hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00907
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| ESYT1 | Extended synaptotagmin-1 (E-Syt1) (Membrane-bound C2 domain-containing protein) | UniProt NCBI |
| TEX264 | Testis-expressed protein 264 (Putative secreted protein Zsig11) | UniProt NCBI |
| PREB | Prolactin regulatory element-binding protein (Mammalian guanine nucleotide exchange factor mSec12) | UniProt NCBI |
| CDKAL1 | Threonylcarbamoyladenosine tRNA methylthiotransferase (EC 2.8.4.5) (CDK5 regulatory subunit-associated protein 1-like 1) (tRNA-t(6)A37 methylthiotransferase) | UniProt NCBI |
| VRK2 | Serine/threonine-protein kinase VRK2 (EC 2.7.11.1) (Vaccinia-related kinase 2) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:0005789 | 0.00914809389328 | 1.0 | PREB ESYT1 VRK2 CDKAL1 TEX264 | endoplasmic reticulum membrane |
| GO:0042175 | 0.00992532516881 | 1.0 | PREB ESYT1 VRK2 CDKAL1 TEX264 | nuclear outer membrane-endoplasmic reticulum membrane network |
| GO:0044432 | 0.0440230022293 | 1.0 | PREB ESYT1 VRK2 CDKAL1 TEX264 | endoplasmic reticulum part |
| CORUM:7313 | 0.0499494897235 | 0.2 | ESYT1 | ESYT1-ESYT2 complex |
| CORUM:7314 | 0.0499494897235 | 0.2 | ESYT1 | ESYT1-ESYT3 complex |
| CORUM:7477 | 0.0499494897235 | 0.2 | PREB | TANGO1L-cTAGE5-SEC12 complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| TEX264 | PREB | 0.555 | 0.647 | bioplex (TEX264) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| TEX264 | ESYT1 | 0.148 | 0.409 | bioplex (TEX264) bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| TEX264 | VRK2 | 0.076 | 0.355 | bioplex (TEX264) bioplex_WMM youn_WMM gupta_WMM |
| TEX264 | CDKAL1 | 0.054 | 0.302 | bioplex (TEX264) bioplex_WMM youn_WMM gupta_WMM |
| PREB | CDKAL1 | 0.011 | 0.14 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM |
| CDKAL1 | VRK2 | 0.009 | 0.109 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| PREB | VRK2 | 0.008 | 0.085 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| ESYT1 | CDKAL1 | 0.008 | 0.013 | bioplex (CDKAL1) bioplex_WMM youn_WMM gupta_WMM |
| ESYT1 | VRK2 | 0.004 | 0.011 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
| ESYT1 | PREB | 0.003 | 0.018 | bioplex_WMM youn_WMM gupta_WMM WMM_only |
Images
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Complex HuMAP2_00907 has an average edge precision of 0.209 which is ranked 6043 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| ESYT1 | HuMAP2_00287 HuMAP2_00907 HuMAP2_01322 HuMAP2_06362 |
| TEX264 | HuMAP2_00287 HuMAP2_00907 HuMAP2_04372 HuMAP2_06362 |
| PREB | HuMAP2_00287 HuMAP2_00907 HuMAP2_03233 HuMAP2_04372 HuMAP2_06362 |
| CDKAL1 | HuMAP2_00907 HuMAP2_05732 HuMAP2_06362 |
| VRK2 | HuMAP2_00907 HuMAP2_01801 |