0.248 | 0.471 | bioplex (SLCO1B1) bioplex_WMM |
| BLZF1 | USO1 | 0.043 | 0.272 | hein_WMM hein (USO1) gupta_WMM |
| SLC30A6 | USO1 | 0.04 | 0.268 | hein_WMM youn_WMM hein (USO1) gupta_WMM |
| SLC30A5 | SLC30A6 | 0.026 | 0.218 | bioplex_WMM youn_WMM gupta_WMM WMM_only boldt_WMM |
| SETD9 | USO1 | 0.021 | 0.187 | bioplex (SETD9) bioplex_WMM |
| BLZF1 | SLC30A6 | 0.008 | 0.051 | hein_WMM gupta_WMM WMM_only |
| BLZF1 | SLC30A5 | 0.007 | 0.002 | gupta_WMM WMM_only |
| SLC30A5 | USO1 | 0.007 | 0.008 | youn_WMM gupta_WMM WMM_only |
Images
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Complex HuMAP2_00856 has an average edge precision of 0.185 which is ranked 6383 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| SLCO1B1 | HuMAP2_00856 HuMAP2_03815 HuMAP2_04798 HuMAP2_05608 |
| SLC30A5 | HuMAP2_00807 HuMAP2_00856 HuMAP2_02002 HuMAP2_05608 |
| SETD9 | HuMAP2_00856 HuMAP2_05608 |
| USO1 | HuMAP2_00856 HuMAP2_03815 HuMAP2_04798 HuMAP2_05608 |
| BLZF1 | HuMAP2_00079 HuMAP2_00856 HuMAP2_03815 HuMAP2_05608 HuMAP2_06174 |
| SLC30A6 | HuMAP2_00807 HuMAP2_00856 HuMAP2_02002 HuMAP2_05608 |