hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00927
Confidence: High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| SYNCRIP | Heterogeneous nuclear ribonucleoprotein Q (hnRNP Q) (Glycine- and tyrosine-rich RNA-binding protein) (GRY-RBP) (NS1-associated protein 1) (Synaptotagmin-binding, cytoplasmic RNA-interacting protein) | UniProt NCBI |
| UPF1 | Regulator of nonsense transcripts 1 (EC 3.6.4.-) (ATP-dependent helicase RENT1) (Nonsense mRNA reducing factor 1) (NORF1) (Up-frameshift suppressor 1 homolog) (hUpf1) | UniProt NCBI |
| KHDRBS1 | KH domain-containing, RNA-binding, signal transduction-associated protein 1 (GAP-associated tyrosine phosphoprotein p62) (Src-associated in mitosis 68 kDa protein) (Sam68) (p21 Ras GTPase-activating protein-associated p62) (p68) | UniProt NCBI |
| HNRNPA1 | Heterogeneous nuclear ribonucleoprotein A1 (hnRNP A1) (Helix-destabilizing protein) (Single-strand RNA-binding protein) (hnRNP core protein A1) [Cleaved into: Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed] | UniProt NCBI |
| MOV10 | Helicase MOV-10 (EC 3.6.4.13) (Armitage homolog) (Moloney leukemia virus 10 protein) | UniProt NCBI |
| THUMPD1 | THUMP domain-containing protein 1 | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| GO:1903311 | 0.000744794151254 | 0.833333333333 | HNRNPA1 MOV10 UPF1 KHDRBS1 SYNCRIP | regulation of mRNA metabolic process |
| CORUM:1181 | 0.0248542652474 | 0.333333333333 | HNRNPA1 SYNCRIP | C complex spliceosome |
| GO:0003723 | 0.0386338629612 | 1.0 | HNRNPA1 SYNCRIP THUMPD1 MOV10 UPF1 KHDRBS1 | RNA binding |
| CORUM:644 | 0.0499726005494 | 0.166666666667 | KHDRBS1 | ASPP1-SAM68 complex |
| CORUM:2578 | 0.0499726005494 | 0.166666666667 | KHDRBS1 | Sam68-p120GAP complex |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| KHDRBS1 | SYNCRIP | 0.985 | 0.899 | hein_WMM youn (SYNCRIP) bioplex (SYNCRIP) bioplex_WMM Guru youn_WMM gupta_WMM fraction boldt_WMM treiber_WMM |
| THUMPD1 | SYNCRIP | 0.891 | 0.818 | bioplex (THUMPD1) youn_WMM gupta_WMM fraction treiber_WMM |
| MOV10 | SYNCRIP | 0.863 | 0.8 | hein_WMM youn (MOV10,SYNCRIP) bioplex (SYNCRIP) bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| UPF1 | SYNCRIP | 0.785 | 0.757 | youn (SYNCRIP) bioplex (SYNCRIP) bioplex_WMM Guru youn_WMM gupta_WMM fraction treiber_WMM |
| KHDRBS1 | HNRNPA1 | 0.696 | 0.718 | hein_WMM bioplex (HNRNPA1) bioplex_WMM boldt hein (HNRNPA1) gupta_WMM fraction boldt_WMM treiber_WMM |
| UPF1 | MOV10 | 0.61 | 0.674 | youn (MOV10) bioplex_WMM youn_WMM gupta_WMM fraction treiber_WMM |
| SYNCRIP | HNRNPA1 | 0.549 | 0.643 | hein_WMM youn (SYNCRIP) bioplex (HNRNPA1,SYNCRIP) bioplex_WMM boldt hein (HNRNPA1) gupta_WMM fraction boldt_WMM treiber_WMM |
| UPF1 | THUMPD1 | 0.027 | 0.228 | youn_WMM gupta_WMM fraction |
| UPF1 | KHDRBS1 | 0.007 | 0.003 | bioplex_WMM boldt youn_WMM gupta_WMM boldt_WMM treiber_WMM |
| MOV10 | KHDRBS1 | 0.007 | 0.006 | youn (MOV10) bioplex_WMM youn_WMM gupta_WMM |
| MOV10 | THUMPD1 | 0.007 | 0.001 | youn_WMM WMM_only |
| THUMPD1 | KHDRBS1 | 0.007 | 0.002 | youn_WMM gupta_WMM WMM_only |
| THUMPD1 | HNRNPA1 | 0.007 | 0.005 | bioplex (THUMPD1) gupta_WMM treiber_WMM |
| MOV10 | HNRNPA1 | 0.0 | 0.008 | youn (MOV10) bioplex (HNRNPA1) bioplex_WMM gupta_WMM treiber_WMM |
| UPF1 | HNRNPA1 | 0.0 | 0.001 | bioplex (HNRNPA1) bioplex_WMM gupta_WMM treiber_WMM |
Images
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Complex HuMAP2_00927 has an average edge precision of 0.371 which is ranked 3633 out of all 6965 complexes.
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