hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00858
Confidence: Extremely High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| HOMER1 | Homer protein homolog 1 (Homer-1) | UniProt NCBI |
| HOMER3 | Homer protein homolog 3 (Homer-3) | UniProt NCBI |
| HOMER2 | Homer protein homolog 2 (Homer-2) (Cupidin) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0035256 | 9.08185760231e-07 | 1.0 | HOMER2 HOMER3 HOMER1 | G protein-coupled glutamate receptor binding |
| KEGG:04724 | 4.86270322614e-06 | 1.0 | HOMER2 HOMER3 HOMER1 | Glutamatergic synapse |
| GO:2001256 | 5.08584025729e-06 | 1.0 | HOMER2 HOMER3 HOMER1 | regulation of store-operated calcium entry |
| KEGG:04068 | 7.23132386252e-06 | 1.0 | HOMER2 HOMER3 HOMER1 | FoxO signaling pathway |
| REAC:R-HSA-6794361 | 1.05322572372e-05 | 1.0 | HOMER2 HOMER3 HOMER1 | Neurexins and neuroligins |
| GO:0007216 | 2.59741127426e-05 | 1.0 | HOMER2 HOMER3 HOMER1 | G protein-coupled glutamate receptor signaling pathway |
| GO:0002115 | 3.30579616724e-05 | 1.0 | HOMER2 HOMER3 HOMER1 | store-operated calcium entry |
| REAC:R-HSA-6794362 | 3.8359608447e-05 | 1.0 | HOMER2 HOMER3 HOMER1 | Protein-protein interactions at synapses |
| GO:0035254 | 4.13224520905e-05 | 1.0 | HOMER2 HOMER3 HOMER1 | glutamate receptor binding |
| REAC:R-HSA-112316 | 0.0029451340212 | 1.0 | HOMER2 HOMER3 HOMER1 | Neuronal System |
| GO:0007215 | 0.00415585803882 | 1.0 | HOMER2 HOMER3 HOMER1 | glutamate receptor signaling pathway |
| GO:0014069 | 0.033252767518 | 1.0 | HOMER2 HOMER3 HOMER1 | postsynaptic density |
| GO:0051924 | 0.0356085105614 | 1.0 | HOMER2 HOMER3 HOMER1 | regulation of calcium ion transport |
| GO:0032279 | 0.0364177948924 | 1.0 | HOMER2 HOMER3 HOMER1 | asymmetric synapse |
| GO:0099572 | 0.0364177948924 | 1.0 | HOMER2 HOMER3 HOMER1 | postsynaptic specialization |
| GO:0098984 | 0.0372392489125 | 1.0 | HOMER2 HOMER3 HOMER1 | neuron to neuron synapse |
| GO:0001664 | 0.0490669153423 | 1.0 | HOMER2 HOMER3 HOMER1 | G protein-coupled receptor binding |
| CORUM:74 | 0.0499776345577 | 0.333333333333 | HOMER3 | HOMER3-IP3R-TRPC1 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| HOMER3 | HOMER1 | 1.0 | 0.949 | hein_WMM bioplex (HOMER1,HOMER3) bioplex_WMM hein (HOMER1) |
| HOMER2 | HOMER1 | 1.0 | 0.949 | bioplex (HOMER1) bioplex_WMM |
| HOMER3 | HOMER2 | 0.929 | 0.845 | bioplex (HOMER3) bioplex_WMM |
Images
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Complex HuMAP2_00858 has an average edge precision of 0.914 which is ranked 495 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| HOMER1 | HuMAP2_00858 HuMAP2_01085 HuMAP2_03401 HuMAP2_04707 HuMAP2_06084 HuMAP2_06825 |
| HOMER3 | HuMAP2_00858 HuMAP2_01085 HuMAP2_03401 HuMAP2_04707 HuMAP2_06084 HuMAP2_06825 |
| HOMER2 | HuMAP2_00858 HuMAP2_01085 HuMAP2_03401 HuMAP2_04707 HuMAP2_06084 HuMAP2_06825 |