hu.MAP 2.0: Complex View

Human Protein Complex Map

Genename	Protein Name	Links
CLDND1	Claudin domain-containing protein 1 (Membrane protein GENX-3745)	UniProt NCBI
MT-CYB	Cytochrome b (Complex III subunit 3) (Complex III subunit III) (Cytochrome b-c1 complex subunit 3) (Ubiquinol-cytochrome-c reductase complex cytochrome b subunit)	UniProt NCBI
ZDHHC8	Probable palmitoyltransferase ZDHHC8 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 8) (DHHC-8) (Zinc finger protein 378)	UniProt NCBI
GOLGA7	Golgin subfamily A member 7 (Golgi complex-associated protein of 16 kDa)	UniProt NCBI
ZDHHC5	Palmitoyltransferase ZDHHC5 (EC 2.3.1.225) (Zinc finger DHHC domain-containing protein 5) (DHHC-5) (Zinc finger protein 375)	UniProt NCBI
GOLGA7B	Golgin subfamily A member 7B	UniProt NCBI
MAN1A2	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IB (EC 3.2.1.113) (Mannosidase alpha class 1A member 2) (Processing alpha-1,2-mannosidase IB) (Alpha-1,2-mannosidase IB)	UniProt NCBI
MAN1A1	Mannosyl-oligosaccharide 1,2-alpha-mannosidase IA (EC 3.2.1.113) (Man(9)-alpha-mannosidase) (Man9-mannosidase) (Mannosidase alpha class 1A member 1) (Processing alpha-1,2-mannosidase IA) (Alpha-1,2-mannosidase IA)	UniProt NCBI
KIAA2013	Uncharacterized protein KIAA2013	UniProt NCBI

Term ID	Corrected Pval	Fraction Complex Coverage	Proteins	Term Name
GO:0018345	5.3613412156e-05	0.444444444444	GOLGA7 ZDHHC5 GOLGA7B ZDHHC8	protein palmitoylation
GO:0016409	0.00012480473255	0.444444444444	GOLGA7 ZDHHC5 GOLGA7B ZDHHC8	palmitoyltransferase activity
REAC:R-HSA-964827	0.000193919007602	0.222222222222	MAN1A1 MAN1A2	Progressive trimming of alpha-1,2-linked mannose residues from Man9/8/7GlcNAc2 to produce Man5GlcNAc2
REAC:R-HSA-964739	0.000645991629451	0.222222222222	MAN1A1 MAN1A2	N-glycan trimming and elongation in the cis-Golgi
GO:0006497	0.00310500088273	0.444444444444	GOLGA7 ZDHHC5 GOLGA7B ZDHHC8	protein lipidation
GO:0042158	0.00328411577048	0.444444444444	GOLGA7 ZDHHC5 GOLGA7B ZDHHC8	lipoprotein biosynthetic process
GO:0042157	0.00580463861904	0.444444444444	GOLGA7 ZDHHC5 GOLGA7B ZDHHC8	lipoprotein metabolic process
GO:0019706	0.010091186376	0.333333333333	GOLGA7 ZDHHC8 GOLGA7B	protein-cysteine S-palmitoyltransferase activity
GO:0019707	0.010091186376	0.333333333333	GOLGA7 ZDHHC8 GOLGA7B	protein-cysteine S-acyltransferase activity
KEGG:00513	0.0103544297971	0.222222222222	MAN1A1 MAN1A2	Various types of N-glycan biosynthesis
GO:0016417	0.0153428859848	0.333333333333	GOLGA7 ZDHHC8 GOLGA7B	S-acyltransferase activity
KEGG:00510	0.0155091288123	0.222222222222	MAN1A1 MAN1A2	N-Glycan biosynthesis
GO:1904381	0.0486736709081	0.222222222222	MAN1A1 MAN1A2	Golgi apparatus mannose trimming

Protein 1	Protein 2	Score	Precision	Evidence
ZDHHC5	CLDND1	0.997	0.93	bioplex (CLDND1) bioplex_WMM gupta_WMM
CLDND1	ZDHHC8	0.995	0.924	bioplex (CLDND1) bioplex_WMM gupta_WMM
CLDND1	GOLGA7	0.973	0.886	bioplex (CLDND1) bioplex_WMM
CLDND1	MAN1A1	0.74	0.738	bioplex (CLDND1) bioplex_WMM
ZDHHC5	GOLGA7B	0.528	0.634	bioplex (GOLGA7B) bioplex_WMM
CLDND1	MAN1A2	0.124	0.396	bioplex (CLDND1) bioplex_WMM
CLDND1	MT-CYB	0.042	0.27	bioplex (CLDND1) bioplex_WMM
CLDND1	KIAA2013	0.024	0.214	bioplex (CLDND1) bioplex_WMM
ZDHHC5	GOLGA7	0.01	0.14	bioplex_WMM WMM_only
MAN1A1	MAN1A2	0.01	0.116	bioplex_WMM WMM_only
ZDHHC5	ZDHHC8	0.009	0.103	bioplex_WMM gupta_WMM WMM_only
MT-CYB	ZDHHC8	0.009	0.089	bioplex_WMM WMM_only
ZDHHC8	GOLGA7	0.008	0.094	bioplex_WMM WMM_only
MAN1A1	ZDHHC8	0.008	0.089	bioplex_WMM WMM_only
MAN1A2	ZDHHC8	0.008	0.06	bioplex_WMM WMM_only
ZDHHC5	MT-CYB	0.008	0.052	bioplex_WMM WMM_only
MT-CYB	GOLGA7	0.008	0.032	bioplex_WMM WMM_only
MAN1A1	MT-CYB	0.008	0.026	bioplex_WMM WMM_only
ZDHHC5	MAN1A1	0.008	0.015	bioplex_WMM WMM_only
ZDHHC8	KIAA2013	0.007	0.009	bioplex_WMM WMM_only
MAN1A1	GOLGA7	0.007	0.006	bioplex_WMM WMM_only
MAN1A2	MT-CYB	0.007	0.005	bioplex_WMM WMM_only
ZDHHC5	MAN1A2	0.007	0.0	bioplex_WMM WMM_only
MAN1A2	GOLGA7	0.007	0.001	bioplex_WMM WMM_only
MT-CYB	KIAA2013	0.007	0.004	bioplex_WMM WMM_only
ZDHHC5	KIAA2013	0.007	0.006	bioplex_WMM WMM_only
GOLGA7	KIAA2013	0.007	0.005	bioplex_WMM WMM_only
MAN1A1	KIAA2013	0.007	0.0	bioplex_WMM WMM_only
MAN1A2	KIAA2013	0.006	0.008	bioplex_WMM WMM_only

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Complex HuMAP2_00899 has an average edge precision of 0.202 which is ranked 6156 out of all 6965 complexes.