hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00945
Confidence: Very High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| RPS17 | 40S ribosomal protein S17 (Small ribosomal subunit protein eS17) | UniProt NCBI |
| RPL35 | 60S ribosomal protein L35 (Large ribosomal subunit protein uL29) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| KEGG:03010 | 0.00122335090758 | 1.0 | RPL35 RPS17 | Ribosome |
| WP:WP477 | 0.00139382676196 | 1.0 | RPL35 RPS17 | Cytoplasmic Ribosomal Proteins |
| HP:0001972 | 0.00360992672371 | 1.0 | RPL35 RPS17 | Macrocytic anemia |
| CORUM:306 | 0.00516352018758 | 1.0 | RPL35 RPS17 | Ribosome, cytoplasmic |
| REAC:R-HSA-192823 | 0.00641543501397 | 1.0 | RPL35 RPS17 | Viral mRNA Translation |
| REAC:R-HSA-156902 | 0.00641543501397 | 1.0 | RPL35 RPS17 | Peptide chain elongation |
| REAC:R-HSA-156842 | 0.0070154156135 | 1.0 | RPL35 RPS17 | Eukaryotic Translation Elongation |
| REAC:R-HSA-72764 | 0.0070154156135 | 1.0 | RPL35 RPS17 | Eukaryotic Translation Termination |
| REAC:R-HSA-2408557 | 0.0070154156135 | 1.0 | RPL35 RPS17 | Selenocysteine synthesis |
| REAC:R-HSA-975956 | 0.00732546145404 | 1.0 | RPL35 RPS17 | Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC) |
| REAC:R-HSA-72689 | 0.00829582113875 | 1.0 | RPL35 RPS17 | Formation of a pool of free 40S subunits |
| CORUM:3055 | 0.00863268175469 | 1.0 | RPL35 RPS17 | Nop56p-associated pre-rRNA complex |
| REAC:R-HSA-156827 | 0.0100471611569 | 1.0 | RPL35 RPS17 | L13a-mediated translational silencing of Ceruloplasmin expression |
| REAC:R-HSA-1799339 | 0.0102315127378 | 1.0 | RPL35 RPS17 | SRP-dependent cotranslational protein targeting to membrane |
| REAC:R-HSA-72706 | 0.0102315127378 | 1.0 | RPL35 RPS17 | GTP hydrolysis and joining of the 60S ribosomal subunit |
| REAC:R-HSA-927802 | 0.0106052436699 | 1.0 | RPL35 RPS17 | Nonsense-Mediated Decay (NMD) |
| REAC:R-HSA-975957 | 0.0106052436699 | 1.0 | RPL35 RPS17 | Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) |
| REAC:R-HSA-2408522 | 0.0107946230212 | 1.0 | RPL35 RPS17 | Selenoamino acid metabolism |
| HP:0002488 | 0.0110902559199 | 1.0 | RPL35 RPS17 | Acute leukemia |
| REAC:R-HSA-72737 | 0.0115688996608 | 1.0 | RPL35 RPS17 | Cap-dependent Translation Initiation |
| REAC:R-HSA-72613 | 0.0115688996608 | 1.0 | RPL35 RPS17 | Eukaryotic Translation Initiation |
| REAC:R-HSA-168273 | 0.014052618232 | 1.0 | RPL35 RPS17 | Influenza Viral RNA Transcription and Replication |
| REAC:R-HSA-168255 | 0.0158425044898 | 1.0 | RPL35 RPS17 | Influenza Life Cycle |
| HP:0000457 | 0.0175420398516 | 1.0 | RPL35 RPS17 | Depressed nasal ridge |
| REAC:R-HSA-168254 | 0.0182306954237 | 1.0 | RPL35 RPS17 | Influenza Infection |
| HP:0002076 | 0.0226613901453 | 1.0 | RPL35 RPS17 | Migraine |
| HP:0000980 | 0.0230521037685 | 1.0 | RPL35 RPS17 | Pallor |
| REAC:R-HSA-9010553 | 0.0235098543302 | 1.0 | RPL35 RPS17 | Regulation of expression of SLITs and ROBOs |
| HP:0001909 | 0.0242442812341 | 1.0 | RPL35 RPS17 | Leukemia |
| HP:0010972 | 0.0250557633746 | 1.0 | RPL35 RPS17 | Anemia of inadequate production |
| REAC:R-HSA-6791226 | 0.0273007932021 | 1.0 | RPL35 RPS17 | Major pathway of rRNA processing in the nucleolus and cytosol |
| HP:0000179 | 0.0302051685624 | 1.0 | RPL35 RPS17 | Thick lower lip vermilion |
| REAC:R-HSA-8868773 | 0.0304096312248 | 1.0 | RPL35 RPS17 | rRNA processing in the nucleus and cytosol |
| REAC:R-HSA-72312 | 0.0336860615937 | 1.0 | RPL35 RPS17 | rRNA processing |
| REAC:R-HSA-376176 | 0.0378389999335 | 1.0 | RPL35 RPS17 | Signaling by ROBO receptors |
| HP:0000823 | 0.0408946925611 | 1.0 | RPL35 RPS17 | Delayed puberty |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| RPS17 | RPL35 | 0.84 | 0.784 | hein_WMM bioplex_WMM boldt youn_WMM hein (RPL35) gupta_WMM boldt_WMM treiber_WMM |
Images
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Complex HuMAP2_00945 has an average edge precision of 0.784 which is ranked 986 out of all 6965 complexes.
Related Complexes
| Genename | Complexes |
|---|---|
| RPS17 | HuMAP2_00215 HuMAP2_00608 HuMAP2_00945 |
| RPL35 | HuMAP2_00608 HuMAP2_00945 HuMAP2_02207 HuMAP2_05622 HuMAP2_06948 |