hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00894
Confidence: Medium
Proteins| Genename | Protein Name | Links |
|---|---|---|
| FAM162A | Protein FAM162A (E2-induced gene 5 protein) (Growth and transformation-dependent protein) (HGTD-P) | UniProt NCBI |
| MCU | Calcium uniporter protein, mitochondrial (HsMCU) (Coiled-coil domain-containing protein 109A) | UniProt NCBI |
| FBLN7 | Fibulin-7 (FIBL-7) | UniProt NCBI |
| STEAP3 | Metalloreductase STEAP3 (EC 1.16.1.-) (Dudulin-2) (Six-transmembrane epithelial antigen of prostate 3) (Tumor suppressor-activated pathway protein 6) (hTSAP6) (pHyde) (hpHyde) | UniProt NCBI |
| MCUB | Calcium uniporter regulatory subunit MCUb, mitochondrial (MCUb) (Coiled-coil domain-containing protein 109B) | UniProt NCBI |
| ASPH | Aspartyl/asparaginyl beta-hydroxylase (EC 1.14.11.16) (Aspartate beta-hydroxylase) (ASP beta-hydroxylase) (Peptide-aspartate beta-dioxygenase) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| CORUM:6473 | 8.38550741504e-05 | 0.333333333333 | MCUB MCU | mitochondrial calcium uniporter complex |
| REAC:R-HSA-8949664 | 0.00265393377546 | 0.333333333333 | MCUB MCU | Processing of SMDT1 |
| REAC:R-HSA-8949215 | 0.0055883638448 | 0.333333333333 | MCUB MCU | Mitochondrial calcium ion transport |
| REAC:R-HSA-382551 | 0.00608967581104 | 0.666666666667 | MCUB MCU STEAP3 ASPH | Transport of small molecules |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| ASPH | MCU | 0.198 | 0.45 | bioplex (ASPH) bioplex_WMM |
| MCUB | ASPH | 0.146 | 0.409 | bioplex (ASPH) bioplex_WMM |
| FBLN7 | ASPH | 0.059 | 0.331 | bioplex (FBLN7) bioplex_WMM |
| ASPH | FAM162A | 0.045 | 0.286 | bioplex (ASPH) bioplex_WMM boldt boldt_WMM |
| STEAP3 | ASPH | 0.038 | 0.264 | bioplex (ASPH) bioplex_WMM boldt (STEAP3) gupta_WMM boldt_WMM |
| MCUB | MCU | 0.008 | 0.087 | bioplex_WMM WMM_only boldt_WMM |
| MCUB | STEAP3 | 0.007 | 0.002 | bioplex_WMM WMM_only |
| STEAP3 | MCU | 0.007 | 0.007 | bioplex_WMM youn_WMM WMM_only |
| MCUB | FAM162A | 0.007 | 0.009 | bioplex_WMM WMM_only |
| STEAP3 | FAM162A | 0.006 | 0.009 | bioplex_WMM WMM_only |
| FAM162A | MCU | 0.006 | 0.004 | bioplex_WMM WMM_only |
Images
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Complex HuMAP2_00894 has an average edge precision of 0.169 which is ranked 6542 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| FAM162A | HuMAP2_00894 HuMAP2_04380 |
| MCU | HuMAP2_00894 HuMAP2_04380 |
| FBLN7 | HuMAP2_00894 HuMAP2_04380 |
| STEAP3 | HuMAP2_00894 HuMAP2_01569 HuMAP2_06778 |
| MCUB | HuMAP2_00567 HuMAP2_00894 HuMAP2_01263 HuMAP2_01516 HuMAP2_02716 HuMAP2_04380 |
| ASPH | HuMAP2_00894 HuMAP2_04380 |