hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00869
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| AKR1E2 | 1,5-anhydro-D-fructose reductase (AF reductase) (EC 1.1.1.263) (Aldo-keto reductase family 1 member C-like protein 2) (Aldo-keto reductase family 1 member E2) (LoopADR) (Testis aldo-keto reductase) (htAKR) (Testis-specific protein) (hTSP) | UniProt NCBI |
| PCBD2 | Pterin-4-alpha-carbinolamine dehydratase 2 (PHS 2) (EC 4.2.1.96) (4-alpha-hydroxy-tetrahydropterin dehydratase 2) (DcoH-like protein DCoHm) (Dimerization cofactor of hepatocyte nuclear factor 1 from muscle) (HNF-1-alpha dimerization cofactor) | UniProt NCBI |
| QDPR | Dihydropteridine reductase (EC 1.5.1.34) (HDHPR) (Quinoid dihydropteridine reductase) (Short chain dehydrogenase/reductase family 33C member 1) | UniProt NCBI |
| GDA | Guanine deaminase (Guanase) (Guanine aminase) (EC 3.5.4.3) (Guanine aminohydrolase) (GAH) (p51-nedasin) | UniProt NCBI |
| ADSL | Adenylosuccinate lyase (ADSL) (ASL) (EC 4.3.2.2) (Adenylosuccinase) (ASase) | UniProt NCBI |
| BLMH | Bleomycin hydrolase (BH) (BLM hydrolase) (BMH) (EC 3.4.22.40) | UniProt NCBI |
| UROD | Uroporphyrinogen decarboxylase (UPD) (URO-D) (EC 4.1.1.37) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:00790 | 0.00320794449845 | 0.285714285714 | PCBD2 QDPR | Folate biosynthesis |
| KEGG:01100 | 0.00448611596597 | 0.714285714286 | ADSL QDPR UROD GDA PCBD2 | Metabolic pathways |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| UROD | BLMH | 0.994 | 0.923 | fraction |
| BLMH | QDPR | 0.778 | 0.752 | bioplex (BLMH) bioplex_WMM fraction |
| UROD | QDPR | 0.644 | 0.687 | fraction |
| BLMH | ADSL | 0.307 | 0.502 | fraction treiber_WMM |
| GDA | QDPR | 0.238 | 0.47 | fraction |
| ADSL | QDPR | 0.102 | 0.365 | fraction |
| ADSL | PCBD2 | 0.077 | 0.352 | fraction |
| UROD | ADSL | 0.067 | 0.35 | youn_WMM fraction |
| GDA | ADSL | 0.067 | 0.351 | fraction |
| AKR1E2 | ADSL | 0.048 | 0.294 | fraction |
| PCBD2 | QDPR | 0.003 | 0.012 | fraction |
| BLMH | GDA | 0.003 | 0.011 | fraction |
| UROD | GDA | 0.0 | 0.001 | fraction |
Images
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Complex HuMAP2_00869 has an average edge precision of 0.39 which is ranked 3424 out of all 6965 complexes.
Related Complexes