hu.MAP 2.0: Complex View
Human Protein Complex Map
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Complex: HuMAP2_00950
Confidence: Medium High
Proteins| Genename | Protein Name | Links |
|---|---|---|
| OTUD6B | Deubiquitinase OTUD6B (EC 3.4.19.12) (DUBA-5) (OTU domain-containing protein 6B) | UniProt NCBI |
| HSPA14 | Heat shock 70 kDa protein 14 (HSP70-like protein 1) (Heat shock protein HSP60) | UniProt NCBI |
| DENR | Density-regulated protein (DRP) (Protein DRP1) (Smooth muscle cell-associated protein 3) (SMAP-3) | UniProt NCBI |
| DOCK11 | Dedicator of cytokinesis protein 11 (Activated Cdc42-associated guanine nucleotide exchange factor) (ACG) (Zizimin-2) | UniProt NCBI |
| NFAM1 | NFAT activation molecule 1 (Calcineurin/NFAT-activating ITAM-containing protein) (NFAT-activating protein with ITAM motif 1) | UniProt NCBI |
| MCTS1 | Malignant T-cell-amplified sequence 1 (MCT-1) (Multiple copies T-cell malignancies) | UniProt NCBI |
Enrichments
| Term ID | Corrected Pval | Fraction Complex Coverage | Proteins | Term Name |
|---|---|---|---|---|
| MIRNA:hsa-miR-6845-3p | 0.0179917044516 | 0.5 | NFAM1 DENR MCTS1 | hsa-miR-6845-3p |
| GO:0002188 | 0.020283420769 | 0.333333333333 | MCTS1 DENR | translation reinitiation |
Edges
| Protein 1 | Protein 2 | Score | Precision | Evidence |
|---|---|---|---|---|
| DENR | MCTS1 | 1.0 | 0.949 | bioplex (DENR) bioplex_WMM gupta_WMM fraction |
| MCTS1 | OTUD6B | 0.998 | 0.944 | fraction |
| DENR | DOCK11 | 0.198 | 0.45 | bioplex (DENR) bioplex_WMM |
| DENR | OTUD6B | 0.116 | 0.386 | fraction |
| HSPA14 | MCTS1 | 0.077 | 0.351 | bioplex_WMM fraction |
| HSPA14 | NFAM1 | 0.057 | 0.324 | bioplex (NFAM1) bioplex_WMM |
| HSPA14 | DENR | 0.009 | 0.108 | fraction |
| DOCK11 | MCTS1 | 0.008 | 0.09 | bioplex_WMM WMM_only |
| HSPA14 | OTUD6B | 0.004 | 0.014 | fraction |
Images
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Complex HuMAP2_00950 has an average edge precision of 0.402 which is ranked 3297 out of all 6965 complexes.
Related Complexes