hu.MAP 2.0: Complex View

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0000808	2.75202561382e-12	0.833333333333	ORC2 ORC5 ORC3 LRWD1 ORC6	origin recognition complex
GO:0005664	2.75202561382e-12	0.833333333333	ORC2 ORC5 ORC3 LRWD1 ORC6	nuclear origin of replication recognition complex
CORUM:1033	6.80871178609e-12	0.666666666667	ORC5 ORC2 ORC3 ORC6	ORC complex (origin recognition complex)
CORUM:1031	6.80871178609e-12	0.666666666667	ORC5 ORC2 ORC3 ORC6	ORC complex (origin recognition complex)
CORUM:389	6.80871178609e-12	0.666666666667	ORC5 ORC2 ORC3 ORC6	ORC complex (origin recognition complex)
REAC:R-HSA-68616	1.79928580314e-11	0.666666666667	ORC5 ORC2 ORC3 ORC6	Assembly of the ORC complex at the origin of replication
REAC:R-HSA-113507	1.51091283076e-10	0.666666666667	ORC5 ORC2 ORC3 ORC6	E2F-enabled inhibition of pre-replication complex formation
REAC:R-HSA-68689	3.95630202777e-10	0.666666666667	ORC5 ORC2 ORC3 ORC6	CDC6 association with the ORC:origin complex
GO:0006270	6.9945924325e-09	0.833333333333	ORC2 ORC5 ORC3 LRWD1 ORC6	DNA replication initiation
REAC:R-HSA-113510	8.75943607526e-09	0.666666666667	ORC5 ORC2 ORC3 ORC6	E2F mediated regulation of DNA replication
CORUM:1034	9.01288868683e-09	0.5	ORC5 ORC2 ORC3	ORC 2-5 complex (origin recognition 2-5 complex)
CORUM:1038	2.25288169953e-08	0.5	ORC5 ORC2 ORC3	ORC 1-5 complex (origin recognition 1-5 complex)
WP:WP466	3.37122762341e-08	0.666666666667	ORC5 ORC2 ORC3 ORC6	DNA Replication
CORUM:5251	4.50508252789e-08	0.5	ORC6 ORC2 ORC3	Ku-ORC complex
REAC:R-HSA-68962	4.89421979513e-08	0.666666666667	ORC5 ORC2 ORC3 ORC6	Activation of the pre-replicative complex
REAC:R-HSA-176187	7.89588505076e-08	0.666666666667	ORC5 ORC2 ORC3 ORC6	Activation of ATR in response to replication stress
WP:WP45	1.79003354063e-07	0.666666666667	ORC5 ORC2 ORC3 ORC6	G1 to S cell cycle control
REAC:R-HSA-68827	5.42829555401e-07	0.666666666667	ORC5 ORC2 ORC3 ORC6	CDT1 association with the CDC6:ORC:origin complex
REAC:R-HSA-68867	9.70376566633e-07	0.666666666667	ORC5 ORC2 ORC3 ORC6	Assembly of the pre-replicative complex
REAC:R-HSA-68949	1.15737262627e-06	0.666666666667	ORC5 ORC2 ORC3 ORC6	Orc1 removal from chromatin
WP:WP179	2.13945232833e-06	0.666666666667	ORC5 ORC2 ORC3 ORC6	Cell Cycle
REAC:R-HSA-69002	2.40820312913e-06	0.666666666667	ORC5 ORC2 ORC3 ORC6	DNA Replication Pre-Initiation
KEGG:04110	2.74873837611e-06	0.666666666667	ORC5 ORC2 ORC3 ORC6	Cell cycle
REAC:R-HSA-69052	2.90272483296e-06	0.666666666667	ORC5 ORC2 ORC3 ORC6	Switching of origins to a post-replicative state
GO:0003688	3.88005641427e-06	0.666666666667	ORC5 ORC2 ORC3 ORC6	DNA replication origin binding
REAC:R-HSA-69239	9.09450019206e-06	0.666666666667	ORC5 ORC2 ORC3 ORC6	Synthesis of DNA
REAC:R-HSA-69306	1.18518696073e-05	0.666666666667	ORC5 ORC2 ORC3 ORC6	DNA Replication
GO:0006261	1.24105644798e-05	0.833333333333	ORC2 ORC5 ORC3 LRWD1 ORC6	DNA-dependent DNA replication
REAC:R-HSA-69206	1.3444306072e-05	0.666666666667	ORC5 ORC2 ORC3 ORC6	G1/S Transition
REAC:R-HSA-453279	2.20593865609e-05	0.666666666667	ORC5 ORC2 ORC3 ORC6	Mitotic G1-G1/S phases
CORUM:1032	2.51655344529e-05	0.333333333333	ORC3 ORC2	ORC 2-4 complex (origin recognition 2-4 complex)
REAC:R-HSA-69242	3.02487101892e-05	0.666666666667	ORC5 ORC2 ORC3 ORC6	S Phase
REAC:R-HSA-69481	3.68471857477e-05	0.666666666667	ORC5 ORC2 ORC3 ORC6	G2/M Checkpoints
GO:0006260	0.000150202934951	0.833333333333	ORC2 ORC5 ORC3 LRWD1 ORC6	DNA replication
REAC:R-HSA-69620	0.000322105305692	0.666666666667	ORC5 ORC2 ORC3 ORC6	Cell Cycle Checkpoints
REAC:R-HSA-69278	0.00331294271573	0.666666666667	ORC5 ORC2 ORC3 ORC6	Cell Cycle, Mitotic
GO:0000781	0.00537058982175	0.666666666667	ORC5 ORC2 LRWD1 ORC3	chromosome, telomeric region
REAC:R-HSA-1640170	0.00675311119139	0.666666666667	ORC5 ORC2 ORC3 ORC6	Cell Cycle
GO:0000082	0.0236425639653	0.666666666667	ORC5 ORC2 ORC3 ORC6	G1/S transition of mitotic cell cycle
GO:0044843	0.0298264479231	0.666666666667	ORC5 ORC2 ORC3 ORC6	cell cycle G1/S phase transition
CORUM:2205	0.0499726005494	0.166666666667	ORC5	ORC5-ORC1 complex

Protein 1	Protein 2	Score ?	Precision ?	Evidence ?
LRWD1	ORC2	1.0	0.949	hein_WMM     bioplex_WMM     youn_WMM     hein (LRWD1,ORC2)     Malo     gupta_WMM     fraction
ORC6	ORC2	0.702	0.723	bioplex (ORC6)     bioplex_WMM
LRWD1	ORC5	0.157	0.416	hein_WMM     bioplex_WMM     youn_WMM     hein (LRWD1)     gupta_WMM
ORC3	ORC2	0.109	0.378	bioplex_WMM     youn_WMM     Malo     gupta_WMM     fraction
ORC5	ORC2	0.066	0.35	hein_WMM     bioplex_WMM     youn_WMM     hein (ORC2)     gupta_WMM
RPGR	ORC3	0.054	0.302	bioplex (RPGR)     bioplex_WMM
RPGR	ORC2	0.043	0.268	bioplex (RPGR)     bioplex_WMM     gupta (RPGR)     gupta_WMM
LRWD1	ORC6	0.02	0.188	bioplex (ORC6)     bioplex_WMM
ORC6	ORC3	0.009	0.107	Guru     fraction
LRWD1	ORC3	0.008	0.078	bioplex_WMM     youn_WMM     gupta_WMM     WMM_only
RPGR	LRWD1	0.006	0.002	bioplex (RPGR)     bioplex_WMM
ORC5	ORC3	0.0	0.0	youn_WMM     gupta_WMM     fraction     treiber_WMM

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Complex HuMAP2_00864 has an average edge precision of 0.313 which is ranked 4425 out of all 6965 complexes.

Genename	Complexes
LRWD1	HuMAP2_00864 HuMAP2_02551 HuMAP2_04398 HuMAP2_04533
RPGR	HuMAP2_00333 HuMAP2_00699 HuMAP2_00864 HuMAP2_01782 HuMAP2_04078 HuMAP2_05152
ORC3	HuMAP2_00864 HuMAP2_01115 HuMAP2_02994 HuMAP2_04533 HuMAP2_04597
ORC5	HuMAP2_00864 HuMAP2_04533
ORC6	HuMAP2_00864 HuMAP2_02994 HuMAP2_04398 HuMAP2_04533
ORC2	HuMAP2_00864 HuMAP2_02994 HuMAP2_04398 HuMAP2_04533 HuMAP2_04597