hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00859
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| PTPN2 | Tyrosine-protein phosphatase non-receptor type 2 (EC 3.1.3.48) (T-cell protein-tyrosine phosphatase) (TCPTP) | UniProt NCBI |
| COL5A1 | Collagen alpha-1(V) chain | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| REAC:R-HSA-6806834 | 0.00440432685912 | 1.0 | PTPN2 COL5A1 | Signaling by MET |
| HP:0000689 | 0.0108197618731 | 1.0 | PTPN2 COL5A1 | Dental malocclusion |
| HP:0001369 | 0.0435495415392 | 1.0 | PTPN2 COL5A1 | Arthritis |
| HP:0005100 | 0.0497341708567 | 0.5 | COL5A1 | Premature birth following premature rupture of fetal membranes |
| HP:0006316 | 0.0497341708567 | 0.5 | COL5A1 | Irregularly spaced teeth |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| PTPN2 | COL5A1 | 0.723 | 0.733 | hein_WMM bioplex (PTPN2) bioplex_WMM hein (PTPN2) |
Images
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Complex HuMAP2_00859 has an average edge precision of 0.733 which is ranked 1248 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| PTPN2 | HuMAP2_00416 HuMAP2_00859 HuMAP2_04566 HuMAP2_04914 |
| COL5A1 | HuMAP2_00859 HuMAP2_04566 HuMAP2_05432 HuMAP2_05533 |