hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00867
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| CHMP2A | Charged multivesicular body protein 2a (Chromatin-modifying protein 2a) (CHMP2a) (Putative breast adenocarcinoma marker BC-2) (Vacuolar protein sorting-associated protein 2-1) (Vps2-1) (hVps2-1) | UniProt NCBI |
| CHMP2B | Charged multivesicular body protein 2b (CHMP2.5) (Chromatin-modifying protein 2b) (CHMP2b) (Vacuolar protein sorting-associated protein 2-2) (Vps2-2) (hVps2-2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:1186 | 7.54165558069e-05 | 1.0 | CHMP2A CHMP2B | ESCRT-III complex |
| REAC:R-HSA-9615710 | 0.000588249135293 | 1.0 | CHMP2A CHMP2B | Microautophagy |
| REAC:R-HSA-162588 | 0.000633499068778 | 1.0 | CHMP2A CHMP2B | Budding and maturation of HIV virion |
| REAC:R-HSA-917729 | 0.000779304410004 | 1.0 | CHMP2A CHMP2B | Endosomal Sorting Complex Required For Transport (ESCRT) |
| KEGG:04217 | 0.0016743202165 | 1.0 | CHMP2A CHMP2B | Necroptosis |
| KEGG:04144 | 0.00387576825996 | 1.0 | CHMP2A CHMP2B | Endocytosis |
| REAC:R-HSA-1632852 | 0.00626962967274 | 1.0 | CHMP2A CHMP2B | Macroautophagy |
| REAC:R-HSA-9612973 | 0.00880362594785 | 1.0 | CHMP2A CHMP2B | Autophagy |
| REAC:R-HSA-162599 | 0.0147112561527 | 1.0 | CHMP2A CHMP2B | Late Phase of HIV Life Cycle |
| REAC:R-HSA-162587 | 0.0177396498492 | 1.0 | CHMP2A CHMP2B | HIV Life Cycle |
| GO:0000815 | 0.020287053512 | 1.0 | CHMP2A CHMP2B | ESCRT III complex |
| GO:1904896 | 0.020287053512 | 1.0 | CHMP2A CHMP2B | ESCRT complex disassembly |
| GO:1904903 | 0.020287053512 | 1.0 | CHMP2A CHMP2B | ESCRT III complex disassembly |
| GO:0045324 | 0.0351642260875 | 1.0 | CHMP2A CHMP2B | late endosome to vacuole transport |
| GO:1902188 | 0.0351642260875 | 1.0 | CHMP2A CHMP2B | positive regulation of viral release from host cell |
| REAC:R-HSA-162906 | 0.0414841334642 | 1.0 | CHMP2A CHMP2B | HIV Infection |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| CHMP2B | CHMP2A | 0.462 | 0.6 | hein_WMM Guru fraction |
Images
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Complex HuMAP2_00867 has an average edge precision of 0.6 which is ranked 1947 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| CHMP2A | HuMAP2_00578 HuMAP2_00867 HuMAP2_01274 HuMAP2_06208 HuMAP2_06457 HuMAP2_06627 |
| CHMP2B | HuMAP2_00578 HuMAP2_00867 HuMAP2_01274 HuMAP2_05586 HuMAP2_06208 HuMAP2_06386 HuMAP2_06914 |